Nemozol is an anthelmintic drug with a wide spectrum of action. The medication is successfully used in the treatment of parasitic infestations, relieves helminths at any phase of the development of the disease.
Release form
The active ingredient is albendazole, it slows down the metabolism of parasites, eliminates the membrane and prevents the absorption of glucose by nematodes.
Important!
The effect of the drug increases while taking it with fatty foods or grapefruits (five times).
In the liver tissue, albendazole is converted to albendazole sulfoxide, a microelement with a pronounced antiparasitic effect. The elimination of helminths occurs quickly - during the day, worms are excreted from the body with feces in a live or digested form.
Nemozol is available in the form of:
- capsules (hard);
- chewable tablets;
- suspensions.
Structure
Chewable tablets contain 400 milligrams of active substance. Additional trace elements are:
- propyl parabens;
- sodium lauryl sulfate;
- starch;
- citric acid;
- povidone-30;
- magnesium stearate;
- gelatin;
- aspartame;
- talc;
- peppermint or pineapple flavor.
Conventional tablets are dispensed in pharmacies at a dosage of 200 and 400 milligrams. Additional elements are:
- starch;
- gelatin;
- propylporaben;
- povidone-30;
- talc.
A special blister with one tablet of 400 milligrams or two tablets of 200 milligrams is enclosed in a cardboard box. The suspension is available in bottles of 20 milliliters, the content of the active substance is 400 milligrams.
Five milliliters of suspension contains 100 milligrams of active ingredient. Excipients are:
- glycerol;
- microcrystalline cellulose;
- potassium hydrochloride;
- benzoic acid;
- sorbitol;
- sorbic acid;
- polysorbate-80;
- ice cream flavor or fruit;
- water.
Indications
How to apply "Nemozol"? Reviews of parasitologists indicate that the drug is used to treat mixed-type invasions. The medicine is prescribed for patients infected with various nematodes. The following diseases are treated with the drug:
- ascariasis (infection with roundworms located in the form of larvae on surfaces);
- enterobiosis (helminthiasis, which is triggered by pinworms);
- hookworm (helminth disease caused by roundworms of the hookworm type);
- necatorosis (helminthiasis from the group of nematodes, characterized by dyspeptic symptoms, signs of allergy and the development of hypochromic anemia);
- trichocephalosis (a parasitic disease caused by a parasite from the genus of round helminths - whipworm);
- mixed helminthic infestations (helminthic infestations, in which several varieties of parasites are present inside the body at once);
- toxocariasis (damage to human tissues and organs with larvae of the parasitic toxocara worm);
- echinococcosis of the lungs, peritoneum, liver (helminthiasis with a chronic course, the cause of which is tapeworm);
- neurocysticercosis (a disease of the nervous system caused by infection with the larvae of the parasite pork tapeworm);
- strongyloidosis (invasion by round helminths - intestinal acne, proceeding with allergic and gastrointestinal syndromes);
- opisthorchiasis (a chronic infectious disease affecting the biliary tract, pancreas, lungs);
- giardiasis (protozoal invasion caused by intestinal giardia and proceeding with signs of a functional digestive disorder);
- teniosis (helminthiasis from the group of cestodoses, characterized by damage to the small intestine);
- clonorchosis (chronic helminthiasis, affecting mainly the biliary system and pancreas);
- neurocysticercosis (a parasitic disease of the nervous system caused by larvae of a pork tapeworm).
In surgery, Nemozole is widely used to remove echinococcal cysts.
pharmachologic effect
The drug acts pointwise on the intestinal tract of helminths. This happens due to the main active ingredient. Albendazole reduces the rate of chemical reactions of beta-tubulin, which suppresses the microtubules in the intestines of worms located in the semi-liquid contents of the cell, and also destroys the ability of nematodes to synthesize a universal energy source and expend sugar.
Instruction manual
According to reviews and instructions, "Nemozol" in the form of tablets is prescribed for both adults and children. It is necessary to take the drug during meals, since fatty foods contribute to better absorption of albendazole.
Need to remember!
The medication can not be crushed or chewed, as this leads to a violation of the membrane, which leads to a failure of the absorption of the active substance.
The necessary dosage in tablets is prescribed based on the disease:
- with ascariasis and trichinosis - one tablet per day;
- with toxocariasis - one tablet per day for seven to ten days;
- with teniosis, strongyloidosis - one tablet per day for three days;
- when the body is affected by various types of helminths, two tablets are used per day in the morning and evening for three to five days;
- with giardiasis in children aged (from three to twelve years), the doctor basically prescribes one tablet per day for five days.
Suspension "Nemozol"
Five milliliters of the drug contains 100 milligrams of the active substance. How to apply the suspension:
- With neurocysticercosis and echinococcosis with a body weight of more than sixty kilograms, the dose of Nemozole is 20 milliliters twice a day. If the weight is less, then the daily dosage will be fifteen milliliters, you need to take the medicine in two doses. The duration of therapy for neurocysticercosis is from one to four weeks. The duration of treatment for echinococcosis is one month. Therapy is carried out in three stages with breaks of fourteen days.
- With toxacorosis - a medication must be used twenty milliliters twice a day. With a person weighing less than 60 kilograms, the dosage should not be higher than 10 milligrams per kilogram. The duration of the course is from one to two weeks.
How to take the drug for children?
Helminth infection in children sometimes manifests itself in the form of severe intoxication:
- fever;
- rash;
- general malaise.
The baby becomes restless, sleeps poorly, there may be apathy, migraine, pain in the stomach.
Important!
With helminthic invasions, the human body does not receive the necessary trace elements in the right amount, resulting in problems with mental and physical health.
According to reviews, Nemozol is absolutely safe for children. The maximum daily dosage can be prescribed only by a doctor based on age, weight and general health. For children under two years of age, the medicine is prescribed only for severe helminth infections.
In case of damage to the nematodes of the brain, the daily dosage is fifteen milligrams per kilogram of weight, taken for eight days.
With ethereobiosis, ascariasis, the drug must be taken once (200 milligrams), repeated therapy is repeated three weeks later (in case of pinworm infestation).
With cestodosis - once a day, 200 milligrams for three days.
When treating cysticercosis, children over two years of age are given Nemozol twice a day, 400 milligrams each. The duration of treatment varies from eight to thirty days. With giardiasis, the maximum daily dosage is 400 milligrams per day, or ten to fifteen milligrams per kilogram of weight. The duration of therapy is one week.
"Nemozol" for children
The medicine is available in suspension and is taken once. Children under two years of age are prescribed no more than ten milliliters of the drug, which must include at least 200 milligrams of the active substance. According to reviews, "Nemozol" suspension should be prescribed by a doctor, taking into account the weight of the child. Older children are prescribed twenty milliliters per day.
How to take Nemozol as a prophylaxis?
According to the instructions for use and reviews, "Nemozol" for prevention is recommended to be taken in the form of chewable tablets. To get more positive results, doctors advise taking Nemozol together with Dekaris.
Initially, they take one tablet of Dekaris, then, after a couple of days, they carry out therapy with Nemozol. As a rule, the usual prevention of infection with worms is very simple - compliance with basic hygiene rules:
- wash hands thoroughly, as well as vegetables and fruits;
- do not use running water or from a reservoir;
- swim in proven ponds.
Adverse reactions
As a rule, the drug is well tolerated by patients, but among people with individual intolerance, it can cause some undesirable reactions. According to reviews, this is:
- pain in the stomach;
- nausea;
- dry mouth
- vomiting
- loss of appetite;
- increased activity of hepatic transaminases;
- a decrease in the number of white blood cells in the blood;
- thrombocytopenia (a condition characterized by a decrease in platelet count below 150 · 109 / l, which is accompanied by increased bleeding and problems with stopping bleeding);
- agranulocytosis (a serious blood disease associated with a significant decrease in cells from the group of leukocytes, granulocytes);
- severe headaches;
- meningeal symptoms (headache, which is characterized by high intensity).
Contraindications
According to the instructions and reviews, Nemozol (tablets or another form of the drug) has a number of prohibitions. The drug is contraindicated in conditions such as:
- increased individual intolerance to the components that make up the drug;
- pregnancy;
- the period of breastfeeding;
- children under two years old;
- retinal diseases.
Relative bans include:
- dysfunction of the hematopoietic system;
- impaired liver function;
- severe diseases of internal organs, leading to a weakened body.
Analogs
The medicine "Nemozol" has a number of substitute drugs:
- Sanoxal.
- "Gelmadol."
- Zentel.
- Albenzene.
- "Piperazine."
- Azinox.
- "Pirantel."
- Levamisole.
- Mebendazole
- "Metronidazole".
- Praziquantel.
- "Nifuratel."
- "Fumagillin."
“Sanoxal” is an Indian manufacturer’s medicine, dispensed in the form of chewable tablets (400 milligrams of active substance). There is one tablet in the package, the cost of the drug is two hundred rubles.
Gelmadol-VM is an Egyptian-made medication, available in tablet form (200 milligrams of active ingredient). There are two tablets in the package, the cost of the drug is two hundred rubles.
"Zentel" is a British-made drug, dispensed in the form of a suspension, a bottle of 10 milliliters with an active substance content of 400 milligrams. The drug is practically not found in Russia.
“Albenzene” is a medicine of an Indian pharmaceutical company, produced in the form of 400 milligrams of chewable tablets. The average cost (three tablets) is one hundred seventy rubles.
Substitutes with other active substances
According to the instructions and reviews, analogues and Nemozol have a similar spectrum of actions. The following is a list of drugs that have different active trace elements:
"Mebendazole" - the drug is also sold under the trademarks "Vermox" and "Agelmin." The medicine has earned a lot of positive reviews for its high effectiveness, minimal toxicity and versatility. Mebendazole is ineffective for giardiasis, opisthorchiasis and cysticercosis. The price of the drug is ninety-five rubles.
"Lavamizole" - is also produced under the trademarks "Dekaris", "Levamisole-Health". Reviews about the drug are not very encouraging, many patients talk about the high toxicity of the drug, which confirms the ban on its sale in Europe and the United States of America. It is used in the treatment of enterobiasis, ascariasis, necatorosis, toxoplasmosis. The price of the drug varies from 80 to 95 rubles.
Piperazine is the domestic and safest analogue of Nemozol among all synthetic substitutes. This drug can be treated even for children under two years of age. The average cost of the drug (ten tablets) is twenty rubles. The range of action of "piperazine" is somewhat limited, it is effective in combating the following parasites:
"Fumagillin" - is used in the treatment of nosematosis in bees, it is also used in the treatment of eye microsporidiosis in humans.
"Pyrantel" is a drug that has low toxicity, therefore it is suitable even for children. Pirantel copes well with five major infections:
- enterobiosis;
- ascariasis;
- trichocephalosis;
- necatorosis;
- hookworm.
When taking generic group drugs, self-medication is prohibited. If the doctor prescribes Sanoxal or Nemozol, but they are not in the pharmacy, it is better to discuss the possibility of their replacement with an infectious disease specialist.