Rectal suppositories "Indomethacin" - a drug belonging to the NSAID group. The product has antipyretic activity, has an analgesic and anti-inflammatory effect. The drug has an inhibitory effect on cyclooxygenase, which leads to a violation in the synthesis of arachidonic acid and prostaglandins. The medicine helps suppress platelet aggregation. The medication relieves pain, especially pain and stiffness in the joints in the morning, at rest, and when moving. Against the background of local use, swelling decreases and erythema decreases. Anti-inflammatory effect develops at the end of the first week of use.
Indications
Suppositories "Indomethacin", the instructions for use recommends for pain in the spine, articular syndrome. In particular, the indications include gout, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis. The medication is prescribed for dysmenorrhea, traumatic inflammation in the joints and soft tissues, myalgia, neuralgia. As an auxiliary medicine, they are recommended for cystitis, prostatitis.
How to use Indomethacin Suppositories
Suppositories are injected deep into the rectum. Before the introduction, hygiene procedures should be carried out. Suppositories "Indomethacin", the instructions for use recommend use after treatment by intramuscular injection of the drug. Dosage 50-100 mg / day. It is recommended to use the drug at night. In severe pathologies, the dosage regimen is determined personally. The maximum dose per day is 200 mg.
Candles "Indomethacin". Instructions for use. Adverse reactions
Based on local use of the drug, allergic reactions to the mucous membranes and skin, itching in the anorectal region, and irritation are most often noted. Rarely, rectal lesions, gastrointestinal bleeding, exacerbation of chronic colitis are noted.
Candles "Indomethacin". Instructions for use. Contraindications
The drug is not recommended for erosive ulcerative lesions in the gastrointestinal tract, hypersensitivity. Contraindications include a disorder in the activity of the liver or kidneys, severe pancreatitis, pregnancy. Do not prescribe medication for recent bleeding from the rectum, in children under fourteen years old, with proctitis, cracks or other damage to the anus.
additional information
Caution is observed in the treatment of elderly patients, if the patient has renal or hepatic pathologies, a history of gastrointestinal system lesions, hypertension, dyspeptic manifestations during use. Dose adjustment may be required for epilepsy, cardiovascular disorders, immediately after surgery. In the presence of anamnestic data on intolerance to NSAIDs, the use of the drug is allowed only in emergency situations. The use of the drug simultaneously with acetylsalicylic acid is not recommended. Against the background of therapy, control over the state of the picture of peripheral blood, the activity of the liver and kidneys should be ensured.