The most common joint pathology, affecting articular cartilage and areas of bones located in the immediate vicinity of it, is called osteoarthritis. The most characteristic symptoms of this disease are pain and a gradual decrease in articular function. These manifestations entail a significant deterioration in the quality of human life.
More recently, the whole range of measures that could be used to alleviate the condition of the patient was to prescribe painkillers and anti-inflammatory drugs by the doctor, which did not have any positive effect on the metabolic processes in cartilage tissues.
Today, the pharmaceutical market is ready to offer its consumers a whole range of chondroprotective drugs. These preparations are natural components of cartilage and are intended for long-term use. One such drug is Chondrosamine. Instructions for use contain detailed information about the medication, its area of influence, properties and the expected effect.
The composition of the drug
Chondroitin sulfate and glucosamine hydrochloride are the main active components of the medication "Chondrosamine."
The first component is contained in a volume of 20 mg, the second - 250 mg. If we are talking about the drug "Chondrosamine NEO", the instruction brings to the attention of consumers about the presence of ibuprofen as a component in a volume of 100 mg.
As additional components that make up the drug, the manufacturer claims the presence of crospovidone, colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose.
Pharmacodynamics
The tandem of the main active components of Chondrosamine is involved in the biosynthesis of connective tissues. The result is the blocking of cartilage destruction processes and the stimulation of cartilage tissue regeneration. As a result, pain sensations become less intense, joint inflammatory processes decrease, and their (joints) mobility increases.
Chondroitin has an effect on the phosphorus-calcium metabolism in cartilage, inhibits the leaching of calcium and inhibits destructive processes, and stimulates bone regeneration. Glucosamine stimulates the synthesis of substances, which are a kind of building material, from which articular membranes, cartilage tissues and intraarticular fluid are subsequently created. Protection against chemical damage, including those caused by prolonged use of NSAIDs and GCS, is also one of the functions of glucosamine, which is part of the drug “Chondrosamine”. Reviews of experts report on its effective anti-inflammatory effect. The systematic use of the drug can slow down the development of degenerative processes leading to negative changes in the joints, spine and soft tissues located next to it.
Thus, Chondrosamine (the instruction confirms this information) makes it possible to significantly reduce the dose of non-steroidal anti-inflammatory drugs taken by patients.
Application area
Usually, “Chondrosamine” instructions for use recommend that patients from 15 years of age are recommended as a component of the complex for the treatment of diseases of the musculoskeletal system. However, this is not the only area of application of this medication. The drug is permissible to use in any condition during which there are changes in the cartilage tissue, which are degenerative-dystrophic in nature.
The “Chondrosamine” instruction allows for use in osteoarthritis and osteoporosis, in case of osteochondrosis and spondylosis, in periodontopathy and shoulder-shoulder periarthritis, in degenerative diseases of the joints and spine and in fractures (to stimulate bone marrow formation ).
Scheme of application and dosage
Chondrosamine tablets are prescribed by the patient for admission to patients from 15 years of age in a dosage of 2 pieces with a frequency of 2-4 times during the day. The drug should be washed down with a small amount of liquid (preferably water).
A month later, from the start of the course of therapy, it is possible to reduce the dosage to 2 tablets or capsules 1-2 times a day. The optimal, minimum effective dose should be selected by the attending physician.
Typically, the course of treatment is from one and a half to three months. A stable positive effect is usually achieved when taking "Chondrosamine" for at least six months.
"Chondrosamine NEO" instructions for use regulates the intake according to the same scheme and in the same doses as "Chondrosamine." Without consulting a doctor, it is unacceptable to take the drug for more than 3 weeks.
Contraindications
As with any medicine, there are contraindications for the use of the medication "Chondrosamine." Instructions, reviews and recommendations of medical specialists prohibit taking this medication for those who have a history of individual hypersensitivity to any of the components of the medication, to acetylsalicylic acid and other NSAIDs.
The reason for refusing to use the patient is phenylketonuria, serious deviations in the functioning of the kidneys, hemophilia (and other deviations in the blood coagulation system, hypocoagulation, including).
"Chondrosamine NEO" is not prescribed for people suffering from any erosive and ulcerative diseases of the gastrointestinal tract, hemorrhagic diathesis, LCD bleeding, intracranial hemorrhage.
Contraindications for the use of "Chondrosamine" are pregnancy, lactation, age up to 15 years.
Excess dose
To date, cases of overdose are not described. If, for some reason, an unacceptably large dose of the Chondrosamine medication is nevertheless taken, the instruction recommends gastric lavage and symptomatic treatment in accordance with the patient’s condition.
Feasible side effects
The development of side effects is possible with an overdose or in the presence of individual hypersensitivity to any of the components of the drug "Chondrosamine". The instruction reports that in such cases, dysfunction of the gastrointestinal tract, allergic reactions to the skin, and dizziness may develop.
As for Chondrosamine NEO, there can be significantly more side effects due to the presence of ibuprofen in the medication. Negative manifestations can occur from different systems of the body (digestive, respiratory, cardiovascular, urinary, hematopoietic and coagulation systems), the development of skin allergic reactions, and a change in laboratory parameters are possible.
If another form of the release of the drug “Chondrosamine” is used - ointment - the instruction informs consumers that skin allergic reactions, itching, and hyperemia can develop as side effects. If such an effect takes place, it is necessary to discontinue treatment and conduct desensitizing therapy.
What to look for?
It is unacceptable to exceed the dose recommended by the doctor and independently increase the duration of the medication. With a parallel intake, the absorption of tetracyclines from the gastrointestinal tract increases, and penicillins and chloramphenicol decrease. The drug is compatible with other NSAIDs, so if you need to take additional non-steroidal anti-inflammatory drugs for a long time, you should give preference to “Chondrosamine” as not containing (unlike “Chondrosamine NEO”) ibuprofen in its composition.
“Chondrosamine” in no way affects the ability to drive vehicles and to perform work that requires increased attention and speed of psychomotor reactions. But patients taking "Chonrosamine NEO" should refrain from these activities.
Patient opinion
Like any medicine, Chondrosamine has both positive and negative feedback from consumers. For most patients, the medication was useful and helped to cope with acute pain. In addition, the drug is affordable. Basically, the same reaction in patients to Chondrosamine NEO. Instructions, reviews of consumers and health workers characterize it as an effective tool.
However, there is such a group of patients who spoke about the drug in a negative way. People began to develop side effects in the gastrointestinal tract, and skin reactions appeared. I must say that they responded to a greater extent about the drug “Chondrosamine NEO”. This is most likely due to the presence of ibuprofen in the composition.
In any case, patients who were satisfied with the results of treatment are much more. And if any negative effects appear, you should consult a doctor to adjust the dose or replace the medication with any other. Fortunately, Chondrosamine has enough analogues.