For the treatment of various neurological diseases, doctors often prescribe Combilipen. This is a modern drug that has several forms of release. Below are described the situations in which "Combilipen" is prescribed, instructions for use, analogues, side effects and patient reviews.
Indications
The active substances of the drug act on the cells of the body in a specific way. As natural aging occurs, a large number of people experience disturbances in the functioning of the nervous system. As a rule, these are pathologies associated with the development of diseases of the musculoskeletal or diabetes mellitus. Judging by the instructions, “Combilipen” is able to cope with various disorders in the functioning of the nervous system that developed against the background of the course of the above ailments.
The drug is prescribed as a medication in complex treatment. The instructions to “Combilipene” indicate that it has the following positive effect on the body:
- Relieves pain.
- Reduces severity or completely eliminates neurological symptoms.
- Helps normalize the process of hematopoiesis.
- Restores the nervous system.
- Strengthens the body's defenses.
- Helps normalize carbohydrate metabolism.
- Accelerates the production of substances that are directly involved in the conduct of nerve impulses.
- Improves myocardial function, supporting its contractile function.
- Helps to increase the tone of smooth muscles.
- Reduces the level of "bad" cholesterol in the blood.
- Increases the resistance of cells and body tissues to hypoxia.
- Normalizes blood pressure.
According to the instructions, "Combilipen" is effective against the following diseases:
- Neuralgia (both intercostal and trigeminal nerves).
- Osteochondrosis.
- Facial neuritis.
- Arthrosis
- Syndromes resulting from infringement of the vertebral nerves (cervical, scapular, lumbar, lumbago).
- Paralysis.
- Neuropathy.
- Muscle cramps.
- Tinea versicolor.
To enhance the effectiveness of the drug, drugs belonging to the group of muscle relaxants are often prescribed.
Structure
Based on the information specified in the instructions, "Combilipen" is a multivitamin medication. Its composition is represented by three active components:
- Thiamine. Its other name is vitamin B1. As part of the drug, it has a fat-soluble form. A feature of thiamine is that it has the greatest effect on the functioning of the nervous system. With its deficiency, a disease called beriberi can develop. Once in the human body, thiamine improves the conductivity of impulses to nerve cells. He also controls the process of delivering glucose to them.
- Pyridoxine. Its other name is vitamin B6. Pyridoxine is directly involved in most metabolic processes in the body. In particular, it normalizes the cycle of fats, proteins and carbohydrates. Without pyridoxine, it is impossible to create new cells of liquid connective tissue. Also, in the absence of vitamin B6 in the nerve fibers, synaptic signals cease to be transmitted. Pyridoxine and thiamine are components that enhance the action of each other while taking them.
- Cyanocobalamin. Better known as Vitamin B12. Cyanocobalamin plays a major role in the synthesis of substances whose task is to ensure the normal functioning of the peripheral and central nervous system. Vitamin B12 deficiency also leads to anemia.
One of the forms of release of the drug are injections intended for intramuscular injections. The instructions for use with Combilipene indicate that lidocaine is an additional component in them. It is necessary to obtain an anesthetic effect during injection. In addition, lidocaine has a vasodilating effect, due to which the B vitamins entering the body are absorbed better.
Release Forms
Currently, the drug is sold in the form of:
- Injection. According to the information specified in the instructions for use, injections "Combibipen" should be administered intramuscularly. The solution has a specific odor. It is transparent, pinkish red in color. The solution is poured into ampoules of 2 ml. The latter are placed in packs of cardboard. The secondary packaging can be 5 or 10 ampoules. In each of them, 100 mg of thiamine and pyridoxine, as well as 1 mg of cyanocobalamin.
- Pills. On the pharmaceutical market, they are sold under the trade name “Combilipen Tabs”. The instructions indicate that the pills are intended for oral use only. Each tablet is placed in an individual blister cell (in one of them 15 pcs.). Then the packages are put in packs of cardboard of 2 or 4 pcs. The composition of the tablets is also represented by thiamine and pyridoxine (100 mg each), as well as cyanocobalamin (2 μg).
The appropriateness of the appointment of a particular form of release is evaluated only by the attending physician.
Instructions for use
“Combilipen” (both injections and tablets) is a serious drug, despite the fact that it is a vitamin remedy. It is unacceptable to take pills or inject as part of self-medication.
In some cases, the most effective are the intramuscular injections of Combilipene. The instructions indicate that they are usually prescribed for episodes of exacerbations of diseases of a neurological nature. If the doctor recommended injections to the patient, he should also calculate the duration of the course and the regimen.
Unless the specialist has indicated otherwise, it is necessary to use the attached instructions for use for Kombilipena injections. A single dosage of the solution is 2 ml. According to the instructions, Kombilipen injections must be done daily for a week if the symptoms of the disease are pronounced. In the future, within 14 days, you need to enter 4-6 injections. If the pathology has a mild severity, it is enough to do 2-3 injections per week. The duration of the course is 5-7 days.
According to the information specified in the instructions for use for injections of "Combilipene", the patient can enter the drug intramuscularly on his own. To do this, follow a certain algorithm:
- Choose the most comfortable position. It is allowed to inject into the femoral or gluteal muscle. The latter is considered the most developed. In addition, the manufacturer also recommends that “Combiben” be administered intramuscularly in the buttock muscle in the instructions for use. This is due to the fact that it is difficult to correctly inject yourself in the area of the femoral muscle. In addition, the introduction of an injection into this area by a person without a medical education increases the risk of various negative consequences.
- Determine the desired zone. The injection must be introduced into the upper outer quadrant of the muscle. In order to determine the desired area, it is recommended to visually divide the buttock into 4 parts. The upper outer zone is the same quadrant. In order to control the process of drug administration, it is recommended to sit at the mirror standing or lying on its side.
- Open the ampoule and fill the syringe with a solution. According to the instructions, intramuscularly “Combilipen” is administered in an amount of 2 ml. Then you need to vertically place the syringe and squeeze air out of it. As soon as the solution flows out of the needle, the medical device can be put off. Immediately before the injection, wipe the desired quadrant with an alcohol cloth.
- Having taken the chosen position, take the syringe in your hand and insert the needle with a sharp movement. It should enter the muscle to a depth of 3/4, if fully - do not be afraid. Slowly press the plunger until the medicine in the syringe runs out. With a sharp movement, pull out the needle, apply a clean alcohol napkin to the injection site. Then it is recommended to massage the injection site.
Based on the information specified in the instructions for use, Kombilipen injections are extremely effective. This is due to the fact that the active substances remain at the injection site for a long time, getting into the bloodstream gradually.
According to the instructions, “Combilipen Tabs” is prescribed if the disease has passed into a chronic form, or if the pathology is outside the stage of exacerbation. The duration of the course of treatment is determined by the doctor individually, it is calculated on the basis of the severity of the disease and the patient’s health characteristics. In most cases, it is enough to take the drug for a month. The instructions for use with Combilipen tablets indicate that with a treatment duration of more than 6 months, the risk of developing neuropathies is significantly increased.
The frequency of taking the drug is also determined by the doctor in each case. Judging by the information specified in the instructions, Kombilipen tablets are allowed to be used up to 3 times a day. The standard dosage is 1 pill. The instructions for Kombilipen tablets also indicate that the remedy must be taken after a meal. In this case, it is recommended to drink pills with a small amount of water.
Contraindications
According to the instructions for use, Kombilipen injections and the tablet form of the drug are not prescribed for women during the period of gestation and during lactation. This is due to the fact that the active components of the drug have the ability to penetrate into breast milk and through the placental barrier to the fetus.
Also, judging by the instructions for use, Combilipen Tabs tablets and the injection form of the drug are contraindicated for the treatment of children. At present, there is not enough information indicating the safety of receiving funds from this category of people. In addition, the medication is not recommended for children due to the presence of an auxiliary component in it - benzyl alcohol, albeit in a small amount.
According to the instructions, Kombilipen injections and tablets are also contraindicated in the presence of acute heart failure. In addition, the drug is not prescribed in the presence of individual intolerance to the components that make up its composition.
Side effects
In some cases, against the background of reception, deterioration of health is noted. According to the information specified in the instructions for use with Combilipen tablets, the following side effects may appear during treatment:
- rashes on the skin;
- blackheads on the face;
- hives;
- a feeling of heaviness in the stomach;
- dyspepsia;
- nausea;
- sharp jumps in blood pressure;
- headaches;
- tachycardia;
- swelling of the extremities.
It was noted that the use of an injectable form less often causes a deterioration in well-being. In rare cases, a skin rash and systemic reactions appear.
When taking the drug in an amount significantly higher than the standard recommended, an overdose occurs. This condition is characterized by increased severity of side effects. In case of an overdose, symptomatic therapy is prescribed.
Drug interaction
If at the time of prescribing Combibipen, the patient is taking any other medications, you should inform your doctor about this. This need is due to the fact that some substances significantly reduce the effectiveness of the active components of the drug up to the complete neutralization of their action.
“Combilipen” is not recommended for use with funds that include:
- tannic or riboflavic acid;
- dextrose;
- copper;
- ascorbic acid;
- salts of heavy metals.
The drug in the form of a solution contains lidocaine. If you use it with drugs that contain epinephrine, you can significantly disrupt the functioning of the cardiovascular system.
Due to the risk of overdose, the drug is not recommended to be taken simultaneously with other multivitamins. It is also important to consider that the product is incompatible with any alcohol-containing drinks. This is because alcohol reduces the effectiveness of treatment to zero.
Analogs
“Kombilipen” is a drug whose active substances are some of the vitamins of group B. Currently, there are only a few types of drugs on the pharmaceutical market that are structural analogues of the drug.
These include:
- The Milgamma. Available in the form of tablets and injection. Instructions of the analogue and “Combibipen” are as identical as possible. Thiamine, pyridoxine and cyanocobalamin are also active components. The drug has a wider list of side effects. These include: allergic reactions, impaired consciousness, dizziness, arrhythmia, tachycardia, vomiting, acne, itching, increased sweating, urticaria, muscle cramps, irritation in the injection area.
- "Vitagamma." The composition of the drug is identical to Combilipene, the difference is in the dosage of the active components. The drug is also prescribed for the treatment of diseases of a neurological nature and as an adjuvant in the complex therapy of such pathologies.
- "Trigamma." It is prescribed in the complex treatment of neurological ailments. The composition of the drug is also identical to Combilipene. The remedy has more side effects, among which are: anaphylactic shock, angioedema, and shortness of breath. The treatment regimen is also identical.
- "Unigamma." A drug characterized by a pronounced therapeutic effect. Like all analogues, the drug is not prescribed for children under the age of 18 years; pregnant and lactating women; persons suffering from heart failure.
If for any reason the patient wishes to replace Combilipen with an analogue, you must first consult your doctor. This is due to the fact that each drug contains different dosages of the active components, which can negatively affect the state of health.
Reviews
According to the instructions for use, injections of Combilipene intramuscularly are extremely rarely accompanied by a deterioration in well-being. The risk of side effects is slightly higher in the tablet form. Nevertheless, numerous reviews confirm that Combilipen is well tolerated in most cases. Rare cases of deterioration of well-being are associated, as a rule, with an improperly selected dosage or non-compliance with the algorithm for injecting a solution.
Finally
“Combilipen” is a modern drug intended for the treatment of pathologies of a neurological nature. The tool is available in two forms: tablet and as a solution for injection. The feasibility of their appointment is determined by the doctor in each case. The drug is not prescribed for children, lactating and pregnant women, as well as people with heart failure.