Uterine endometriosis is a serious disease. It occurs in many women of childbearing age, it is dangerous for health, it can cause infertility and other pathologies. They treat this disease in different ways, but most often surgically. Is this ailment treated with medication? The fact is that at the moment, not a single cure for endometriosis can completely cure this disease. Despite this, medicines significantly slow down the development of pathology, relieve the symptoms of the disease.
What is endometriosis?
Endometriosis is a purely female disease that can occur in the uterus and ovaries. It is associated with excessive growth of the endometrium, covering the surface of the uterus. This is a special layer that helps the egg to catch during fertilization. Usually, after the egg is firmly fixed in the endometrium, the formation of vessels responsible for the development of the fetus occurs. If the pregnancy is terminated, the layer of the uterine mucosa exfoliates and exits along with the blood. The woman begins menstruation.
Endometriosis is of two types:
- Endometriosis is genital. With this pathology, the uterus and its neck, vagina, and ovaries are affected. This type of disease can be found in 85% of cases.
- Extra-genital endometriosis. With this type of disease, damage to the internal organs, bladder, intestines and postoperative scars occurs. This is a rare form of the disease. It occurs due to blood clots entering the abdominal cavity. This type of pathology is treated by the surgical method.
Endometriosis provokes the occurrence of inflammation in the peritoneum. It disrupts the work of internal organs. It affects the walls of the uterus. Causes the formation of adhesions and nodes. This disease is the cause of infertility.
The most common causes of this disease include:
- hormonal disorders;
- immune malfunctions;
- heredity;
- stress;
- various neuropsychological disorders.
Symptoms of the disease do not appear immediately, but only at a late stage of development:
- The uterus increases in size up to six weeks of pregnancy. It takes a round shape.
- There is a heaviness in the lower abdomen.
- Disturbing pain in the abdomen. They are felt both during menstruation, and during urination, defecation, as well as during intercourse.
- Infertility occurs.
- Menstrual irregularities occur.
The disease in all ladies proceeds differently. Based on the results of the tests, an experienced gynecologist can easily make an accurate diagnosis and prescribe the appropriate treatment, prescribe a cure for endometriosis, which will prevent the occurrence of relapses.
Methods of treating pathology
What drugs to treat endometriosis? This question is hard to answer. Most doctors agree that the treatment of pathology should be comprehensive. It should be treated not one single organ, but the whole body.
Before prescribing a medicine for endometriosis, the doctor takes into account the neglect of the disease, the patient’s immunity, the characteristics of the disease, complications, localization and spread of the process.
Endometriosis is treated in three main ways, these are:
- combination therapy;
- surgical intervention;
- conservative treatment method.
Endometriosis can be cured without surgery only in rare cases. Conservative therapy is resorted to only with:
- infertility
- asymptomatic course of the disease;
- reproductive age of ladies;
- adenomyosis.
In all other cases, gynecologists advise a surgical method of treatment. Depending on the severity of the disease, the uterus will persist or be removed completely.
With the conservative surgical method, damaged areas are removed operatively, and unpigmented, inaccessible and microscopic foci are treated with the medication method. After treatment of endometriosis, patients safely become pregnant, have a baby and give birth.
Medicines used in the treatment of pathology
The gynecologist selects the medicine for endometriosis, based on the severity of the disease. Used drugs use:
- to reduce the production of sex hormones;
- from uterine bleeding;
- to eliminate a pain symptom and other negative manifestations;
- before surgery;
- during rehabilitation, after surgery.
Medicines for endometriosis should be taken only according to the schedule prescribed by the doctor. You should strictly adhere to the recommended duration of the course, since many drugs, with longer use, can cause many side effects.
What drugs to treat endometriosis? Such a question is often asked by women who have discovered this pathology. As a rule, in the treatment of this disease, drugs of several groups are used, these are:
- Gonadotropin releasing hormone agonists. Medications are hormonal. Reduce the amount of estrogen production. Can be used both in tablet form and in the form of injections. Enter the body into artificial menopause. Menstruation ceases to come due to lack of estrogen. Against this background, the endometrium also stops growing. The lesions regress. Such drugs should be treated for about six months. Longer therapy can lead the body to an early menopause. The best drugs for endometriosis in this group are Zoladex, Diferelin, and Buserelin preparations.
- Antigestagens, inhibitors of the production of gonadotropic hormones. Drugs in this category inhibit the production of luteinizing, follicle-stimulating hormones. Suppress progesterone production. The drugs are released in the form of tablets and capsules. Medications give pronounced side effects. The most popular medicines are Mifepristone and Danazol.
- Gestagens. Another group of medicines used in the treatment of endometriosis. Progesterone tablets stabilize the menstrual cycle, lengthening the second phase. The most effective drugs in this category include Norkolut, Dufaston, Utrozhestan. Medications can be prescribed not only in the form of tablets, but also in the form of injections.
- Combined oral contraceptives. They include estrogens and gestagens. Stimulate the production of female sex hormones. Stabilize development and prevent endometrial growth. Drugs in this category have been drinking for about six months. Popular: “Janine”, “Klayra”, “Diane-35”, “Jess” and “Yarina”.
Intrauterine devices can be used to treat the disease . The most popular is Mirena. Sometimes they use medicines containing male hormones, androgens. One such drug is Methyltestosterone. In addition to these drugs, non-hormonal medications can also be used in the treatment of endometriosis.
Treatment of endometriosis is complex and long, at least six months. To achieve a good result, all doctor's instructions should be followed. Do not violate the treatment regimen. The disease is very serious and can progress, so self-medication in this situation should be excluded.
Combined oral contraceptives
In the treatment of endometriosis in young women, low-dose oral contraceptives are widely used. They minimize the effects of male hormones. At the time of taking the tablets, the sebum of the skin and hair decreases in women, the amount of acne is noticeably reduced. This therapy is often carried out in conjunction with surgical intervention. If the operation is not done, then the medicine for uterine endometriosis is drunk for 6-9 months.
The following medicines are considered the most effective:
- "Silhouette". These are hormonal tablets of the combined type. They have antiandrogenic and anti-inflammatory properties. The active substance is ethinyl estradiol. The medicine “Silhouette” for endometriosis is taken daily, one tablet per day. The therapeutic course for at least three weeks. The cost of the drug is about 700 rubles.
- Norkolut. The drug is very rapidly absorbed into the gastrointestinal tract. Valid two hours after administration. Contains the active ingredient - norethisterone. The drug is taken from the fifth to the fifteenth day of the menstrual cycle. The daily norm is 5 ml. The course lasts six months. The price is 350 rubles.
- "Yarina." The medicine has antiandrogenic properties. Reduces the activity of the sebaceous glands. Reduces the amount of acne. A medicine for endometriosis is drunk every day for three weeks. The duration of admission is regulated by the doctor. The drug costs about 500 rubles.
- "Regulon." It is a contraceptive multiphase drug. It contains two active ingredients, these are ethinyl estradiol and desogestrel. Pills activate the secretion of sex hormones. They are drunk daily. The course is 21 days. The price of the drug is about 300 rubles.
- Klaira. Combined contraceptive type. Its action is based on the properties of two active substances: dienogest and estradiol valerate. The medicine changes the quality of the cervical fluid, due to which ovulation processes are suppressed. The course is 28 days. There is a drug in the region of one thousand rubles.
- Novaring. The drug is presented in the form of a special ring for the vagina. It contains two active components - this is etonogestrel and ethinyl estradiol. The medication is injected into the vagina for 21 days. The price is 380 rubles.
- "Jess." It is characterized by antiandrogenic properties. Active substances: drospirenone and ethinyl estradiol. It is taken orally. The duration of treatment is 28 days. There are tablets in the region of 1000 rubles.
- Novinet. Suppresses ovulation. It stabilizes the quality of cervical mucus. Contains ethinyl estradiol with desogestrel. The medicine is taken for three weeks, then take a 7-day break. After which the treatment is continued. The price is 600 rubles.
- Logest. It contains ethinyl estradiol in combination with gestodene. Suppresses ovulation processes. It normalizes the state of cervical mucus. The tablets are taken orally for 21 days. Then they take a break for a week. If necessary, continue treatment.
These drugs should be taken at the same time. If the drug is prescribed without a seven-day break, then menstruation does not come.
"Janine" with endometriosis
"Janine" is the most popular cure for uterine endometriosis. In patients who took this medication, the disease regressed for a long time. Well-being has noticeably improved.
"Janine" refers to the drugs of the latest generation. It is a low-dose hormonal medicine. Contains dienogest in combination with ethinyl estradiol. It is quickly absorbed and immediately begins to act. It inhibits the production of hormones, as a result of which the amount of estrogen is reduced. Pills prevent the onset of ovulation. When used, you can not get pregnant. Another drug reduces the contractility of the fallopian tubes. It complicates the promotion of the egg.
Gynecologists prescribe "Janine" to prevent the growth and development of the focus of the disease. To suppress pain and inflammation.
This medicine for endometriosis has only positive reviews. Ladies note that against the background of taking this drug, they lost pain, the condition of nails and hair improved, the skin became cleaner. The drug also helped women with hirsutism. The fairer sex recommend these pills to those who have an excessive amount of androgens in the body.
"Janine", like other similar contraceptives, is indicated for endometriosis at the initial stage of development. The drug can be prescribed before surgery and after surgery, to prevent relapse.
To achieve the result, drink "Janine" should be at least nine months, continuously. The drug is prescribed strictly according to indications and after a detailed examination of the woman. The medicine has contraindications and can cause side effects, so you should not take it without a doctor’s prescription. The cost of "Zhanin" varies within 800 rubles.
In order to reduce the negative effect of hormonal drugs for endometriosis, hepatoprotectors, such as Karsil or Essential, are additionally prescribed. Enzymes (Pancreatin, Creon) may be prescribed. To protect the stomach, they recommend sea buckthorn oil, Gastal, Methyluracil and others.
Gestagens
What drugs are prescribed for endometriosis? In the treatment of this disease, a variety of drugs can be used, including gestagens. We already mentioned these funds, but it is worth considering this group of drugs in more detail. These drugs are substitutes for progesterone, a female hormone that is produced by the corpus luteum of the ovary. This substance is synthesized in the area of the bursting follicle, after the ovulation process. It positively affects the hormonal background and improves the structure of the endometrium.
The best drugs for endometriosis in this group include the following drugs:
- Dufaston. The drug is prescribed to drink from 5 to 25 days of the menstrual cycle. Then they take a week-long break and resume taking the medicine. Daily dose of 10-20 mg.
- Norethisterone. The treatment regimen is similar to Dufaston. The maximum allowable daily intake of 5 mg.
- Mirena. Intrauterine device. The active substance is levonorgestrel.
- "Utrozhestan". The drug is prescribed from 16 to 25 days of the menstrual cycle. The treatment course can last up to 9 months. Judging by the reviews, it helps to cope with the pathology.
Of particular interest is the cure for endometriosis Vizanne. It is used most often. The drug showed just an excellent result in the treatment of this disease. The medicine is taken one tablet a day, for about a year.
The drug reduces the lesions and reduces the number of vessels that provoke the appearance of endometriosis, which significantly reduces the trophic disease. Side effects when taking "Byzantine" are rare. As a rule, this is an upset of the gastrointestinal tract, pain in the abdomen, headache, skin rashes and depression.
The medications for myoma and endometriosis are the same. With the nodular form of fibroids, gynecologists usually prescribe Dufaston. "Vizanne" is prescribed in the advanced stage of the development of the disease.
Spiral "Mirena"
What drugs effectively treat endometriosis? These are the drugs that have been described above. Among them, the last place is occupied by the intrauterine device Mirena.
The therapeutic system inhibits endometrial growth. Contains levonorgestrel, a substance that is an analogue of the female hormone - progesterone.
The spiral affects the woman’s body locally, as a result of which less hormones enter the body than with the use of tablet preparations.
Mirena normalizes the menstrual cycle, reduces the duration of menstruation and the amount of bleeding. It removes pain.
Endometriosis in the mild stage of development can be easily treated with this medication. At the beginning of the use of the spiral, spotting may be observed. But, after some time, the situation is radically changing. The cycle is leveled. And menstruation becomes less long and not so plentiful. In some women, after the installation of the spiral, menstruation ceases altogether. With endometriosis, this is a positive point.
Antigonadotropic drugs
About what medications to drink with endometriosis says a gynecologist. As a rule, if the disease is not started, then medications that stop the production of pituitary hormones are prescribed for its treatment. After all, it is they who actively stimulate the work of the ovaries. The synthesis of LH and FSH is inhibited.
We have already mentioned the list of the most popular drugs of this group, but it is worthwhile to dwell on them in more detail. When using these drugs, the patient has an artificial menopause and the production of estrogen is reduced to a minimum.
The best drugs in this group include:
- "Buserelin." Available as a spray. It is applied for about 4-6 months. Three instillations are administered daily in each nasal passage.
- Buserelin Depot. Available in ampoules. It is used as an injection. The drug is administered once a month, intramuscularly.
- Zoladex. The medicine is made in the form of subcutaneous capsules. It is injected under the skin every 28 days.
- Danazol It is made in capsules for oral administration. Refers to antigonadotropins. It is characterized by a slight anabolic effect. . . . 400 . , .
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If there are certain indications, antibiotics may be prescribed to treat endometriosis. But these medicines are rarely used, as they stimulate the development of the disease and provoke the growth of the endometrium.
Herbs for Endometriosis
Medicinal plants are indispensable assistants in the treatment of pathology. Reviews of women say that with the constant use of herbs can provide a lasting result. So, the plants that are used for endometriosis include:
- boron uterus;
- red brush;
- nettle;
- fees with elderberry, raspberry and blackberry;
- celandine.
From herbs, you can prepare decoctions, make alcohol tinctures and douching.
Do not forget to consult a doctor before using medicinal plants. And do not replace the herbs prescribed by the gynecologist with herbs. So you can completely start the disease and provoke the occurrence of complications, serious health problems.