Offlocaine ointment is produced by Darnitsa and is part of the group of antibiotics and chemotherapeutic agents for treating skin diseases. The drug quickly gained recognition among patients and doctors due to its high efficiency combined with affordable cost.
Consider in more detail information about the tool: its composition, indications and contraindications for use, possible side effects and so on. Special attention will be given to reviews about the drug.
basic information
“Oflokain-Darnitsa” (oflokainovy ointment) contains ofloxacin and lidocaine hydrochloride as the main active substances. Some auxiliary components, such as proxanol-268, are also present in the product. macrogol-1500, macrogol-400, macrogol-6000, purified water, propylene glycol.
Oflocaine ointment is white in color and has a slight specific smell.
The drug goes on sale in tubes of 15 or 30 g. Instructions for use, which contains all the necessary information, is additionally attached to each package.
The shelf life of the product is two years. It must be stored in its original packaging at a temperature of 8 to 26 degrees.
Pharmacokinetics
When applying the drug with lidocaine and ofloxacin to healthy skin, its components practically do not enter the systemic circulation. If there is a violation of barrier functions in the form of wounds (burns, cuts, etc.), about 3% of the used dose of the active substance enters the bloodstream. Its maximum concentration in the body is observed 3-4 hours after application. After 6 hours, ofloxacin is not detected in the blood.
Pharmacodynamics
Oflocaine ointment is distinguished by both antimicrobial and anesthetic effects due to the presence of ofloxacin and lidocaine in its composition.
The first shows excellent effectiveness in the fight against aerobic gram-negative microorganisms (one of which is Helicobacter pylori) and aerobic gram-positive bacteria (streptococci, staphylococci and so on). However, there are some types of pathogens of inflammation that are completely insensitive to the effects of ofloxacin. These include fungi, pale spirochete, viruses, anaerobic bacteria, and so on.
Anesthetic effect is achieved due to the properties of lidocaine. It prevents the conduction of impulses along nerve fibers by reducing the permeability of sodium ions and stabilizing the neuronal membrane. The substance is characterized by a short latent period and the subsequent rather long period of action, which ranges from 1 to 3 hours. In this case, the component does not irritate the tissue and is able to dilate blood vessels.
The polymer hypersmolar base of the product provides the movement of water in the wound towards the ointment. Due to this, there is a decrease in edema in the area of damaged tissue and the removal of its purulent-necrotic contents.
Indications for use
In what cases can an offlocaine ointment be used? Its use is provided if the patient has:
- purulent-inflammatory skin diseases that were caused by bacteria;
- complicated infected wounds of the first phase of different locations and origin (wounds after surgical manipulations and treatments, trophic ulcers, amputation stumps of limbs, bedsores, phlegmon and abscesses of the maxillofacial region, postoperative fistulas and complicated wounds, and so on).
In addition, Oflokain-Darnitsa can be used to prevent and treat purulent complications and suppuration of wounds resulting from a burn.
Contraindications
There are some cases during which you can not use a remedy such as ocular ointment for treatment. The instruction for the drug suggests that the ointment is strictly forbidden to use if the patient has hypersensitivity to its components, as well as to patients under the age of 15.
In addition, the tool is not recommended for use in the treatment of pregnant and lactating women, as well as in the second phase of the wound process.
Mode of application
How should the oflocaine ointment be used correctly? Instructions for use will answer this question.
It’s worth starting with the fact that the product is intended exclusively for external use. It is used after all necessary manipulations in the form of cleaning and treating the affected area.
The method of application of the drug depends on the type of wound. For example, when treating burns, the ointment should be applied directly to the affected area or a sterile gauze dressing, which then needs to be applied to the affected skin. In this case, the frequency of use can be both daily and several times a week, depending on the amount of purulent discharge.
To get rid of purulent wounds, an ointment is preliminarily lubricated with a tampon, and in case of lesion of the fistular passages, special turundas should be used. In these cases, the drug is used once a day.
The total treatment time can only be determined by a doctor. He will take into account the dynamics of cleansing the wound from purulent discharge and the timing of the relief of the inflammatory process.
Oflocaine ointment can also be used to treat dermatological diseases. In this case, the product must be applied with a thin layer on the affected parts of the skin or use applications with gauze bandages 1-2 times a day. On average, such treatment takes up to two weeks.
Overdose and side effects
Cases of overdose have not been identified.
Offlocaine ointment immediately after application to the affected surface may cause a slight burning sensation. If it disappears after a few minutes, drug withdrawal is not necessary.
A side effect from the use of the drug can occur only in the form of allergic reactions, which were due to increased sensitivity and intolerance to its components.
Reviews about the drug
How high is the offlocaine ointment? Patient reviews about her are extremely positive!
One of them helped to quickly cope with suppuration that appeared after infection of the wound, others used it to treat a burn, and still others used it in the postoperative period. In all of the cases described above, oflocaine ointment showed its effectiveness and a quick mode of action.
To summarize
So, we found out that Oflokain-Darnitsa ointment has an excellent disinfecting and analgesic effect. All information in the article was provided for informational purposes only. The use of any medication should first be agreed with your doctor.
Do not self-medicate and be healthy!