The drug "Cyclodol" - what is prescribed by doctors? You will find the answer to this question in this article. In addition, we will tell you about how such a medication affects the human body, what contraindications and side effects it has, as well as present to your attention instructions for use and consumer reviews.
Cyclodol - what kind of drug?
The presented drug is classified as central N-anticholinergic. In addition, this medication is included in the group of anticholinergics.
Release form and composition of the drug
According to the instructions attached to the medication, the drug "Cyclodol" goes on sale only in the form of rounded white tablets with a flat surface. The active substance of this agent is trihexyphenidyl hydrochloride. Its amount in one tablet can be 0.001, 0.002 or 0.005 g. One cardboard package contains 2 blisters of 25 tablets.
pharmachologic effect
It should be especially noted that there are both positive and negative consumer reviews about such a medicine. "Cyclodolum" is actively used in parkinsonism. This fact is due to the fact that the presented agent is capable of exerting anticholinergic, central myelorelaxative and peripheral effects.
So what are the reviews about this drug? “Cyclodol” is a medicine that significantly helps to reduce tremor, and also has a weak effect on rigidity and bradykinesia. Due to the fact that this medication has an M-anticholinergic effect on the peripheral nervous system, its use for medicinal purposes contributes to a significant reduction in salivation and sweating.
Pharmacokinetics
One cannot ignore the fact that the Cyclodol drug, the price of which is presented a little further, has the effect of a local anesthetic.
It should also be noted that after taking the total duration of the therapeutic effect on the human body is about 6-12 hours. As for the maximum effect, it lasts about 2-3 hours.
After oral administration (oral), Cyclodol® begins its active action after about 60 minutes.
Indications for use
Why is Cyclodolum prescribed? Analogues of this drug and the named medication itself effectively affect the human body with the following deviations of the nervous system.
- Any disorders of the extrapyramidal system, accompanied by an increased tone of muscle tissue, as well as the presence of hyperkinesis (that is, violent movements that are automatic in nature, which are caused by involuntary muscle contraction).
- Parkinsonism of various etiologies.
It should be especially noted that in order to avoid side effects, such a drug is recommended to be taken only as prescribed by the attending physician and under his direct supervision.
Contraindications
According to experts, the drug Cyclodolum, as well as all its analogues, are potent medicines. In this regard, their use is not recommended for use in some cases.
Thus, taking this drug is highly undesirable if:
- the patient is diagnosed with atrial fibrillation;
- the patient has an increased sensitivity to the main substances of the drug, in particular to trihexyphenidyl;
- the patient revealed diseases of the digestive tract, which are obstructive;
- the patient is diagnosed with an adenoma with the presence of residual urine (or the so-called prostatic hypertrophy);
- the patient suffers from urinary retention;
- patient's age is less than 5 years;
- the woman is pregnant.
In these cases, the Cyclodol medication is recommended to be replaced with other drugs with a completely different active component.
Detailed instructions for use
The instructions attached to this drug say that taking the Cyclodol medication should begin with the minimum permitted doses. In the future, they can gradually increase. However, this should be done only in case of emergency and exclusively under the supervision of the attending doctor.
So in what dosages should Cyclodol be used? The use of this drug depends on the type of diagnosed disease:
- Parkinson's Syndrome. In this pathological condition, it is necessary to start taking the named medication with 1 mg of the active substance per day (that is, trihexyphenidyl hydrochloride). If absolutely necessary, the dosage is increased to 3 mg every 2-4 days. In this case, you should focus on the well-being and condition of the patient. As for the maintenance dose, then with Parkinson's syndrome, it should be about 16 mg per day (maximum). The lower limit of this intake is 6 mg. Distribute the specified amount of the drug, preferably 3-5 times. By the way, taking this drug in doses that exceed 20 mg per day is highly not recommended.
- Extrapyramidal disorders. In this condition, the medication is prescribed up to 16 mg per day (at least 2 mg). The dose for the patient is selected depending on how severe the symptoms of the disease are. The maximum permitted dosage is 20 mg.
- Anticholinergic therapy. With this treatment, the dose of Cyclodol is continuously adjustable. Daily it rises by 2 mg. In this case, the maximum daily dose should be no more than 50 mg.
- Treatment for adolescents and children aged 5-16 years. In such cases, Cyclodolum is prescribed only for therapy during extrapyramidal dystonia. In this case, the maximum daily dosage should not be more than 40 mg.
General recommendations for the use of the drug
Now you know why this medication is indicated, and what reviews are available about it. "Cyclodolum" should be prescribed only by a doctor. Indeed, when applying, you should definitely know about its features.
Such tablets can be used both before and after a meal with a glass of plain water. If before the start of therapy the patient had hypersalivation (or the so-called increased salivation), then this medication is better to take after eating. If during treatment the patient complains of dry mouth, then the Cyclodol medication is preferably used before meals. It should also be noted that this drug is not abolished abruptly. After all, such therapy requires gradual completion. In this case, the dosage is preferably gradually reduced for 1-2 weeks. If you neglect these recommendations, then exacerbation of signs of the underlying disease may occur. By the way, the duration of treatment with the presented drug is determined only by the doctor in each individual case.
The drug "Cyclodol": side effects
According to medical data, the medication presented is able to affect all systems of the human body, causing it to cause unwanted reactions. If the patient has the symptoms described below, it is recommended to seek the advice of a doctor:
- Headaches, disturbance of accommodation, nausea, drowsiness, irritability, vomiting. In addition, signs of increased anxiety, impaired consciousness, memory and sleep may occur. Quite rarely, dyskinesia occurs (that is, involuntary movements).
- Dry mouth, constipation, impaired urination, decreased sweating and tachycardia. Mydriasis, visual impairment, or bradycardia are also very rare.
- Allergic rashes on the skin.
Usually, all of the listed side effects go away on their own or are eliminated by reducing dosages or reducing the frequency of administration.
The price of the drug and its analogues
How much does Cyclodolum cost? The price of this medication in different pharmacy chains can vary between 60-80 Russian rubles and depends on the pharmacological company that produces this medicine. It should also be noted that the presented drug has a large number of analogues that have similar properties. As a rule, they are prescribed if, for some reason, Cyclodolum did not fit the patient’s body.
Analogs of the medication:
- "Tremin."
- "Parkopan."
- Parkinsan.
- "Antitrem".
- "Patitan."
- "Benzhexol hydrochloride."
- "Trixil" and so on.
In order to avoid side effects and worsen the patient’s well-being, these drugs should be used only after consulting a doctor.