Energy metabolism is the most important component of the functioning of living cells, because without this substrate no chemical reaction can take place, which means that the tissues will not receive nutrition, the heart will stop, and the brain will die from starvation. That is why the most important source of energy in our cells, the tricarboxylic acid cycle (aka “citrate cycle” or “Krebs cycle”), is activated every microsecond of the present, and in medicine the metabolic drug “Riboxin” has appeared. What is it prescribed for and what is its mechanism of action, we will understand further.
Energy value
And for the implementation of energy metabolism, a constant circulation of substances is necessary , because the person receives substrates for reactions with respiration (primarily oxygen) and nutrition (all organic and inorganic compounds). And therefore, changes in these important revolutions affect the state of our body, and vice versa. So, this happens in severe diseases that lead to damage to internal organs, especially the heart and liver. And therefore, in addition to the therapy of the main pathology, preparations are needed to improve the metabolism in the cells, one of which is the Riboxin. What is he appointed for? To improve metabolism, since its active substance, inosine, is the precursor of ATP (adenosine triphosphate), almost the only energy molecule in our body.
Heart Indications
The first-line organs responsible for metabolism are the heart and liver. The first one is because the speed of the blood circulation in our body depends on the level of its work, and as a result, its saturation with oxygen in the lungs, filling with nutrients in the small intestine, neutralization of toxins in the second most important organ in the metabolism - the liver. And if the heart has undergone dystrophic changes, then an improvement in its work is required due to the Riboxin preparation. What it depends on, we will understand further. Firstly, the myocardium (muscle membrane of the heart) from its three layers is much more likely and easier to suffer from external influences, since it works tirelessly every second of our lives. And therefore, his dystrophy occurs after frequent heavy physical exertion, severe infectious diseases, he undergoes heart attacks, myocarditis, changes due to lung pathology (the so-called "pulmonary heart"). Therefore, it is necessary to treat the underlying disease and reinforce the effect with the Riboxin preparation, for which it is prescribed if the patient has congenital or acquired heart defects.
Other indications
In addition, pronounced metabolic disorders in our body also occur with endocrine pathologies, diseases of the liver, kidneys and gastrointestinal tract. Some of them are also indications for the use of the drug "Riboxin". Why is he prescribed in this case? The indications remain unchanged - the restoration of metabolism, which is impaired by cirrhosis of the liver, its alcohol or drug damage, as well as fatty degeneration, in addition, with peptic ulcer of the stomach and duodenal ulcer, urocroporphyria, poisoning by medical means, chronic alcoholism, the effects of radiation and operations, associated with temporary isolation of the organ from general circulation. As a rule, the Riboxin drug is administered intravenously, but there are other forms of it - capsules and tablets (more for outpatient use).
Pharmacological properties
The main effects of this drug are antihypoxic, antiarrhythmic and metabolic. Due to this, it significantly improves the own blood circulation of the heart (in the coronary arteries), as a result of which the myocardium becomes more resistant to stress, increases its relaxation in diastole and the number of contractions. In case of hypoxia or ATP deficiency, when the body experiences oxygen and energy starvation, the Riboxin drug is also recommended, for which purpose and how it works in this case, we will understand a little more. The fact is that the main source of ATP is glycolysis, the exchange of glucose in cells. And this drug directly affects it, activating and accelerating its enzymes, pyruvate metabolism, the launch of xanthine dehydrogenase, nucleotide synthesis. In addition, it “dilutes the blood” by reducing platelet aggregation, and also improves the regeneration of tissues, especially the myocardium and mucous membranes of the digestive tract.
Special cases
In addition to therapists, obstetrician-gynecologists also often recommend the Riboxin preparation during pregnancy to their patients. For what and what is the effect of this, let's figure it out together. First, it must be remembered that during the development of the fetus, its tissues are provided with oxygen and nutrients exclusively from the mother's body. And therefore, if the mother has anemia or diseases of the internal organs, her own metabolism does not cope with the needs of both of her - her and the baby growing inside. And then it’s worth resorting to the Riboxin preparation during pregnancy, for which doctors recommend it. Since it is first of all necessary to provide comfort for the correct laying of organs and the development of the child, it will depend on how he is born and grows up. And therefore, if the obstetrician-gynecologist allows you to take this drug and sees your testimony for its use, then you should not be afraid, because the baby’s health is in your hands, especially when it is still developing inside you, dear future mothers.
Contraindications
In general, the drug is quite safe, however, it is necessary to refuse to take it if the patient has hypersensitivity to its components, renal failure and gout. This is because side effects, even when taking a therapeutic dose (and even more so), are allergic reactions (hyperemia and / or itching of the skin), hyperuricemia (increased amount of uric acid in the blood), which leads to exacerbation of gout and damage to the kidneys. In other cases, the drug is safe and actively recommended by doctors.