The drug "Aprovel": analogue, instructions, indications

Aprovel is usually prescribed to people suffering from hypertension. In patients, this medicine is considered the best among these. The fact is that Aprovel, the use of which is shown, of course, by no means to all patients, effectively regulating blood pressure, practically does not affect cardiac activity. Very often, therefore, it is prescribed to those patients who should not drink antihypertensive drugs.

From the article presented below, our reader will find out what the instructions for use are for the Aprovel preparation . Analogs of this medication will also be considered in detail.

aprovel analog

The composition of the drug

This product is produced mainly in oval tablets. There are also Aprovel solutions on the market for intravenous infusion. The main active ingredient of the drug is irbesartone. The composition of the drug also includes:

  • lactose monohydrate;

  • corn starch;

  • croscarmellose sodium;

  • silica;

  • poloxamer 188;

  • colloidal water;

  • microcrystalline cellulose;

  • magnesium stearate.

Aprovel tablets weigh 150 mg each. You can recognize them by engraving - a heart on one side and numbers 2772 on the other. Also on the market are sometimes found tablets "Aprovel" 300 mg each.

aprovel instructions for use analogues

pharmachologic effect

Once in the patient's body, the drug "Aprovel" begins to actively influence the receptors of type 2 angiotensin. The latter are primarily responsible for the contractility of the vessel walls. Upon contact with them, the angiotensin enzyme causes a narrowing of the lumen of the arteries. As a result, blood pressure decreases.

The main feature of the Aprovel medicine, in comparison with similar ones, is that it does not interact with other enzymes in the body at all. Due to this, the patient taking the drug does not show changes in the blood. In particular, the plasma does not increase the concentration of calcium and various other substances that can adversely affect the activity of the cardiovascular system.

This medicine begins to act approximately 5-6 hours after it enters the digestive tract. The antihypertensive effect when taking Aprovel means develops within 7-14 days. He reaches a peak approximately 6 weeks after the start of treatment.

Indications

Since this medicine is effective, doctors often prescribe Aprovel to their patients. Its use is indicated for diseases such as:

  • essential hypertension;

  • nephropathy in type 2 diabetes mellitus and arterial hypertension.

In the latter case, “Aprovel” is prescribed by doctors usually as part of complex antihypertensive therapy. Doctors noticed that this medicine is able to beneficially affect the renal activity of patients with diabetes.

aprovel application

Analogues of the drug

The patients' Aprovel medicine deserved good reviews. Many believe that today it is the best tool in their group. But unfortunately, you can not always find it in a pharmacy. In the absence of this drug on sale, of course, you have to use its substitutes. If necessary, you can drink an analog instead of the Aprovel medicine:

  • Ibertan.

  • Irsar.

  • "Converium".

  • Firmast.

Sometimes instead of this medicine, patients are also prescribed “Lozap” or “Valz.” The generic of this drug “Irbesartan” (with the same composition, but not branded) is also on sale today.

Ibertan

This is a fairly effective analogue of Aprovel 150 mg and 300 mg. The main active ingredient in it is also rbesartan. Ibertan is available in tablets of 75, 150 and 300 mg. The pharmacological effect on the patient’s body, he has exactly the same as "Aprovel." It differs from this medicine “Ibertan” only in that it contains other additional substances.

The medicine "Irsar"

The composition of this drug also includes rbesartan as the main active substance . Irsar is available in tablets. When taking it, the patient is assigned, including a special diet (with a limitation of the amount of salt consumed). Like Aprovel, its counterpart Irsar lowers blood pressure very well . Moreover, he has practically no effect on the patient’s cardiac activity.

aprovel instruction

Firmast and Converium

These medicines can also replace the Aprovel drug . The analogue of his Firmast, as well as Conderium, includes ibersartan. Both of these drugs are available in pill form.

Means "Lozap" and "Valz"

The medicines Firmasta, Converium, Irsar and Ibertan are synonymous with Aprovel, because they have a similar composition. The drugs “ Valz” and “Lozap”, in fact, are precisely its analogues. The active substance is different for them. " Valz" is produced on the basis of valsartan, and "Lozap" - potassium losartan. However, these drugs reduce the pressure as effectively as Aprovel.

Manufacturers and prices

The drug “Aprovel” is produced by the French pharmaceutical companies Sanofi winthrop industrie and Sanofi-Aventis. It is worth packing such a medicine from 14 tablets of 150 mg in the region of 320-350 p. depending on the supplier. For a pack with the 14th tab. 300 mg in pharmacies usually ask for about 450 r.

Sometimes this medicine is sold in packs of 28 pcs. In this case, its cost is 600 p. (for tablets of 150 mg) and 850 r. (300 mg).

Of course, many patients suffering from high blood pressure would like to know if Aprovel has any Russian analogues. Of the substitutes discussed above, only “I Rsar ” is produced in our country . It is produced by the Russian company CanonFarma Production. This medicine is worth about 100 p. for 22 pieces of 150 mg.

aprovel analogues and synonyms

You can find out which companies produce the other drugs considered in the table below.

Analogs "Aprovel"

A drug

Producing country

Company name

Cost

Ibertan

Poland

POLPHARMA SA

202 p.

Converium

Cyprus

"Medochemie LTD"

315 p.

Firmast

Slovenia

KRKA dd

200-300 p.

Lozap

Slovenia

PHARMACEUTICALS

30 tablets of 50 mg - 300 r.

Valz

Malta

Actavis Group h

90 tablets of 80 mg - 700 r.

These are the companies that produce Aprovel substitutes . Russian analogs of it, as you see, are not numerous. The best of them is Irsar. However, the cost of foreign substitutes for this tool is relatively low.

Contraindications

Of course, not all patients can use Aprovel. You can not use this tool, for example, with:

  • renal artery stenosis ;

  • hypo-salt diet;

  • severe vomiting or diarrhea.

It is also contraindicated to drink these pills for children and adolescents under the age of 18 years. Of course, in no case should you take the drug with hypersensitivity to any of its components.

In addition, “Aprovel” is contraindicated for women who carry a baby or breast-feed. Stop taking it should already be planning pregnancy. The above analogs of the drug have the same contraindication. But there is on sale today and one, which is an exception to this rule, is the substitute Aprovel. The analogue of this medicine “Lozap” is allowed to be taken during pregnancy. However, this should be done with great care. And of course, in no case should you appoint him yourself. Drinking “Lozap” for pregnant women should be under the strict supervision of a therapist and gynecologist.

analog aprovel 150

special instructions

Doctors prescribe the drug “Aprovel” to patients, among other things, and in case of violation of the water-electrolyte balance. Before starting to use the medicine, all such problems should be corrected using other medicines.

If the drug is prescribed to a patient with renal failure, the doctor should periodically monitor the level of serum creatine and potassium in his blood. The same applies to individuals with hyperkalemia.

Treatment of patients suffering from coronary heart disease or atherosclerosis using this agent or its analogues should be carried out with strict control of blood pressure.

The medicine "Aprovel": instructions for use

These tablets are prescribed to patients, usually one at a time (150 mg) per day. If necessary, the dosage can be increased to 300 mg. In large quantities, this drug is never prescribed as it is ineffective. If, with increasing the dose to 300 mg, the desired effect does not occur, the patient is usually prescribed an additional medicine from the group of diuretics.

Patients with dehydration or hyponatremia are initially most often prescribed not 150 mg of the drug, but 75 mg. Also, elderly patients are usually treated with this dose.

Side effects of the drug

This is the instruction for use provided for the Aprovel preparation. Its analogs are taken in approximately the same way. This medicine has almost no effect on cardiac activity. However, it should be drunk, of course, only under the supervision of a physician. In some cases, this medicine has various side effects on the patient’s body. For example, the patient may drop too much pressure. In this case, the patient will experience symptoms such as:

  • weakness;

  • nausea and vomiting.

In addition, the uncontrolled use of this drug can lead to serious problems such as impaired liver function (including hepatitis) or kidney problems.

Small dizziness is also what can happen to a patient using Aprovel. Its analogue (practically any) usually causes the same effect. Therefore, during treatment with the use of such funds, you should be as careful as possible when driving a car and when performing work requiring increased attention.

Drug overdose

When exceeding the permissible dosages of the Aprovel medication, patients may experience symptoms such as:

  • tachycardia;

  • bradycardia;

  • collapse.

What rules should be observed by the patient

When taking the drug "Aprovel", the analogues and synonyms of which are numerous, the patient should regularly visit the attending physician. In no case should you change the dosage without consulting a doctor. Replace this medicine with another without consulting a specialist, of course, is also prohibited.

It is advisable to take Aprovel tablets at the same time. Of course, you should not drink this medicine if it has expired or if it was stored incorrectly.

You can drink these tablets both before and after meals. The presence or absence of food in the stomach practically does not affect their absorption into the blood.

Features of the use of substitutes

The analogues of this medicine, considered by us above, made on the basis of the same substance, have similar instructions for use. But some of them need to be drunk nevertheless a little differently than Aprovel. The counterpart of this medicine, Converium, for example, is recommended to be taken in the morning before meals.

Of course, they have completely different instructions for use and substitutes for this drug “Lozap” and “Valz” with another active substance. The average daily dose of the first is 50 mg per day. In patients with chronic heart failure, this medicine is usually prescribed in an amount of not more than 12 mg per day. Valz is most often taken at 80 mg per day.

aprovel reviews analogues

In chronic heart failure, this dose is reduced to 40 mg per day.

What deserved drug reviews

Patients, like doctors, usually praise Aprovel. Reviews (his analogues often do not work so efficiently) from patients, he earned the best. For example, many patients believe that he has much less side effects than the Lozap and Valz medicines. Using this tool, many patients managed to bring pressure to normal literally in a week.

Rules for storing medicine

Thus, we have found out what the “Aprovel” preparation itself is (instructions for use, reviews, analogues). This medicine, as you see, is very good. However, it will work effectively, of course, only if properly stored.

Keep a pack with this product only in a dry room. At the same time, the temperature in the room should not exceed 30 C. Of course, tablets should be stored so that children cannot reach them.


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