Modern man lives in a frantic rhythm. Constant stressful situations, inability to have a good rest, poor ecology, poor diet, and the very quality of the food consumed - all these factors weaken the body over time. And there is no doubt that sooner or later, tired of overvoltage, he will somehow remind himself. The person, as they say, falls ill out of the blue - from a light blow of the breeze, changing weather, etc., due to the weakening of the immune system. To support and stimulate it, the drug Polyoxidonium was developed.
Operating principle
The secret of this modern drug is that it has a complex effect on the human body. The drug is both a powerful immunomodulator and an effective detoxifier, while being a good antioxidant medication. That is, "Polyoxidonium" will quickly remove the inflammatory process itself and the intoxication caused by it in the body, at the same time it will simulate the natural response of the immune system.
A distinctive feature of the drug "Polyoxidonium" (its analogues are far from always boasting such properties) is the ability to influence the immune system, depending on what condition it is in each particular patient. Simply put, indicators with values ââbelow the norm will be increased, and overvalued will be lowered. This property allows you to assign the drug to the patient, without conducting preliminary complex immunological studies.
In addition, "Polyoxidonium" as a sponge attracts various harmful substances to its surface and removes them from the body. Such substances include active oxygen radicals and lipid oxidation products, whose role in the push to the development of such formidable diseases as oncology, autoimmune processes, and atherosclerosis is quite significant.
The drug can help the body in the fight against infections of various etymologies. It can be local and generalized infectious lesions, fungal or bacterial diseases, viral pathologies. The mechanism of influence of "Polyoxidonium" is the activation of phagocytosis and antibody synthesis. The medication acts on phagocytes and NK cells, which increase the production of cytokines. The main function of this substance is the destruction of the pathogenic environment.
Release Forms
The medicine has a very wide field of use, and in order to be conveniently used, manufacturers offer consumers the following forms of the Polyoxidonium drug: tablets, lyophilisate and suppositories. From the lyophilisate produced in ampoules, injection solutions and drops are subsequently prepared. Depending on the observed pathology, the attending physician may recommend this or that form to achieve the most effective result.
Suppositories are offered to consumers in two dosage forms: 6 and 12 mg of the active ingredient (azoximer bromide). Lyophilisate is also available in two dosages - 6 and 12 mg of the main substance. Tablets are made only in a dose of 12 mg.
Quite often you can hear how consumers talk about the drug "Polyoxidonium" - "injections and drops." In fact, this medication in such forms is not available. Both that and another represents the solution prepared on the basis of lyophilisate. The composition thus prepared can subsequently be used both for intramuscular injection, and for intravenous administration through a dropper, and in the form of drops (it is permissible to drip under the tongue or instill into the nasal passages).
Area of ââuse "Polyodxidonium"
Tablets, suppositories, injections and drops have a different effect on each other when prescribing the Polyoxidonium immunostimulant. Drops under the tongue activate the work of local immunity. The result of this effect will be a high resistance of the body to infectious lesions from the respiratory system (nose, bronchi, Eustachian tubes). Pills will stimulate the activity of the immune cells of the digestive system. The result is an increase in the resistance of the respiratory system and gastrointestinal tract to various infections. In addition, tablets can effectively stimulate the functioning of immune cells in tissues. The result is an accelerated release of pathogenic microorganisms from the chronic foci of infections present in the body.
Possible therapeutic effects
The range of possible therapeutic effects of the Polyoxidonium medication (tablets, suppositories, injections and drops from the lyophilisate) is quite diverse. There may be a decrease in intoxication, a decrease in the intensity of the pain syndrome and the risk of complications in the form of bacterial infections. It has a persistent anti-inflammatory effect and accelerates the healing process. If there are any chronic pathologies in the body that have a viral, fungal or bacterial origin (chronic forms of tonsillitis, bronchitis, rhinitis, herpes, etc.), then under the influence of "Polyoxidonium" the remission period is significantly extended. The drug is able to smooth out the negative impact on the human body of medicines from groups of antibiotics, drugs used for fungal and viral diseases. "Polyoxidonium" will effectively help a person reduce the negative effects of taking bronchodilators, antihistamines, glucocorticoids.
Any immunomodulators - "Polyoxidonium", analogues of the drug - can significantly increase efficiency, improve overall health. It is acceptable to take Polyoxidonium together with antibiotics, antihistamines, antifungal drugs, cytostatics, bronchodilators. Modern immunomodulatory medication enhances the influence of the above medications, which allows to lower their dose for admission, reduce the treatment course, and increase the period of remission.
Tablets
The drug "Polyoxidonium" in this form of release can be swallowed or absorbed under the tongue. According to the instructions, you need to do this 30 minutes before eating, from one to three times a day. The dosage for adult patients is usually 12 or 24 mg. The severity of the disease and the severity of the condition affect the duration of the treatment course and the dosage regimen. For example, in the presence of inflammatory processes in the mouth and throat (stomatitis, pharyngitis), doctors usually prescribe 1 tablet twice a day. The treatment course can last up to 14 days. The same treatment period lasts in the presence of herpes or a fungal infection in the oral cavity, but tablets are taken three times a day. Twice a day, one tablet is taken by patients with otitis media and chronic sinusitis. Treatment lasts from 5 days to 10. In chronic forms of tonsillitis, tablets are prescribed three times a day for 10-15 days. For patients with chronic forms of upper respiratory tract diseases, the drug is prescribed as follows: twice a day, 2 tablets for 10-14 days.
Suppositories
Candles offered to customers are administered vaginally or rectally. The drug "Polyoxidonium" for children contains 6 mg of the active substance, for adults - 12 mg. With complex treatment, the drug can be used to correct immunity in a wide range of diseases. This may include chronic inflammatory processes of any etymology that are not amenable to standard therapy. The use of "Polyoxidonium" for infections of a viral or bacterial nature (colpitis, cystitis, prostatitis, pyelonephritis, urethritis, endometritis, etc.) will be justified. A good effect can be achieved by using the drug for various forms of tuberculosis, complex forms of allergies, rheumatoid arthritis. It is effective to use a medication to activate regeneration processes (trophic ulcers, fractures, burns), to conduct rehabilitation courses in often and for a long time sick people, and to take tumors during treatment (chemo- and radiation therapy).
As monotherapy, it is also possible to use candles. "Polyoxidonium" instruction recommends taking to prevent seasonal exacerbations of chronic infections, dormant in the body. Moreover, this is acceptable for elderly patients. Polyoxidonium monotherapy will be effective for the prevention of recurrence of herpes infections, for the correction of secondary forms of immunodeficiency caused by aging or the influence of adverse factors. A good result will be achieved when using suppositories of the drug as a prophylactic against influenza and acute respiratory infections.
The therapeutic dosage for adult patients leaves 12 mg, the prophylactic - 6 mg. Candles of the drug "Polyoxidonium" for children are prescribed by the attending doctor at the rate of 0.2-0.25 mg per 1 kilogram of weight.
Schematically, standard therapy is as follows: the first three days every day for 1 candle, the next 10-15 days - every other day for 1 candle. In general, treatment with Polyoxidonium is possible daily, every other day, or twice a week. It all depends on the disease and the severity of the patientâs state of health.
Depending on the dosage of suppositories of the Polyoxidonium preparation, the price per package may vary slightly.
Composition for injections and drops
The lyophilisate is used to make the drug composition for drops and injections of the Polyoxidonium preparation. Ampoules can be 3 and 6 mg in volume. For intramuscular injection , a 6 mg vial is combined with 1.5-2 ml of physiological saline (can be replaced with distilled water). In order to prepare a solution for intravenous administration, a 6 mg ampoule of lyophilisate is mixed with saline solution (2 ml), and a few more components are added: hemodes-H and reopoliglyukin. The latter can be replaced with a 5% dextrose solution. The composition obtained from all these substances is transferred to a dropper with a volume of 200-400 ml.
Children may be prescribed the medication "Polyoxidonium" in the nose or under the tongue in the form of drops. In addition, injections may be prescribed. The duration of the treatment period, the dosage and the manner in which the drug will be administered to the child are entirely dependent on the disease and can only be determined by the attending physician.
In order to prepare a solution for injections for a child, a lyophilisate in ampoules of 3 mg is used. It is impossible to store the prepared composition, it should be consumed immediately. When using the Polyoxidonium medication for injections, the dosage is prescribed at the rate of 100-150 ÎŒg per 1 kg of the child's weight (3 mg in one ampoule corresponds to 3000 ÎŒg). Children can be given Polyoxidonium injections starting at the age of 6 months.
Drops for instillation into the nose or under the tongue are also prepared on the basis of a lyophilisate. To a 6 mg vial, add 1 ml (20 drops) of saline (can be replaced with distilled water). It is allowed to store the prepared composition for instilling the Polyoxidonium drug in the refrigerator for 7 days. Application - with a frequency of 2-3 hours, 3 drops are instilled into each nasal passage. Depending on the severity of the disease, the treatment course can last from 1 day to 10 days.
Who should refrain from taking the drug?
All dosage forms of the Polyoxidonium medication (injections, suppositories, drops, tablets) should not be used by pregnant women and nursing mothers. This is due to the fact that there is currently no reliable information about the possible effects of the drug on the health of the expectant mother and the unborn child. The Polyoxidonium manual does not recommend taking any form of the drug (tablets, drops, injections, suppositories) for those who have increased sensitivity and especially individual intolerance to its components. Children under the age of six months are not prescribed suppositories and injections, and up to 12 years of age - tablets. If the patient suffers from acute liver failure, intolerance or lactose deficiency, Polyoxidonium is prescribed very carefully and under the strict supervision of the attending physician. Also, people suffering from malabsorption syndrome should be attentive to themselves .
Similar drugs
It has "Polyoxidonium" analogues in a fairly large amount. Of the most commonly used injections, immunostimulants such as âAktinolizatâ, âGelonâ, âGlutoximâ, âImunofanâ, âMoliksanâ solutions can be distinguished.
Drops of the Polyoxidonium preparation may have the following analogues: Vilosen, Poludan, Ruzam (can be administered subcutaneously), Floresil, Imunofan.
The list of analogs-suppositories is also quite extensive. The most commonly used candles include âGalavitâ, âImunofanâ, âMethylcracilâ (there is a form in tablets).
There are even more tablet counterparts in the modern medical market. Of the most popular, one can name âArpetolidâ, âArpefluâ, âGalavitâ, âEstifanâ, âNeuroferonâ.
A fairly large number of analogue immunostimulants are available in the form of sprays (Immunofan), suspensions (Imuron-vak, Uro-BCG), syrups (Bioaron S, Immunex), capsules (Broncho-Vaxom , Broncho-Munal, Isofon).
Price range
Since only one Russian pharmaceutical concern is engaged in the release of the Polyoxidonium medication, its price is quite high. A package of 10 tablets can be purchased for amounts from 650 rubles to 730. Suppositories with a dosage of 6 mg (10 pieces in one package) can cost from 720 rubles to 800. The same package of suppositories with a dose of 12 mg can be offered to customers for an amount of 830 up to 920 rubles. For the lyophilisate of the Polyoxidonium drug (3 mg ampoules, 5 vials per pack), the price ranges from 610 rubles to 740. The same package, but in a dosage of 6 mg, can cost the consumer from 910 rubles to 1030 .
To buy the drug in the pharmacy network, you must have a prescription. Buying "Polyoxidonium", you must pay attention to the date of manufacture and storage conditions. The medicine can be stored for two years from the date of manufacture. The best place for this is the refrigerator. If the drug is not stored properly, it may lose its healing properties and may not be enough or even not effective when used.
The drug "Polyoxidonium" has been on the pharmaceutical market for a rather long period. During this time, he gained a reputation as an effective and promising immunostimulant. The vast majority of patients who used the drug in the fight against a particular disease respond well to suppositories and suppositories "Polyoxidonium" just as a therapeutic drug, and not a preventive one. Medical specialists also speak positively about the Polyoxidonium drug. Ampoules (the price of lyophilisate is quite high) allows you to prepare a whole list of compositions for injection, droppers, drops in the nose and under the tongue. And use them to treat a large list of diseases.
However, no matter what positive characteristics the drug gives to neighbors or friends, one must remember that Polyoxidonium is an immunostimulant. Therefore, only the attending physician can decide on its purpose and select a dosage. Taking the drug without the advice of a doctor can be fraught with serious problems.