Cases of interstitial nephritis are considered very common in modern medical practice. A similar disease is accompanied by inflammation of the intermediate tissues of the kidney. But unlike other nephritis, damage to interstitial tissues is not directly related to the activity of pathogenic microorganisms.
The main causes of interstitial nephritis
As already mentioned, such a disease is rarely associated with infections. In this case, the inflammatory process is autoimmune and is an allergic reaction caused by taking a number of drugs.
At the beginning of the twentieth century, it was noticed that inflammation of the tubules and intermediate tissues of the kidney most often occurs in patients taking pain medications. In particular, drugs containing paracetamol, as well as phenacetin, can be attributed to potentially dangerous drugs. Long-term use of aspirin leads to approximately the same result.
In addition, taking certain antibiotics can cause interstitial nephritis. The group of such drugs includes Ampicillin, Penicillin. In some cases, symptoms of an allergic reaction are observed with the use of diuretics and sulfonamides.
Symptoms of Interstitial Jade
Unfortunately, no one can be completely insured against such a disease, since it is often diagnosed in both children and adults and elderly patients. The first signs, as a rule, occur 2-3 days after the start of taking certain drugs.
Acute interstitial nephritis begins with weakness, headaches, and unpleasant pulling pains in the lumbar region. In the future, there is a fever, aches and pain in the body. Patients complain of constant drowsiness, fatigue. Along with this, nausea and loss of appetite appear. In some cases, kidney inflammation is accompanied by the appearance of a skin rash, as well as joint pain.
Due to the inflammatory process and damage to the renal tubules, the excretory system can no longer perform its main functions. Therefore, the disease is characterized by pain during urination, as well as hematuria. In especially severe cases, the daily amount of urine excreted significantly decreases up to anuria.
Chronic interstitial nephritis, as a rule, occurs against the background of a constant, daily intake of small doses of analgesics. This form of the disease may have a blurred clinical picture, which makes the diagnosis process more difficult.
Interstitial Jade Treatment
In fact, therapy in this case directly depends on the cause of the disease. Of course, first of all, you need to determine allergen drugs and stop taking them. And if antibiotics are canceled quite easily, then giving up pain medications can be much harder, especially if the patient has become dependent on medications. In this case, a consultation with a psychiatrist is necessary.
At the time of treatment, the patient is prescribed a diet based on food rich in vitamins and minerals. This will help repair damaged tissue and normalize electrolyte balance. In some cases, hormonal anti-inflammatory drugs are indicated.
It is worth noting that such an inflammatory process, especially in the absence of timely treatment, can lead to the development of renal failure. In such cases, hemodialysis, and sometimes a kidney transplant , is indicated .