The drug "Ksefokam" application instructions refers to the pharmacological group of drugs - non-narcotic analgesics. It is also produced under the alternative name Lornoxicam.
The main active ingredient of the drug is lornoxicam, under the same name the drug is classified according to the INN registry.
Lornoxicam is indicated for diseases such as arthritis of various etiologies (acute gouty, rheumatoid, psoriatic), effective in treating lupus erythematosus, which proceeds in a mild form, not burdened by renal complications. Ksefokam instructions for use recommends for the treatment of deforming osteoarthritis, accompanied by inflammation of the synovial membrane and periosteum, ankylosing spondylitis. As a therapeutic, prophylactic and restorative agent, it is used in the postoperative or post-traumatic period.
The drug "Lornoxicam" has the following contraindications for use. It can not be used in the presence of any hypersensitivity to the components of the drug. It is not recommended that patients with diagnosed diseases of the gastrointestinal tract use gastric and duodenal ulcers, with gastric bleeding, and functional disorders of the kidneys and liver. Ksefokam does not recommend use for patients with diseases: bronchial asthma, leukopenia, thrombocytopenia, heart failure and complex forms of arterial hypertension. It is recommended to stop taking the drug during pregnancy and breastfeeding, and should not be used to treat patients under the age of 18 years and the elderly.
When taking Xefocam medication, the instructions for use indicate the possibility of side effects. Such can be nausea, vomiting, possibly causing heartburn and pain in the epistragal region, flatulence, diarrhea. When taking the medicine, erosive and ulcerative lesions and the development of gastritis are possible, up to bleeding from the gastrointestinal tract. When using the drug in the form of injections, allergic reactions, rashes at the injection site, painful sensations are possible.
If negative effects of the gastrointestinal tract occur during the use of the Lornoxicam preparation, then it is recommended that the drug be taken with misoprostol simultaneously. Xefocam tablets increase the hypoglycemic activity of preparations containing sulfonylurea derivatives, and at the same time affect the effectiveness of antihypertensive drugs. Lornoxicam reproduces the renal digoxin of chlorine in the body, contributes to an increase in the concentration of lithium elements. If the medicine is taken together with cimetidine, the latter helps to increase the concentration of xefocam in the blood.
With an overdose of the drug, side effects from the gastrointestinal tract may increase, a significant increase in blood pressure, and even the occurrence of heart and kidney failure, is also possible.
To minimize the negative consequences of an overdose, it is recommended to wash the stomach, take activated charcoal. In this case, dialysis should not be resorted to, it is usually ineffective.
Lornoxicam tablets are taken before meals, it is recommended to drink them with a sufficient amount of liquid. The rules for using the drug in the form of injections are detailed in the instructions for its use.
In all circumstances, safety precautions should be observed. If the medicine is used nevertheless in the presence of erosive-ulcerative lesions, xefocam should be taken only in combination with H2-blockers.
The medicine “Lornoxicam” is also produced under the name “Xefocam Rapid”, the instruction to which determines the properties of this derivative by concentration as higher in comparison with the drug “Xefocam” and by bioavailability as identical to those of “Xefocam”.