This publication is about Anauran (ear drops). The instruction reports that this tool is a combined preparation intended for topical use. The medicine has an antibacterial as well as a local anesthetic effect.
The medicine "Anauran" (drops), due to the content of neomycin sulfate (an aminoglycoside antibiotic) in it, has a bactericidal effect against such gram-positive microorganisms as Streptococcus pneumoniae, Staphylococcus spp., As well as gram-negative: Shigella boydii, Proteus spp., Escherichia coli, Shigella sonnei, Shigella flexneri, Shigella dysenteria. The drug is inactive in relation to Streptococcus spp.
About another polypeptide antibiotic - polymyxin B, which is also part of Anauran drops, the instruction reports that it is active against the following gram-negative microorganisms: Salmonella typhi, Shigella flexneri, Salmonella paratyphi, Pseudomonas aeruginosa, Escherichia coli. In relation to fungi and gram-positive cocci, as well as Mycobacterium spp. and Proteus spp. polymyxin B does not show activity.
Drops are characterized by a weak local irritating effect. Pain and itching that accompany the inflammatory process are eliminated for a short time by the local anesthetic lidocaine, which is also part of the drug in question.
Regarding the pharmacokinetic studies of the Anauran drug, the instructions for its use report that they were not carried out due to the local use of the drug and the low likelihood of systemic effects. The considered ear drops are used for acute / chronic external otitis media, moderate acute otitis media at the stage preceding perforation. The drug is effective in the treatment of purulent complications in the postoperative period. We are talking about such operations as tympanoplasty, radical mastidectomy, fenestration, anthrotomy.
To use the medicine Anauran (ear drops), the instruction recommends as follows: with the help of a special pipette, the drug is instilled into the external auditory canals. After such a procedure, it is advisable to tilt your head down and hold for several (2-3) minutes. For the treatment of adults, 4-5 drops should be dripped from two to four times a day. Children receive the medicine with the same frequency, but in a twice reduced dosage - 2-3 drops per procedure. Dosage depends on the severity of the pathology. The course of treatment with the drug "Anauran" instruction recommends discontinuing after seven days.
Like other drugs, the described drug has a number of contraindications. You should pay attention to the composition of the ear drops. In the presence of hypersensitivity to one of the components of the combined drug, it is forbidden to use it! As for the treatment with these ear drops during pregnancy, strict medical supervision is necessary. The same applies to the lactation period. The same applies to children under one year of age - treatment with the considered ear drops is carried out only if there is an urgent need for their appointment (exclusively under medical supervision).
Special instructions that you should pay attention to when using the Anauran drug: the instruction clarifies that these drops are intended solely for the treatment of ear diseases. If severe, persistent infections occur, then in addition to local, an additional systemic use of antibiotics is carried out. With prolonged use of antibiotic drugs, including Anauran drops, it is possible to develop infections provoked by drug-resistant microbes. Cases of overdose with these ear drops are not described.
Giving a description of the drug "Anauran", the instructions for use name incompatible medications with it. These are such drugs as Netilmicin, Gentamicin, Streptomycin, Monomycin, Amikacin.
Released by prescription.