Scientists have fully disclosed the question of what an allergic reaction is at the cellular level, talked about the types of allergens and the types of reactions to them. But why one person is more susceptible to the same factors, why some simple things can cause such a violent reaction in the body that serious treatment is required with a threat to life, and the other does not happen, it is still not possible to find out. For proper treatment of allergies, you need to consult a doctor and determine which allergy pills are right for you.
The article will talk about predisposing factors to allergies, its types, and most importantly, about the modern approach to the treatment of tablet forms of release with antihistamines.
Why is allergy in the world progressing
There are a large number of factors that provoke allergies. Many associate this disease with the progress of mankind:
- Environmental degradation in the world negatively affects human health - this is one of the main factors. People living in the city daily breathe car exhaust and industrial emissions. This explains the higher incidence rate in megacities than in remote towns and villages.
- The not always justified amount of medications taken, a large number of household detergents, cosmetics, perfumes, the use of insecticides, herbicides and pesticides in agricultural business could not but affect human health due to the high allergenicity of all these chemicals.
- Heredity is an important factor in the development of allergies, very often individual sensitivity to something is transmitted to a person from his previous generations.
- And, of course, the health of the digestive, nervous, endocrine systems, climate, lifestyle and the nature of nutrition play a big role.
The convenience of tablet forms
The best thing you can do to avoid allergies is to limit contact with allergens or stop eating them. Of course, this only applies to cases where you are aware of this allergen. It often happens that it is impossible to protect yourself from unpleasant manifestations that interfere with normal life. For example, in the case of seasonal rhinitis or allergies to flowering, only moving to another city or country will help. Naturally, far from all have this opportunity.
To stop an allergy attack will help drugs that you can take or take with you at any time to use at the right time. Antihistamines in tablet form will be very convenient. So which drugs are better to use in case of an allergy attack?
Allergy pills: 4 generations of drugs
Today in the pharmacy you can buy drugs of four generations, the action of which is aimed at reducing the excessive production of histamine, that is, antihistamines. The newer ones - the third and fourth generation - have many advantages, but do not forget about the first generations: there are cases when their use is more justified.
First generation | Second generation | Third generation |
"Diazolin" "Suprastin" Tavegil Fenkarol | Fenistil Claritin Loratadin Semprex Kestin Histalong | Telfast Fexofast Fexadin Zodak Tsetrin "Parlazin" Xizal Gletset "Suprastinex" Erius "Desal" |
What is the difference between generations of antihistamines
Note the main differences:
- 1st generation. The main shortcomings of the first generation of drugs are side effects: drowsiness after taking, tachycardia, the need to take 2-3 times a day, addiction, which requires a constant change of one drug to another.
- 2nd generation. These drugs do not cause drowsiness and exceed the previous generation in effectiveness, but can negatively affect the myocardium and cause arrhythmia.
- 3rd and 4th generation. According to the instructions for use, tablets from allergies of the latest generations are relatively safe in terms of side effects, do not have a sedative and cardiotoxic effect.
Indications for use
Allergy pills can be used in the following cases:
- year-round or seasonal allergic rhinitis, sneezing, bronchospasm;
- allergic conjunctivitis;
- rash, itching, redness on the skin;
- contact and atopic dermatitis in complex therapy.
First generation drugs
First-generation drugs “Diazolin", "Suprastin", "Tavegil", "Fenkarol" should not be written off, because, despite the above disadvantages, they still find application and even are in our home medicine cabinet.
"Suprastin" and "Tavegil" are not only available in allergy tablets. These drugs have an injectable form, which means that they can be used for urgent relief of an allergy attack: for example, as first aid for Quincke's edema or anaphylactic shock. These drugs are often used for skin forms of allergies, with severe itching, their sedative effect has a positive effect. The quick action and low cost of allergy pills determine their widespread use today.
In addition, first-generation drugs are part of many combination medicines (for example, for colds, sleeping pills and others) and have been used to treat motion sickness, migraine and anxiety.
Second generation drugs
Compared with first-generation drugs, Fenistil, Claritin, Loratadin, Semprex, Kestin, and Histalong drugs have a longer effect due to slower excretion from the body. Relatively weakly pass through the blood-brain barrier, therefore drowsiness is caused only in particularly sensitive individuals.
According to the instructions for allergy pills, the negative effect of antihistamines on the heart muscle is enhanced in combination with antifungal drugs, some antibiotics and antidepressants. In addition, these drugs can not be washed down with grapefruit juice.
A positive aspect of second-generation drugs are topical forms.
The benefits of a new generation of antihistamines
Which generation of allergy pills to choose? Allergy medications must act quickly and continuously, have a minimum of side effects and not interfere with a normal lifestyle. The third and fourth generation of drugs fully meet all the requirements.
Let's look at a new generation of antihistamines. The benefits of the best allergy pills:
- Preparations of this generation are active metabolites of the funds of the previous row.
- The effectiveness of its predecessors is two to four times greater than this generation.
- They do not have a hypnotic effect, do not have a negative effect on the heart and blood vessels. Acting selectively, only on H1-histamine receptors, do not cause dry mouth and blurred vision.
- Eliminate all negative manifestations of allergies, have a decongestant, anti-inflammatory and antipruritic effect.
- Reception only once in 24-48 hours, the effect occurs within an hour, do not cause addiction, in some cases, therapy can be continued even for several months.
- Eliminating all types of allergies, have a minimum of side effects.
Preparations 3 and 4 generations
The list of new generation allergy pills includes the international nonproprietary name and the names under which they can be bought at the pharmacy. They have different forms of release for ease of use: drops, syrups, tablets. Consider the features of drugs based on each active substance:
- Fexofenadine. "Telfast", "Fexofast", "Fexadin". Available in tablets for allergies to adults at 120 and 180 milligrams. Contraindicated in children under 12 years of age (if there are no other antihistamines, children under 6 years of age can be given a dosage of 60 mg for 2 doses per day). Use with caution in patients with kidney problems. It is strictly forbidden to pregnant and lactating women. In a dosage of 120 mg is prescribed for adults with allergic rhinitis, 180 mg in tablets for allergies to the skin.
- Cetirizine. "Zodak", "Zirtek", "Tsetrin", "Parlazin" in tablets of 10 mg of active substance.
- Levocetirizine. "Xizal", "Gletset", "Suprastinex" in 5 mg tablets. Many of these drugs come in three forms: oral drops, tablets, and syrup. The action in 50% of cases occurs 12 minutes after administration, in 95% - after 1 hour. By agreement with the doctor, drugs can be taken up to six months (for example, with chronic urticaria). Excreted by the kidneys, it is therefore recommended that patients with renal failure and the elderly use with caution.
- Desloratadine. "Erius," "Desal." Available in coated tablets for allergies to adults and children under 12 years of age. "Erius" is available in the form of syrup, and "Desal" - in the form of a solution for oral administration. Preparations in the form of tablets are allowed from the age of 12, 1 tablet per day, regardless of food intake. Syrup "Erius" can be used for children from 1 year. Drugs are contraindicated for pregnant and lactating, with caution - for patients with renal failure. Clinical trials in the use of drugs for children under 1 year have not been conducted. It is believed that rhinitis in children under two years of age does not have an allergic nature, therefore it is rather difficult to differentiate at this age. It is better to take tablets from allergies of this group at the same time and drink them with water without chewing. Alcohol during treatment should not be consumed. The drugs do not affect the speed of the reaction, therefore, driving vehicles during the course is allowed.

Original new generation drugs and drug manufacturing plants
The preparations Telfast, Zodak, Xizal and Erius are original imported drugs, that is, their active substance was synthesized by the first of all other trade names. The pharmaceutical manufacturing company conducted all the necessary clinical trials on them. For a long time, such drugs were protected by a patent. All other drugs of these groups are called generics, that is, "repetitions", "copies". There are very good “repeats” that are more affordable: for example, generics from factories in Belgium, the Czech Republic, Poland, France and other European companies enjoy confidence.
Allergy pill reviews
From the reviews of allergy medications, it can be concluded that the use of first-generation medications is not recommended for customers with seasonal allergies. These drugs affect the quality of normal life: when using them, it is forbidden to drive a car, they cause severe drowsiness. Prices for allergy medications range from 60 to 600 rubles.
Customers who cannot afford expensive treatment choose second-generation drugs, Claritin is especially in demand for its long-term effect, average cost, and the ability to give children and the elderly. This drug affects the functioning of the heart less than others and does not cause drowsiness. The drug "Fenistil" is popular for its versatility.
More and more people learn about drugs of the latest generations and choose the right tablets among them. Many talk about their safety and effectiveness. For example, “Zirtek” copes with itchy skin, “Telfast” can be used for a long time without damage to health. Cheaper is Fexofenadine. The drugs "Cetrin" and "Erius" are considered the safest and most effective.
In conclusion of the article
In conclusion, we summarize. In the pharmaceutical market there are a large number of types of allergy pills. Do not forget that they only relieve symptoms, but do not treat the cause. Be sure to visit a specialist, take the necessary tests to prescribe the right treatment and identify the cause of the symptoms.