The spread of fungal diseases has recently become even more global. It's all about weakened immunity, which allows fungi to multiply freely inside the body. Some people simply live with this problem for several years without resorting to treatment, others try numerous drugs and leave decent amounts of money in pharmacies. In the framework of this article, we will consider the antifungal drug Irunin, which is able to assist in the fight against unpleasant diseases caused by the activity of fungi.
Description
Irunin is a broad-spectrum antifungal antimycotic drug. It is prescribed for acute or chronic forms of diseases that are caused by the activity of various kinds of fungi. Available in the form of capsules for oral administration or vaginal tablets. The latter are used to treat vaginal fungal infections.
The manufacturer "Irunina" is the domestic company Veropharm. The purpose of this medication is possible only after examination and passing tests. If the fungal nature of the disease is revealed, then the patient is prescribed a course of treatment. The drug "Irunin" is a very powerful medicine. Exposure to an organism that has other ailments can be unpredictable. Increasing the dose can cause serious problems with the liver, so consultation with a specialist before taking Irunina is required.
The cost of the drug, depending on the number of capsules, can range from 280-900 rubles. for packaging designed for a full course of treatment. Analogs with an identical active substance are an order of magnitude more expensive.
The active substance of the drug
The active substance "Irunina" is intraconazole. It is a derivative of the substance triazole. Intraconazole is a white to slightly yellow powder. Not soluble in water, poorly soluble in alcohols. Of the auxiliary components, the following can be distinguished:
- Hypromellose. It has a lubricating and softening effect.
- Eudragitus. The substance with which the capsules are coated.
- Nipagin. Dietary supplement E218 with antimicrobial properties. It is used for canning.
- Nipazole. This substance has strong antimicrobial activity and is used as a preservative.
- Gelatin. A soluble capsule is made from it, into which the contents are placed.
- Yellow dyes E104, E110.
There are other antifungal drugs, the main active ingredient of which is intraconazole. The cost of alternative medicines is much higher than the price for the corresponding package "Irunina", and the effect is absolutely the same. Judging by the reviews, Irunin from thrush, nail fungus and other mycoses should be used in combination with other drugs, then the treatment productivity will increase.
The effect of the drug on fungal colonies
The active substance of the drug stops the synthesis of ergosterol - a substance that is necessary for the development and life of fungi. Ergosterol is an active component of the cell membrane of fungi, therefore, in its absence, growth and reproduction become impossible.
Irunin is active against dermatophytes, molds and yeasts. Effective treatment with this drug is due to the interaction of a strong component on fungal cells. Irunin not only relieves the symptoms of the disease, but also completely eliminates the fungal infection if the treatment was carried out correctly and the dosages and terms of treatment were observed.
The drug accumulates in the body in high concentration, the location is affected by the fungus tissue. Complete elimination of the drug from the body occurs only 7 days after the last day of administration.
Forms of drug release
There are only two forms of release of "Irunin": capsules for oral administration and vaginal tablets. Capsules have a smooth yellow shell. The dosage of one capsule is 100 mg. In one box there can be 6, 10 or 12 capsules.
As a rule, the treatment of vaginal fungal infection occurs with the use of suppositories. They are in the form of tablets. The treatment regimen for vaginal tablets differs in dosage from the course of oral treatment. Before taking, read the instructions for use "Irunina".
Irunin is not available in the form of ointments, creams, sprays and other types of solutions. For external treatment of the skin, you need to choose another drug with the same active substance.
Dosage and administration schedule
In order for the treatment to be productive and effective, it is necessary to follow the doctor’s recommendations for the use of Irunin medicine. Here is an example of some diseases of various etiologies and dosage:
- Vaginal candidiasis: 200 mg 2 p. / Day. Course: 1 day.
- Pityriasis versicolor: 200 mg 1 p. / Day. Course: 3 days.
- Dermatomycosis: 200 mg 1 p. / Day. Course: 7 days. Or 100 mg for 15 days.
- Fungal keratitis: 200 mg 1 r. / Day. Course: 21 days.
- Oral candidiasis : 100 mg 1 r. / Day. Course: 14 days.
- Fungal infection of the hands and feet: 100 mg 1 p. / Day. Course: 14 days.
It should be noted that with fungal infections of the nails, therapy is repeated. The general course of treatment can reach several months. In order to completely recover from a fungal infection, it is necessary to strictly adhere to the Irunin schedule. The course must be drunk completely, even if there are no symptoms. Take "Irunin" should be after eating, drinking plenty of water.
Indications for admission
Precisely determine the nature of the disease will help you tests for crops. If the fungal environment of the causative agents of the disease is revealed, then the appointment of the drug is possible. Indications for the use of "Irunin" are the following diseases:
- Genital candidiasis. Thrush is a very common problem, especially for the female. The whole problem is that it is very difficult to get rid of this disease to the end. The causative agent is in the body constantly and is activated under certain conditions. Treatment relieves the symptoms, and then after a while a relapse occurs.
- Fungal infection of the oral cavity. It appears in the form of a light coating on the cheeks, tongue and throat. May cause pain when swallowed.
- Various kinds of mycoses. These are all diseases that are caused by the activity of fungi. Mycoses can be cutaneous and nail.
- Histoplasmosis. This disease affects the lungs and other internal organs. People with weak immunity are especially susceptible to this disease. A neglected stage can be fatal.
- Fungal infection of the skin.
- Onychomycosis. Fungal infection of the nail plates. It appears in the form of detachments of the plate, while the nail changes color to yellow or brown.
This list of indications is contained in the instructions for use of Irunin. To determine the nature of the disease with high accuracy, take tests to identify the type of pathogen.
Contraindications
Irunin is a very powerful drug that can cause serious complications of certain diseases, if any, in the patient. A ban on medication should be introduced if there are the following diseases:
- Hypersensitivity to substances that are present in the composition of Irunin.
- Liver disease.
- Acceptance of other drugs that may reduce the activity of Irunin.
- The first trimester of pregnancy.
- Lactation period.
- Heart failure.
- Admission must be done with caution if the patient is under 18 years old.
Before starting treatment, carefully read the instructions for use of "Irunin" for contraindications. Pregnant women "Irunin" can only be prescribed by a doctor, since the active substance of the drug can have a negative effect on the development of the fetus. When breastfeeding, the drug is contraindicated because of the concentration in breast milk. At the time of taking the medicine, breast-feeding should be abandoned.
"Irunin" from thrush
Candidiasis, or thrush, is a lesion of the mucous membranes of the candida fungus. A colony of fungi can be localized in the oral cavity, in the vagina, on the walls or surfaces of internal organs. The advanced form of candidiasis has the appearance of a white coating, which, when cleansed, leaves blood spots on the mucosa. Vaginal candidiasis can manifest as cheesy discharge.
In the vast majority of cases, vaginal candidiasis is treated with vaginal tablets, not Irunin capsules. This is due to the fact that the effect of the drug begins at the very site of infection. Irunin cannot penetrate the blood from the vaginal mucosa, which means that the internal organs do not suffer from an increased concentration of the drug.
A vaginal tablet is best placed at night. Lying on your back, carefully insert it into the vagina. If menstruation has begun in the middle of the Irunin suppository cycle, then you should go to the capsule. Do not interrupt the course of treatment. There are many positive reviews about the effect of the drug. Irunin from thrush is used both in the form of capsules and in the form of vaginal tablets.
To avoid relapse, both partners should undergo treatment. With thrush, the course can last 1-2 weeks. If necessary, treatment is repeated.
"Irunin" from nail fungus
The treatment of fungus on the nails is a very long process that can take several months. Therapy takes place in several stages. The reception courses of "Irunin" are periodically repeated.
The drug must be taken in a dosage of 100 mg 1 time per day. The first course lasts 14 days. After this, you need to take a break for 3-4 weeks, then the course is repeated.
If the nail fungus has a neglected form, then 100 mg capsules are taken 2 times a day for three months. Such treatment can cause a lot of side effects, so it is necessary to undergo it under the strict supervision of a specialist. Throughout the course, you need to monitor the performance and condition of the liver, passing tests.
To enhance the action of Irunin, you can use local preparations. Ointments or gels must be applied directly to the affected nails.
"Irunin" from lichen
Pityriasis versicolor is a fungal disease that is diagnosed, usually in the summer. The horny part of the epidermis is affected, and spots of various shades appear on the skin.
For the treatment of "Irunin" you need to take 200 mg 1 time per day for 3 days. This is true in the presence of severe depriving. At the initial stages of the development of the disease, local preparations will help: ointments, sprays and solutions.
The best option for combating pityriasis versicolor is an integrated approach to treatment. This option will be most effective, and the likelihood of a relapse will decrease significantly. During this period, it is better to use specialized hair cosmetics. Shampoo should contain ketoconazole. It can also be used as a shower gel. But do not keep this shampoo on your skin for more than 5 minutes.
Side effects
In some cases, there are side effects of Irunin. The cause may be individual intolerance to the components or prolonged use of the drug in the treatment of complex chronic diseases. Side effects of the drug may be as follows:
- nausea, vomiting;
- stomach ache;
- constipation;
- dizziness;
- headache;
- swelling
- heart failure;
- itchy skin;
- hives;
- hair loss.
A medication can cause side effects, as a rule, in case of violation of the regimen of admission, the presence of contraindications or individual intolerance. Carefully read the instructions for use "Irunina" before taking the drug. If you started taking the medicine and felt very sick, you should stop taking the drug and consult a doctor. Perhaps you will find contraindications for taking "Irunin".
Compatibility "Irunina" with other drugs and alcohol
The most pressing issue is the compatibility of Irunin and alcohol. If you are undergoing a long course of treatment, then throughout this time you should completely abandon alcohol. Alcohol not only reduces the effectiveness of Irunin, but also harms the patient's body. Alcohol can enhance the unwanted effects of hepatotoxic drugs.
In relation to other medicines there are no special contraindications. The action of "Irunin" is able to strengthen the drugs "Erythromycin", "Ritonavir." The opposite effect is given by "Rifampicin", "Carbamazepine", "Diphenin". These drugs reduce the effect of Irunin, create obstacles to the breakdown of the active substance.
Finally
Do not wait for the fungus to pass by itself; this will not happen. The more time passes, the more the disease progresses. Proceed with treatment after detecting the first signs. It is better to deal with the disease comprehensively. Before starting the course of treatment with Irunin, be sure to consult a doctor. Only he can determine the presence of risks and give qualified recommendations for taking the drug.