Pheniramine maleate is an active substance in many modern drugs. As a rule, it is used to stop or partially suppress an allergic reaction (antihistamine).
Pheniramine maleate: action and properties of the substance
Penetrating into the body, the substance spreads along with the flow of blood. Its maximum concentration is noted an hour after administration.
Pheniramine acts on the medulla oblongata. It quite quickly blocks histamine and muscarinic receptors, which explains its properties. This component has persistent anti-allergic properties. In addition, when properly selected dosage reduces the phenomenon of exudation.
In most cases, the effect of taking the drug lasts no more than a day, but this indicator may vary depending on the individual characteristics of the patient's body. Large drugs are often excreted by the kidneys - partly in an invariable form, and partly in the form of metabolic products.
Pheniramine maleate: a description of the drugs
As already mentioned, this substance is an integral part of many drugs. In most cases, these are allergy medications. In addition, it can be found in drugs such as Fervex, Teraflu, Rinzasip and others.
Pheniramine maleate is a component used in the manufacture of anti-colds and acute respiratory diseases. Part of its role is to reduce the amount of mucus secreted, and partly to suppress the allergic reaction that inevitably occurs as a result of taking medication. It is thanks to this substance that nasal congestion in colds is reduced.
Pheniramine Maleate: When Used
This substance has a huge list of indications for use. It is primarily used for allergic conjunctivitis and a runny nose. It is effective in the treatment of dermatitis and neurodermatitis. It quickly relieves allergic puffiness, prevents the appearance of urticaria.
This tool is also used in the presence of skin itching. It is effective for insect bites, as it stops the development of an allergic skin reaction. Pheniramine is included in the composition of drugs used for first-degree burns.
In combination with other drugs, the substance is used in the presence of general malaise after radiation therapy.
Pheniramine maleate: dosage and interaction with other drugs
The dosage should be determined only by the attending physician, based on the patient's condition and the presence of contraindications. As a rule, preparations containing pheniramine have their own recommended doses.
Pheniramine maleate interacts with certain medications. For example, it enhances the effect on the body of barbiturates and antidepressants. In some cases, the substance is able to inhibit the action of anticoagulants.
Drugs containing pheniramine are not recommended for use with hormonal contraceptives, since in this case its antihistamine properties can be inhibited. In no case should you drink alcohol during treatment with pheniramine.
Pheniramine maleate: contraindications and side effects
This substance is quite easily perceived by the human body, especially in small quantities. Nevertheless, there are some contraindications, such as, for example, the patient's individual sensitivity to pheniramine.
It is also not recommended for people with angle-closure glaucoma (due to increased intraocular pressure) and men with prostatic hypertrophy.
As for the side effects, they are mostly explained by effects on the nervous system. A person can feel tiredness, drowsiness, weakness, and a slowdown in psychomotor reactions. With an overdose in children, hallucinations and confusion can occur. Occasionally, there is a dry mouth and a delay in urine output.