Life is complex and diverse. Modern man lives in a frantic rhythm: from morning to evening he is engaged in solving various kinds of problems, complex and not very, communicating with a mass of people (and by no means always the process of communication goes smoothly and without excesses). Such a cycle of events every day for a long period of time is able to bring the human nervous system to exhaustion. And now, from a calm and friendly person, the individual suddenly became nervous and explosive, and resistance to stress decreased significantly.
It’s hardly possible to get out of such a vicious circle independently. It is likely that the use of antipsychotics, in particular the drug Truxal, may be required.
Antipsychotics: what is it
Antipsychotics refers to medications that have antipsychotic properties. Simply put, these drugs can significantly reduce or even eliminate the manifestations of the productive symptoms of psychosis. The bulk of antipsychotic drugs, in addition to their main functions, can have sedative (sedative, hypnotic) and anxiolytic (anti-anxiety) effects.
The modern pharmaceutical market is ready to offer its patients and medical specialists the widest selection of drugs such as antipsychotics. The classification of these drugs is as follows. Medicines can be assigned to the group of typical antipsychotic drugs or to the group of atypical ones. The first group includes phenothiazines (aliphatic, piperidine and piperazine derivatives), butyrophenones and thioxanthenes.
The atypical group includes tricyclic antipsychotics derived from sulfonylbenzamide, indole (reserpine). The last component of the group is diphenylbutylpiperidine.
In addition to such grouping, in these drugs (antipsychotic drugs), classification is possible according to the activity of the effect relative to the effect exerted by the chlorpromazine on the human body. There may be 4 subgroups:
- drugs with a weakened effect;
- drugs of medium power, approximately similar to chlorpromazine;
- medicines with increased antipsychotic activity;
- powerful antipsychotics.
The scope of antipsychotic drugs is the treatment and prevention of schizophrenia and other mental disorders. In addition, these medicines are widely used as antidepressants. There is a practice of using antipsychotics in the treatment of anxiety-psychotic exacerbations, the appearance of symptoms of delirium and hallucinations. The drug gives a good effect in the treatment and rehabilitation of patients after traumatic brain injury. The most common and common side effects are expressed in daytime sleepiness, lethargy, and emotional indifference.
What is Truxal
Truxal is a neuroleptic drug that is prescribed by medical professionals to treat a wide range of mental disorders. This may be some temporary disturbances provoked by the influence of external factors, but anomalies can also be treated during the development of the central nervous system.
Under the influence of the active active component of the drug - chlorprotixen - the internal balance and calm are effectively restored, and the state can be significantly improved in severe mental disorders.
The principle of action is the ability to block the work of dopamine receptors (participate in the processes of learning, motivation, coordination of fine motor skills). Truxal tablets have a general sedative effect with a fairly wide symptomatology and the presence of concomitant diseases, which is due to the drug’s ability to block the work of adrenergic receptors (adrenergic receptors) in the brain stem.
In addition to the main active ingredient, Truxal includes auxiliary substances: lactose, corn starch, microcrystalline cellulose, 85% glycerin, talc, copovidone, magnesium stearate.
Indications and contraindications for taking the drug
"Truxal" instructions for use defines as a drug for a fairly wide range of patients, not only with diagnosed psychoses, accompanied by psychomotor agitation, anxiety and anxiety. This medication can also be recommended for schizophrenia, various kinds of neurosis, depression, which have become protracted. “Truxal” is effective in relieving withdrawal symptoms (alcohol and drugs), in treating brain injuries, in stopping mental manifestations that can accompany various diseases of internal organs (tension, insomnia, anxiety).
In addition, Truxal has indications for use and, in the presence of diseases such as epilepsy and oligophrenia, successfully relieves pain, enhancing the effect of analgesics. In elderly patients, the drug effectively eliminates excessive irritability, hyperactivity, anxiety, and mental agitation. In some cases, it can be prescribed to children over 3 years of age with behavioral and sleep disorders, the presence of discirculatory encephalopathy, gastrointestinal tract spasms (GIT).
Still, as the reviews declare, Truksal can be appointed by medical specialists in the postoperative periods, previously before taking a large number of strong medicines, with severe itching.
Like any medication, Truxal has its own list of contraindications. As a matter of course - individual intolerance to the main active substance - chlorprotixen. Further, the Truxal medicine is contraindicated in patients with circulatory collapse (convulsive seizures, coma) and in people whose central nervous function is weakened by any external factors (taking alcohol, drugs, etc.).
Another of the most formidable contraindications can be called any blood pathology, myasthenia gravis (fatigue of striated muscles), pheochromocytoma (APUD system tumors, can be either benign or malignant), the presence of closed angle glaucoma.
For children under 3 years of age, the drug is also contraindicated.
When to be careful
In addition to unambiguous contraindications for taking the drug "Truxal", the instructions for use indicate some diseases and situations where administration is possible, but with caution, as directed by a doctor and under his supervision. Such diseases include convulsive disorders, problems of the cardiovascular system, prostate hypertrophy, a predisposition to the development of glaucoma.
When diagnosing any abnormalities in the functioning of the kidneys and liver, Truxal should also be taken with caution, taking an individually tailored dose and constantly monitoring the condition of the diseased organ. Attentive to their condition should be elderly patients, people with respiratory disorders caused by asthma or infectious diseases. The presence of a stomach ulcer or duodenal ulcer, urinary retention are also sufficient grounds to be careful about taking the drug.
With caution, Truxal tablets are recommended for those who need to take large doses of potent drugs during treatment for other diseases.
Possible side effects and interactions with other medicines
Like any medicine, Truxal can cause side effects from various organs and systems of the body. For example, the nervous system can respond to a medication by the occurrence of lethargy, akathisia (a person’s inability to remain motionless, the need to often change his posture, move), dizziness, dystonic reactions (uncontrolled movements).
The reaction of the cardiovascular system can manifest itself in tachycardia (heart rate more than 90 beats per minute) or hypotension (increased blood pressure). If you study consumer reviews, Truxal can sometimes cause deviations in the functioning of the sensory organs. Possible side effects from the digestive system. In rare cases, abnormalities in the hematopoietic, urinary and endocrine systems can be seen.
Treatment of adverse events is symptomatic. If there are reactions that threaten the patient's life, it is necessary to do a gastric lavage, then take the maximum possible dose of absorbent material (usually activated charcoal) and treat all associated manifestations.
As for the interaction with other medications, we can say about some of the identified patterns. The drug "Truxal" is able to enhance the influence of drugs that depress the central nervous system, alcohol and drugs. Concomitant use with drugs that increase blood pressure can enhance the effect of these medications. Medicines that lower blood pressure may not have enough effect. Typical antipsychotics in combination with Truxal can provoke brain intoxication. The antihistamine properties of the drug can significantly weaken the effect of alcohol on the body.
Excess dose
The dose that can be taken during the day is from 15 to 300 mg, depending on the patient’s state of health. Overdose of the drug "Truxal" instructions for use describes the symptoms of various organs by various organs. Depending on the amount of medication taken, fluctuations in body temperature, drowsiness, confusion, and the inability to concentrate on anything are possible. In severe cases, the onset of shock, convulsions, coma (life-threatening condition) is possible. The cardiovascular system, as with the manifestation of side effects, can respond to an overdose with increased heart rate, lowering blood pressure.
In order not to become a hostage to the negative situation when Truxal is taken in combination with some other medicines, some nuances must be taken into account. If the dose is exceeded, the dialysis procedure will not produce tangible results. It is unacceptable to take a medication in combination with adrenaline. Convulsive conditions, experts recommend taking with the drug "Diazepam". The drug “Truxal” is not recommended to be taken in the process of carrying out any risky work (driving a car, high-altitude manipulations, etc.)
Pregnancy and lactation
If possible, experts recommend limiting the use of Truxal during pregnancy and breastfeeding. However, if situations arise where the need for treatment exceeds the possible risks from side effects, then Truxal (instructions for use describes the acceptable dose and dosage regimen) can be taken. In this case, newborn babies at first may be slightly apathetic or, conversely, hyper-excitable. At a conscious age, such children may have low self-esteem.
If it is necessary to take Truxal during lactation (this can be done in extreme cases), the amount of medication in breast milk can reach 2% of the daily dose.
Release form and price range
At present, the manufacturer is ready to offer Truxal to consumers in three forms of release. In pharmacies, you can buy 5 mg tablets, coated and in a package of 50 pieces. The drug in 25 mg tablets (also coated) are sold in packs of 100 pieces. And the drug in 50 mg film-coated tablets is packaged in a pack of 50 pieces.
The cost of a package of 50 tablets of 5 mg each ranges from 380 rubles to 470. It should be noted that such packages are found in free sale quite rarely. A pack of 50 tablets of 50 mg each will cost the buyer from 435 to 520 rubles. And 100 tablets of 25 mg can be purchased for 375-465 rubles.
Analog medicines
All analogues of Truksal are the only Chlorprotixen available to a wide range of consumers. Both drugs, both Truxal and Chlorprotixen, contain certain doses of the drug substance chlorprotixen.
Before you opt for the drug itself or its analogue, you should familiarize yourself with the available pros and cons of Chlorprotixen. This analogue of the drug “Truxal” has a lower price than the main drug. In tablets, the drug can be offered to customers with a dosage of 15 mg in packs of 30 and 50 pieces and a dosage of 50 mg also in packs of 30 and 50 pieces. The price range is as follows:
Dosage (mg) | The number of tablets in the package (pieces) | Packing cost (rub.) |
15 | thirty | 165-230 |
15 | fifty | 250-310 |
fifty | thirty | 250-310 |
fifty | fifty | 400-450 |
Chlorprotixen is not available in a dosage of 5 mg. There are differences in the form of release of drugs, namely, “Chlorprotixen” is offered to consumers not only in tablets, but also in the form of injections.
For a pregnant woman and a nursing mother, it is preferable to take Truxal. This is probably due to the presence of 5 mg tablets. Well, as reviews describe, Truxal has a less effective therapeutic effect than its counterpart.
The opinion of patients and specialists
Based on the reviews about Truxal, certain advantages and disadvantages of the drug can be identified. The pluses include the fact that the results of the treatment course can be called satisfactory, with positive dynamics. Perhaps the appointment of future and nursing mothers, children. Side effects are rare.
The negative factors include the fact that there is an analogue of the drug Truksal, the price of which is lower than that of the main medication. In addition, different experts interpret the concept of acceptable dosage differently.
A separate group of people conducted a treatment course using Truxal to their children. Many of the parents spoke out in favor of the drug in that children became much easier to study at school and to do homework on their own. At the same time, the sleep-wake cycle was normalized in many children.
However, regarding childhood, everything is individual. Although Truxal has indications for use for children, some parents were unsatisfied with the effect. One of the small patients became very inhibited, and when the doctor prescribed Truxal in combination with the glycine and adaptol medicines, the child developed hyperactivity and restlessness.
At medical experts, reviews have a slightly different focus. Doctors believe that a medication can bring a fairly effective result if the patient's body responds correctly to it. For this, treatment should be carried out in parallel with regular examinations and tests to select the optimal dose of the drug. In general, among specialists, the drug has positive reviews. Truxal is quick and effective enough to cope with neurotic, depressive and schizophrenic conditions. According to doctors, most of the side effects are psychogenic in nature. If the symptoms of the disease are not very pronounced and its development is not of high intensity, it is best to start taking the drug with minimal doses.
Considering the fact that Truxal is not able to cause drug dependence or the addiction effect, it can be used for the treatment of many mental disorders for a rather long period of time. However, this does not mean that you can assign it to yourself. Whatever flattering characteristics the acquaintances and neighbors may give to the Truxal drug (price, instructions are not decisive in such cases), this drug (as, indeed, all other antipsychotic drugs) should be taken under the strict supervision of a doctor and only with his permission.