In the article, we consider what the Omnic tablets are from. It is a medication that is effectively used to treat urination disorders that accompany benign prostatic hyperplasia. You can buy the drug only by prescription. It retains its therapeutic properties for 4 years if the storage conditions described in the manufacturer's annotation are observed.
Structure
According to the instructions for Omnic tablets, the main active ingredient in the composition is tamsulosin. Each capsule contains 400 mcg.
The auxiliary components are: red, yellow iron oxide, titanium dioxide, gelatin, indigodyne, talc, calcium stearate, polysorbate 80, methacrylic acid copolymer, triacetin, microcrystalline cellulose, sodium lauryl sulfate.
Pharmacological forms
Omnik prostatitis tablets are produced by the manufacturer in a single pharmacological form - capsules, which are characterized by a modified release. One package may contain 100, 30, 10 capsules. According to its pharmacological group, the drug refers to alpha-adrenolytic drugs.
Pharmacokinetics, pharmacodynamics
Tamsuzolin in its drug group is a specific blocker of postsynaptic alpha1-adrenergic receptors that are present in the smooth muscle structures of the prostate gland, in the prostatic urethra in men, in the neck of the bladder. As a result of tamsulosin blocking of these receptors, the muscle tone of the prostate, bladder, and prostatic urethra is reduced. As a result, urination improves. Along with this, there is a weakening of the symptoms of fullness of the bladder and emptying with prostate adenoma, which is due to hyperactivity of the detrusor, as well as increased muscle tone of these organs.
Tamsulosin acts on alpha-adrenergic receptors of type 1A 20 times more strongly than on alpha-adrenergic receptors of type 1B, which are located in the smooth muscle structures of blood vessels. Such a high selectivity of the substance avoids a clinically significant decrease in systemic blood pressure not only in patients with normal blood pressure, but also in patients who suffer from hypertension. That is, Omnic can be used to treat hypertensive patients.
Tamsulosin is well absorbed in the intestine, and its bioavailability reaches 100%. The adsorption process slows down a bit if you combine the drug with food intake. The degree of absorption will be equivalent if the patient constantly takes the medicine after tomorrow.
A feature of tamsulosin is that it has linear kinetics. A single oral administration of 0.4 mg of the substance leads to a maximum concentration in the blood after 6 hours, and a constant daily oral administration of 0.4 mg of the substance on the 5th day leads to the appearance of an equilibrium concentration. Tamsulosin binds to plasma proteins by 99%.
The active substance is metabolized in the liver tissues very slowly, as a result of which less active metabolites are released. Most of the substance taken is concentrated in the blood, and in an unchanged form.
Clinical studies prove that tamsulosin is able to slightly induce the activity of microsomal liver enzymes. In case of weak and moderate pathological changes in this organ, dose adjustment of Omnic is not required.
The unchanged active substance of the drug, as well as its metabolites, are eliminated by the kidneys, and the half-elimination period of a single dose of 0.4 mg is 10 hours. If the application is carried out repeatedly, then this period is up to 13 hours.
With moderate pathological changes in the kidneys, adjustment of the dosage regimen is also not required, however, with severe forms of renal failure, caution is advised when using the drug.
So, what are Omnic tablets from?
Indications for use
The main indication for the use of this medication is the treatment of dysuric disorders that accompany prostate adenoma.
Omnic tablets are also used to prevent prostatitis and neoplasms in the tissues of the gland. From what they help best, the doctor will tell.
The drug created by the Netherlands pharmaceutical company immediately became popular among urologists. The experience in the treatment of prostatitis and prostate adenoma was excellent. Now it is recognized by many as the best medicine for use in men suffering from impaired urination due to prostatitis, with prostatic hyperplasia. From what Omnic tablets are prescribed, it is important to find out in advance.
Contraindications
According to the instructions for use, Omnic tablets are contraindicated for use in the following cases:
- Orthostatic hypotension, in other words, a drop in blood pressure with a change in body position, or a history of data about it.
- Severe forms of liver failure.
- The individual hypersensitivity of the patient to tamsulosin or any other component in the composition of the medicinal product.
It is important to exercise caution when prescribing the drug to patients who are diagnosed with severe forms of pathological changes in the kidneys.
Negative impact
As the instruction for Omnic tablets indicates, against the background of its use in patients, the following negative symptoms are occasionally noted:
- Hypersensitivity phenomena (angioedema, itching, rash).
- Diarrhea.
- Headache.
- Palpitations, tachycardia.
- Constipation.
- Asthenia.
- Vomiting, nausea.
- The development of orthostatic hypotension.
- Dizziness.
- Retrograde ejaculation.
If this negative symptomatology occurs, it is recommended to consult a specialist.
Using Omnic
Capsules of the drug are intended for oral use. It is recommended to take the drug at the end of breakfast, while drinking with water in an amount of 150 ml. The daily dosage is 1 capsule, which is 400 micrograms of tamsulosin. In accordance with the manufacturer's annotation, chewing of capsules is unacceptable - this will lead to the fact that the active component begins to be released at a high speed.
Overdose
According to the instructions and reviews for Omnik tablets, no cases of acute overdose of tamsulosin developed. However, the use of excessive doses of this medication can lead to a rapid decrease in blood pressure, the development of compensatory tachycardia, which requires symptomatic therapy. The hell and heart rate of the patient may return to normal when he takes a horizontal position. If this method is ineffective, the patient is prescribed drugs that increase the amount of blood that circulates in the vascular bed.
If necessary, medications that narrow the blood vessels can be prescribed. In the process of taking Omnic tablets, renal function should be monitored. Due to the fact that the active component of the drug significantly binds to plasma proteins, the effectiveness of hemodialysis is in doubt. In addition, the use of sorbents and the cleaning of the gastrointestinal tract (rinsing, the use of laxatives) are appropriate.
Interaction with other medicines
The combination of tamsulosin with enalaprim, nifedipine, atenolol does not lead to any interactions of substances.
Parallel administration of Omnik and cimetidine can cause an increase in the concentration of tamsulosin in the blood plasma, while combination with furosemide leads to a decrease in its concentration. At the same time, adjusting the dosage regimen when combining these medications is not required, since the concentration of tamsulosin in the blood remains within normal limits.
Glibenclamide, simvastatin, diclofenac, chlormadinone, amitriptyline, trichloromethiazide, diazepam, propranolol, warfarin do not affect the free tamsulosin fraction in the blood. In turn, tamsulosin does not violate the free fractions of trichloromethiazide, diazepam, propranolol, and chlormadinone.
In addition, no interactions of tamsulosin with finasteride, salbutamol, glibenclamide, amitriptyline were noted.
With simultaneous use with diclofenac and warfarin, there is a possibility of an increase in the rate of excretion of the active component.
Combined therapy with other alpha-adrenergic receptor-1 antagonists can lead to a decrease in blood pressure. How to take Omnic tablets, it is better to find out in advance.
Special instructions for use
In some cases, during therapy, a decrease in blood pressure is observed, which can cause a fainting condition. When identifying the primary symptoms of orthostatic hypotension (dizziness, weakness), the patient is recommended to take a horizontal or sitting position and remain in it until the negative effects disappear.
Surgical treatment of the eyes with the goal of cataract therapy using tamsulosin can cause the development of intraoperative instability of the iris. This should be considered by medical personnel in order to properly prepare the patient for surgery.
In accordance with the instructions for use with Omnik tablets, before starting therapy, the patient must be examined to completely exclude pathologies whose symptoms are identical to those of prostate adenoma.
Prior to the start of therapy with a medicinal product, as well as throughout its duration, it is important for the patient to undergo a digital rectal examination, if necessary, determine the presence of specific prostatic antigens.
Analogues of Omnic tablets
If necessary, the medication can be replaced by one of its synonyms or analogues. The most popular are: Vesomni, Urorek, Avodart, Setegis, Alfater, Kornam, Alfirum, Dalfusin, Alfuzosin, Dalfaz, Sonirid Duo, Terazosin "," Sonizin ".
The cost of drugs similar to Omnik varies in a rather wide range and depends on many factors (manufacturer, number of capsules or tablets in the package, active substance, its mass fraction in the drug). For example, a Urorek package containing 30 tablets will cost about 750 rubles, while a Dalphase package with the same number of pills will cost 2.2 thousand rubles.
Omnik and Avodart
These drugs are analogues of each other in their pharmacological group, however, they contain various active substances that affect the pathological processes that are inherent in adenoma. The Omnic medicine is more a symptomatic drug that is designed to eliminate dysuric disorders (it can normalize the process of urination) by relaxing smooth muscle structures in the prostate. The drug βAvodartβ, on the contrary, is designed to reduce the size of the tumor itself by reducing the concentration of dihydrotestosterone, which causes its growth. Both drugs are often used in combination therapy, where their effects complement each other.
The most popular synonyms for Omnik are: Tamzelin, Urofrin, Taniz-K, Focusin, Bazetam, Tamsulon-FS, Sonizin, Omniprost, Tamsulozin, Revokarin β,β Alfatam β,β Omsulosin β,β Proflosin β,β Omnik Okas β,β Adenorm β.
Omnic Ocas and Omnic
On sale you can find the drug "Omnic Okas", 30 tablets per pack. They are 100% percent synonymous, that is, they contain the same active ingredient (tamsulosin) in an identical concentration (400 ΞΌg). It is not surprising that patients suffering from prostate adenoma are often interested in what the difference between these drugs is. Medicines differ in their dosage form: Omnic is available in capsule form, and Omnic Okas is in tablet form.
Moreover, the tablets of the latter are characterized by a controlled release of tamsulosin. That is, they are characterized by a constant concentration of the active component, observed during the day in the body. A similar amount of the drug allows the active substance to equally affect the muscle tissue of the prostate for a whole day. In addition, the absence of differences in tamsulosin concentration reduces the likelihood of developing side effects. However, the instructions for the Omnic Okas tablets should be strictly observed.
"Focusin" and "Omnic"
"Omnic" and "Focusin" are complete synonyms for each other in the active substance and its mass fraction, as well as in pharmacological form. The manufacturers of both medicines are approximately equally popular among patients and doctors, that is, the drugs are completely interchangeable. If there is a need to choose between these two agents, then one should proceed from their cost (Focusin is about a third cheaper than Omnik) and their availability in drugstores.
It is important to remember that all of the listed analogues of the drug have their own list of contraindications, and are also able to provoke the development of specific side symptoms. That is why any replacement of a drug with an analogue is important to coordinate with a specialist.
Use in the treatment of children, in the lactation period, during pregnancy
Due to the fact that prostate adenoma is formed, as a rule, in adulthood, the use of Omnik for the treatment of pediatric patients is not practiced.
The drug is intended for the treatment of men exclusively.
Cost
On average, the cost of an Omnik package, containing 10 capsules, will cost 350 rubles, and having 30 will cost about 750 rubles. 100 capsules "Omnik" costs about 2.5 thousand rubles.
The cost of a medicine may vary depending on the region of distribution, as well as the pricing policy of the pharmacy chain.
Reviews
In about 70% of cases, reviews about Omnic tablets are positive. Urologists often recommend the use of a medication for prostate adenoma, prostatitis, and other pathological changes accompanied by impaired urination, when the relaxing effect of tamsulosin on the smooth muscle structures of the prostate really eliminates the negative manifestations of pathology.
To be fair, it should be noted that there are negative reviews about Omnic Okas tablets associated with the occurrence of side-effects on the background of their use. The most significant of these is the development of retrograde ejaculation and hypotension. In addition, one should not forget that the appointment of the drug in the treatment of prostate adenoma is symptomatic, and is aimed at eliminating dysuric disorders, and the full-fledged therapy of this pathology requires the use of drugs of various groups and an integrated approach.
Among the negative characteristics of the drug, its relatively high cost is also noted. Patients and doctors note that it has a number of analogues and synonyms, the cost of which is significantly lower, and the effectiveness is at the same level.
We examined why Omnic tablets are prescribed.