Various infectious diseases, unfortunately, can be very dangerous for humans. Often such ailments are rapid and lead to the development of all kinds of serious complications. They treat diseases of this variety using mainly antibacterial agents. There are, of course, many such drugs produced by the modern pharmacological industry. And one of the most effective means of this group is considered to be Rovamycin. The active substance in the composition of such tablets may be included in different dosages. Further in the article, we will consider how Rovamycinum is supposed to be taken (3 million me).
Release form and composition of the drug
In pharmacies and clinics, this modern medicine is delivered under the trade name Rovamycin. In Russia, such a drug is produced mainly only in the form of powder and tablets. Occasionally, a solution of this drug for injection can also be found on sale. In European countries, this tool is supplied to the market in a wider range in terms of release forms. Moreover, the international name of this drug is “Spiramycin”.
In our country, the most popular form of “Rovamycin” is exactly 3 million me tablets. Less commonly on sale you can find the drug at 1.5 million me. In any case, the main active substance of this medicine is the natural antibiotic spiramycin. Also, the composition of the tablets “Rovamycin” 3 million me and 1.5 million me includes such additional substances:
- colloidal anhydrous silica;
- magnesium stearate;
- corn starch;
- cellulose, etc.
The drug is supplied to the market 3 million me in cardboard boxes in plates of 10 tab. The 1.5 million me option is packaged in the same way, but at 8 tab. The color of the tablets of this medicine is white with a cream tint. Their shape is biconvex. On one side of the 3 million me tablets, there is an ROVA 3 engraving.
What effect does the drug have on the human body
Rovamycin belongs to the antibiotics of the macrolide group. Once in the human body, its active substance penetrates primarily into the phagocytes and begins to accumulate in them. Its concentration in immune cells in the body during treatment can be very large. This explains the high effectiveness of Rovamycin on harmful intracellular bacteria. The therapeutic effect of this drug is manifested in most cases very quickly. In the human body, this drug almost instantly destroys the strains of Streptococcus, Branhamella catarrhalis, Bacillus cereus, Campylobacter, Coxiella and many others.
This remedy helps patients in this way quickly. But some types of bacteria to this medicine, unfortunately, can be resistant. Therefore, taking this drug uncontrollably is by no means impossible. This can lead to the fact that time will be lost and the disease will go into the difficult stage. Rovamycin resistant bacteria are, for example, Enterobacteria, Nocardia asteroids, Fusobacterium, etc.
This drug is excreted from the human body mainly with bile. But some of it during the course of treatment can also be found in the urine and feces of the patient. The half-life of “Rovamycin” from plasma is 8 hours.
Drug features
Rovamycin is absorbed quite well in the patient’s body, but, unfortunately, not completely. At the same time, eating does not affect the degree of absorption of this medicine. That is, you can take the drug both before meals, and after or during it.
A feature of this tool, among other things, is that in the body of a pregnant woman it is not able to penetrate the placental barrier. That is, this drug belongs to a few antibiotics, which can be treated, including when carrying a child. However, Rovamycin, unfortunately, can still be found in breast milk. That is, taking it during lactation is not worth it.
Indications
Doctors can use this drug to treat a wide variety of infectious diseases caused by bacteria that are sensitive to it. Of the ENT ailments, Rovamycinum (3 million units) usually helps a lot with:
Also, this medicine can be prescribed to patients with skin infectious diseases:
- ectim;
- dermatocellulitis;
- erysipelas;
- dermatosis, etc.
According to the instructions for use, "Rovamycin" (3 million me) can be prescribed for the treatment of the following ailments of the respiratory system:
- pneumonia;
- chronic bronchitis (with exacerbations).
Effectively, “Rovamycin” acts in some diseases of the reproductive system. Also, this medicine is often prescribed to pregnant women with the development of toxoplasmosis in them.
In addition to the treatment itself, in some cases, this drug can be prescribed to patients and for the prevention of diseases. For example, in this way it is often used when there is a risk of staphylococcal meningitis in a person. This serious purulent disease, unfortunately, often develops in young children and is characterized by a rapid course. Of course, sometimes such meningitis is also diagnosed in adults.
What contraindications exist
This medicine usually does not have too serious negative effects on the body of patients. However, Rovamycinum (3 million me) can be prescribed to patients, like any other antibiotic, of course, not in all cases.
Contraindications to the use of this medication are:
- hypersensitivity to any of its components;
- deficiency of the enzyme glucose-6-phosphate dehydrogenase (there is a risk of acute hemolysis);
- the risk of lengthening the QT interval, both acquired and congenital.
Since this drug passes into breast milk, as already mentioned, it cannot be used to treat nursing women. For such patients, doctors usually replace it with an analogue. In some cases, if necessary, treatment with this particular tool, the child can be transferred to artificial feeding.
In which cases it can be prescribed with caution
Only a very small part of the active substance “Rovamycin” (3 million IU) is excreted from the human body with urine. Therefore, unlike some other antibiotics, dose adjustments of this drug, if the patient has any problems with the kidneys, usually do not.
When diagnosing certain types of diseases in patients, this remedy can be prescribed to them with caution. Most often, under the special supervision of doctors are patients undergoing treatment with "Rovamycin" (3 million me) with obstruction of the bile ducts. Also, with great care, this medicine is prescribed for patients with liver problems.
Dosages of the drug for adults
Of course, the treatment regimen with Rovamycin 3 million me, like any other antibiotic, should be developed by the attending physician. Dosages of this drug depend on this particular disease and the characteristics of the patient's body.
Most often, this drug (3 million me) is used by patients in the treatment of infectious diseases 2-3 times a day. In this case, each time patients take 1 tablet. For the prevention of staphylococcal meningitis, “Rovamycin” (3 million me) is used in most cases, one tablet in 2 divided doses with a break of 12 hours.
Instructions for "Rovamycin" (3 million me): dosages for children
It is possible to treat various kinds of infectious diseases using this drug not only in adults. For children, this remedy is also prescribed quite often. Of course, the dosages used to treat such patients are reduced.
Typically, for infectious diseases, children are prescribed no more than 150-300 thousand me of this drug per kilogram of body weight per day. Moreover, such a dose is necessarily divided into two to three doses. At the same time, children can drink “Rovamycin” in an amount of not more than 300 thousand me per day. That is, for such patients, tablets of 3 million me have to be divided into several parts.
Prevention of meningitis using Rovamycinum (3 million), according to the instructions, can, of course, be carried out for children. In this case, for small patients, doctors usually prescribe 75 thousand me of this medicine per day in two doses with a break of 12 hours.
What side effects can cause
Despite the fact that Rovamycin does not belong to the group of very heavy drugs, in some cases it can cause negative reactions in patients undergoing treatment. Side effects in patients drinking this medicine are sometimes observed as follows:
- nausea, diarrhea, vomiting;
- pseudomembranous colitis;
- paresthesia;
- anemia;
- urticaria, itching.
In very rare cases, after taking Rovamycinum (3 million me), anaphylactic shock develops in patients. This, in turn, unfortunately, can lead to death.
What will happen in case of an overdose of the drug
The use of "Rovamycin" allows you to get rid of many, often even quite dangerous infectious ailments. However, drinking this medicine should, of course, strictly at the dosages prescribed by the doctor. If the patient takes too many of these pills, he may have serious health problems.
In case of an overdose of Rovamycin, the patient is advised to determine the QT interval. In particular, taking too much of this drug can be especially dangerous for patients with:
- hypokalemia;
- congenital lengthening of QT.
An overdose of “Rovamycin” is also of great danger for people undergoing treatment using agents that cause ventricular flutter or prolong the QT interval.
Analogues of the drug
In some cases, doctors may prescribe other medicines with a similar therapeutic effect instead of Rovamycinum. The most popular synonyms for this medication (drugs with the same active substance) are:
- Spiramycin-Vero;
- Spiramisar.
According to the spectrum of activity, the analogue of Rovamycinum (3 million me) is Macropen. The main active ingredient of this drug is midecamycin. Like Rovamycinum, this antibiotic belongs to the macrolide group. This medication can be prescribed to both adults and children. However, in case of renal failure, unlike Rovamycinum, it cannot be used to treat infectious diseases. For pregnant and lactating women, this medicine may be prescribed with caution. In such cases, the doctor determines what is more dangerous for the child - the illness of the mother herself or the harm from getting an antibiotic into her body.
Reviews on "Rovamycin" (3 million units)
The advantages of this drug are primarily attributed to patients who treat various infectious diseases effectively. From a cold, for example, judging by the reviews available on the Web, this tool helps to get rid of in just a couple of days. Of course, one of the main advantages of Rovamycin, according to patients, is that it, unlike many other drugs, can be taken during pregnancy. Judging by reviews from the Internet, the treatment of this medicine in the future does not affect the health of children in any way.
Patients consider its rather high cost as a certain disadvantage of Rovamycinum. However, doctors, like many patients, highly recommend not changing this drug to any other, cheaper antibiotics (and especially during pregnancy). The price of “Rovamycin” is high, but it has practically no toxic effect on the human body. In addition, and side effects this remedy, judging by the reviews of patients, is quite rare.