“Triampur” is a combined therapeutic agent, the effect of which is explained by the action of the components included in it. It has diuretic and hypotensive properties. It has in its composition hydrochlorothiazide, which is a diuretic with medium strength and at the same time a substance that promotes the preservation of potassium.
The composition and form of release of the drug "Triampur"
The instruction informs that one tablet of the drug contains
active substances in the composition:
- hydrochlorothiazide in an amount of 12.5 mg,
- triamteren - 25 mg;
excipients:
- lactose monohydrate;
- potato starch;
- polyvidone K25;
- highly dispersed silicon dioxide;
- sodium starch glycolate;
- magnesium stearate.
Tablets are packaged in 50-pack vials.
Indications for use of the drug "Triampur"
The instruction indicates the use of the drug for arterial hypertension, edematous syndrome of various origins (for chronic heart failure, pathology of the kidneys, liver).
Quite often, in practice, the drug “Triampur” for children under one year of age is prescribed as a diuretic for ICP (increased intracranial pressure).
Contraindications
It is not allowed to apply when:
- hypersensitivity;
- renal failure;
- anuria;
- acute glomerulonephritis;
- Severe violations of the liver;
- Impaired electrolyte metabolism disorders: hypokalemia, hyperkalemia, hypercalcemia, hyponatremia;
- hypovolemia.
The use of the drug "Triampur"
The instruction prescribes to swallow the drug after eating, do not chew and drink with a small amount of liquid. Doses are determined by the doctor for each patient individually. For adults and children weighing more than 50 kg, the estimated therapeutic dose is -2-4 tablets - two doses / day. As a maintenance therapy - one tablet / day.
Pregnancy and lactation
The medicine can not be used during pregnancy, and breastfeeding should also be stopped for the period of treatment.
Interaction with other drugs
Antihypertensive and diuretics , barbiturates, tricyclic antidepressants, vasodilators, phenothiazines stimulate the hypotensive effect; and NSAIDs, on the contrary, weaken.
The medicine "Triampur" (the instruction emphasizes this) weakens the effect of antigout, antidiabetic drugs, adrenaline and norepinephrine. But it enhances the toxic effect of lithium, side effects of salicylates on the central nervous system, curariform relaxants, glycosides, and cytostatics.
Side effects
“Triampur” can cause negative effects in the nervous system with symptoms of ataxia, drowsiness, headache, nervousness, etc.
In the cardiovascular system, its use sometimes causes ECG changes, palpitations, lowering blood pressure, orthostatic hypotension , etc.
Side effects in the digestive tract are manifested in the form of nausea, vomiting, diarrhea, sometimes - pain in the epigastrium, and in some cases - jaundice, hemorrhagic pancreatitis , etc.
In the metabolic process, substances are possible
- violation of electrolyte balance, metabolic acidosis;
- increase in cholesterol, glucose, triglycerides;
- dehydration, hypovolemia, etc.
The purpose of the drug "Triampur" for children: reviews
Despite the fact that the instruction does not recommend the use of the drug in children under 18 years of age, in modern medical practice, this medicine is often used to treat ICP in children under one year of age.
After analyzing a large number of reviews on the use of the drug "Triampur" in children under one year of age, we can come to the following conclusion. In the vast majority of cases with ICP in children, this drug has proven to be a very effective tool. There are a significant number of positive reviews by mothers about the use of this medicine in the treatment of children. But since this drug has a rather large number of contraindications, as well as no less than the number of possible negative effects, it should be used only after the appointment of a doctor. When the first signs of side effects appear, you should immediately consult a doctor.