"Bifidumbacterin" is a drug that contains live bifidobacteria. It is used to treat pathologies that are associated with an imbalance of microbes in the intestinal lumen. The method of application of Bifidumbacterin depends on the age of the person and the state of his digestive tract.
Active substance
The preparation contains bifidobacteria, which are gram-positive bacilli, the necessary condition for the existence of which is the oxygen-free environment of the intestine. They are grown on a nutrient medium and packaged in various dosage forms, on which the method of application of Bifidumbacterin depends.
These bacteria are necessary for the body to carry out protective processes against toxic substances, pathogenic microflora, strengthening immunity and increasing the number of beneficial microorganisms. Enhanced digestion in the intestinal wall is due to bifidobacteria. These sticks are useful for absorption and production of vital substances: vitamin K and D, folic acid, pyridoxine, nicotinic and pantothenic acids, thiamine and riboflavin, as well as proteins, amino acids, iron and calcium.
Pharmacological properties
The drug belongs to probiotics, that is, agents that improve the digestive processes in the human intestines. Once in the body, bifidobacteria begin their therapeutic effect, displacing many types of pathological bacteria that cause inflammation and dyspeptic manifestations. The numerical amount of beneficial microflora begins to outweigh the harmful microbes, therefore, the body gets rid of dysbiosis, improves metabolism, and increases local immunity, since there is a large amount of lymphoid tissue in the intestine. With the oral method of using Bifidumbacterin, it quickly enters the gastrointestinal tract and begins to act. The medicine is not absorbed into the bloodstream, it is excreted in feces.
Indications
Dosage and administration of "Bifidumbacterin" depend on the age of the patient. The drug has no age restrictions and is suitable even for newborns.
The drug is indicated:
- For the treatment of undetermined intestinal pathology in children who are ill for a long time with the main manifestation in the form of dyspeptic symptoms.
- For the prevention of functional disorders of the intestinal tract in children.
- To combat the formation of ulcerative necrotic lesions of the intestine in children of all ages, including premature infants.
- For the treatment of bacterial and viral infections of the intestine, proceeding in acute form. It is prescribed in combination with other drugs, including etiotropic.
- To restore the balance of microflora after intestinal infections.
- To prevent dysbacteriosis in premature infants receiving antibiotic therapy, as well as newborns whose mothers were taking antibiotics, they suffered late toxicosis, infants who had a difficult birth or had been without amniotic fluid for a long time.
- For preventive purposes, the drug is indicated for infants whose mothers suffered from mastitis, lactostasis, and nipple injuries.
- The use of "Bifidumbacterin" for newborns in a manner that will be described below is also necessary to enhance the protective properties of the body with anemia, low body weight, rickets, allergic manifestations, and infections of the respiratory system.
- When transferring babies from mother’s milk to artificial mixtures.
- Adults and children of older age groups with intestinal pathologies caused by infectious agents in the acute stage and with chronic process, as well as with inflammatory processes in the colon and small intestine, accompanied by a shift of microflora in the pathological direction.
- For the treatment and prevention of dysbiosis resulting from prolonged use of antibacterial drugs, as well as in individuals receiving hormone therapy, radiation.
- For preventive and therapeutic purposes in people exposed to stress and extreme conditions, including starvation.
- For the prevention of intestinal problems in pregnant women and women in labor who are in maternity hospitals and departments with an unfavorable situation for the incidence of acute intestinal infections.
- For the treatment of breast nipples in nursing women with a flat nipple, with its cracks and inflammation.
- To improve the microflora of the vagina of pregnant women who have a shift in the pathological direction in the vaginal secretion, that is, purity of the III-IV degree.
- For the treatment of vaginal inflammation, which appeared with an increase in staphylococcus and E. coli in women of childbearing age and pregnant women.
- For the treatment of inflammatory vaginal processes associated with menopausal hormonal disorders in women.
Method of use "Bifidumbacterin" for adults
The drug is prescribed in the form of a powder for the preparation of a suspension taken orally, tablets in different dosages, capsules, suppositories for vaginal and rectal administration with different numbers of colony forming units.
The method of application of "Bifidumbacterin" in ampoules in which the lyophilized powder is located depends on the pathology:
- In intestinal pathological processes - inside orally.
- For therapeutic enemas, enter the intestines with a syringe.
- With gynecological pathologies - intravaginally.
- With mastitis and fissures of the nipples, as well as for their prevention, locally with a cotton swab.
Method of using “Bifidumbacterin” in powder in adults for the prevention of dysbiosis: the drug substance in a glass vial must be diluted with boiled clean water until dissolved. One such ampoule contains five doses of bifidobacteria, which must be taken twice a day. The duration of prophylactic administration depends on the health of the human intestines and can last from two to three weeks. Such courses can be carried out 2-3 times during the year, depending on the situation and the use of other drugs. The method of application of Bifidumbacterin for prophylaxis is oral, half an hour before a meal.
For the treatment of dysbiosis, the drug is taken in 2 ampoules (10 doses) 3-4 times a day (up to six times, depending on the severity of the process).
For the introduction into the vagina of a solution of powder diluted with water, a sterile cotton swab is moistened, which remains inside for about three hours, and then is removed. Repeat the procedure every 12 hours. For this procedure, use two vials at a time. Conduct medical manipulations up to ten days. To facilitate the procedure, "Bifidumbacterin" is released in the form of suppositories, one dose in each suppository.
To treat the mammary gland and nipples, the contents of one bottle are diluted with water and applied with a cotton swab for half an hour before feeding the baby.
Medical enemas with a medicinal substance are made (half an hour after cleansing enemas) by introducing 2-3 bottles of powder dissolved in 40 ml of boiled water, cooled to room temperature. Such manipulations are carried out once a day for ten days. Such enemas can be replaced with the drug in rectal suppositories, which contain one dose (10 CFU) of bifidobacteria.
Instructions and how to use "Bifidumbacterin" in bags in adults is similar to ampoules with powder. Each package contains five doses of the drug, which corresponds to 50 million colony forming units. Contents dissolve in pure boiled water or liquid food. The preventive dose for adults is 2 packets per day. And the method of using “Bifidumbacterin” in sachets for the treatment of acute and chronic intestinal pathology, accompanied by a negative shift in the intestinal microflora, is two pieces for 3-4 daily doses.
"Bifidumbacterin forte" contains 5 doses of the substance and is available in powders and capsules. The use of "Bifidumbacterin forte" in a way that will help eliminate or prevent dysbiosis in adults, possibly orally (capsules and powder), in gynecological practice intravaginally (powder), as well as for the treatment of nipples in obstetrics (powder).
Bifidumbacterin forte capsules are taken in two pieces 3-4 times a day for medicinal purposes and 1-2 capsules 1-2 times a day for the prevention of dysbiosis. The duration of the course can be up to three weeks. For the treatment of chronic intestinal pathology, it is possible to take ten capsules per day once or divided into three doses.
Acute intestinal infections involve large doses - 10 capsules three times a day in short courses for up to three days.
With planned surgical interventions in the intestine, the drug is prescribed two capsules three times a day for five days before the operation and up to two weeks after it.
Method of application of Bifidumbacterin for children
The drug is used from the first days of life, even in premature infants, which suggests a wide range of its use and good tolerance.
The method of application of Bifidumbacterin for newborns depends on the pathology in which it is prescribed by a doctor.
For the treatment of dysbiosis in infants up to six months, the drug is taken in three doses three times a day. The course of treatment lasts up to a month. For prophylaxis, use 1-2 doses three times a day or five doses once a day.
The method of application of Bifidumbacterin for newborns in ampoules is oral. Ampoules are glass vials containing powder with a nutrient medium and bifidobacteria. The contents are taken with breast milk or an artificial mixture.
The method of application of "Bifidumbacterin" for newborns in powder, which is contained in bags, is no different from what is included in the ampoules.
For children over six months of age, the drug is prescribed for treatment and prophylactic purposes in 5 doses twice a day.
With the threat of serious intestinal pathological processes (like ulcerative necrotic inflammation of the intestine), infants are prescribed up to ten doses per day.
Children from the age of three can receive prophylactic dosages the same as adults (10 doses 1-2 times a day).
For therapeutic purposes, children from six months to three years are prescribed five doses of bifidobacteria 3-4 times a day. From three to seven years, you can increase the medication up to five times a day for 5 doses. From the age of seven, adult dosages of 10 doses 3-4 times a day are permissible, and if necessary, the number of doses can be increased to six. Children who are no longer breast-fed by age should take Bifidumbacterin half an hour before a meal.
Candles can be used for children after three years.
Use the drug in capsules should be for children older than three years. One capsule contains 5 doses of the drug. If it is impossible to find a powder form for small children, the capsule is opened, and the powder is diluted from it with water.
Contraindications
"Bifidumbacterin" is taken by adults, including pregnant women, as well as children of all ages, starting from birth.
You can not take the drug with established individual intolerance.
The drug in the form of suppositories is not prescribed for children under the age of three.
Side effects and features of application
The drug is well tolerated. Of the side effects, rare allergic reactions in the form of a skin rash can be noted.
Powders for oral administration, as well as tablets and capsules of "Bifidumbacterin", it is undesirable to mix with antibacterial drugs that are taken orally. For this, it is better to use the dosage form in suppositories.
The drug in powder should not be dissolved in water above 40 degrees and stored as a solution.
It is forbidden to use candles that have an unpleasant bitter smell and a packaging defect.
Caution is advised to take the medication for persons with lactase deficiency, since powders, capsules, and tablets contain a small amount of lactose monohydrate as an auxiliary component.
The shelf life of the drug is one year. It is forbidden to use after the expiration of the term.
Interactions with other medicinal substances
"Bifidumbacterin" practically does not interact with other drugs, as it is not absorbed into the bloodstream, but acts in the intestinal lumen. The exception is vitamin preparations containing group B (thiamine, riboflavin, pyridoxine, pantothenic acid, folic acid, biotin, cyanocobalamin) in combination or alone, can enhance the effect of the probiotic. As well as antibacterial drugs that reduce the effectiveness of treatment with Bifidumbacterin.
Forms of release, analogues and prices
"Bifidumbacterin" in the form of lyophilized powder for oral administration in a dosage of 5 doses in one bottle of 10 pieces per box is produced by domestic companies CJSC Ecopolis, JSC Microgen NPO, CJSC Vitafarma.
“Bifidumbacterin” and “Bifidumbacterin forte” in sachets with powder in five doses in each in packages of 10 and 30 pieces of the company “Partner” of Russian production.
The drug is in tablets of 1 and 5 doses of LLC Ekko Plus and ZAO Vitafarma, manufactured in Russia.
Capsules with bifidobacteria of 5 doses in each domestic manufacturer LLC "Lanafarm" and ZAO "Ecopolis".
Suppositories for vaginal and rectal administration, containing 1 dose of a medicinal substance, are produced by the companies ZAO Vitafarma, FSUE NPO Mikrogen and JSC Partner of the Russian Federation.
The price range for these drugs in pharmacies ranges from 88 to 350 rubles per package, depending on the form of release and the company manufacturing the drug.
Reviews
According to statistics obtained after studying the reviews of patients taking Bifidumbacterin, as well as parents who used this drug to treat children, this drug is positively estimated from various sources from 70 to 88%. In general, this is a good result, which characterizes the drug as an effective tool in the fight against dysbiosis and intestinal problems, as well as gynecological and obstetric pathologies.
In most cases, doctors respond positively to the drug as a time-tested and safe tool with a low price and a variety of forms for use.