In the article, we consider the instructions for use and reviews of "Rulid".
In some infectious diseases of bacterial origin, without additional administration of antibacterial agents, there is no positive dynamics of the pathology. The Rulid medical product, which is an antibiotic from the macrolide group, is highly effective. It is used for a variety of infectious pathologies of the respiratory system, digestive and genital organs, and is also actively involved in dentistry.
pharmachologic effect
According to the instructions for use with Rulid, this semi-synthetic antibacterial agent of the macrolide group is active against the following pathogens:
- Moraxella (Branhamella) catarrhalis;
- Bordetella pertussis;
- Campylobacter jejuni;
- Borrelia burgdorferi;
- Methi - S - Staphylococcus;
- Campylobacter coli;
- Gardnerella vaginalis;
- Chlamydia trachomatis, psittaci and pneumonia;
- Rhodococcus equi;
- Mycoplasma pneumoniae;
- Clostridium spp .;
- Propionibacterium acnes;
- Corynebacterium diptheriae;
- Peptostreptococcus spp .;
- Enterococcus spp .;
- Porphyromonas spp .;
- Neisseria meningitidis;
- Lysteria monocytogenes obiluncus;
- Helicobacter pylori;
- Legionella pneumophilia;
- Streptococcus pneumonia;
- Pasteurella multocida;
- Streptococcus spp.
Moderately sensitive to this drug: Ureaplasma urealyticum, Haemophilus influenza and Vibrio cholerae.
Resistant to it: Pseudomonas spp., Acinetobacter spp., Enterobacteriaceae, Mycoplasma hominis, Methi-R Staphylococcus, Fusobacterium, Nocardia, Bacteroides fragilis.
Composition and form of release
As indicated by the instructions for use, "Rulid" is available in the form of round white tablets for oral use, as well as in the form of tablets for the manufacture of a suspension for children. The active component of the drug is the synthetic substance roxithromycin, which exhibits a systemic effect and is active against gram-positive and gram-negative bacteria. The destructive effect is observed in relation to streptococci, mycoplasma, staphylococci, chlamydia, pertussis bacillus, listeria, meningococcal infection, diphtheria bacillus, ureaplasma.
Excipients
In addition to the main element, the chemical formula of this medication contains some auxiliary substances, which include magnesium, povidone, hypromellose and dextrose. They are used to enhance the healing effect. It is allowed to take an antibiotic only in those cases when it was prescribed by a specialist, self-medication is excluded.
What else does the application instruction for Rulid tablets tell us?
Indications for use
The scope of the considered antibacterial drug includes infection of all parts of the respiratory tract, which means that Rulid is prescribed for acute forms of such pathologies as bronchitis, pneumonia, whooping cough, otitis media, sinusitis, tonsillitis, laryngitis, frontal sinusitis, etc. Other medical indications for use:
- diseases of the skin or soft tissues of infectious origin (furunculosis, pyoderma, erysipelas);
- infections of the oral cavity, gums and teeth (periodontitis, periodontal disease);
- infection with a urinary or genital tract infection (vaginitis, cervicitis, urethritis, syphilis, endometritis);
- bone tissue pathology (periostitis, osteomyelitis);
- diphtheria, trachoma, scarlet fever, brucellosis;
- preventive use after surgical interventions, during dental procedures, etc.
This antibiotic purposefully affects the focus of inflammatory pathology, providing a quick recovery of the patient. This is confirmed by the instructions for use attached to the drug "Rulid".
Contraindications
This medicine is prohibited in the following cases:
- pregnancy, lactation;
- age up to 2 months;
- hypersensitivity to the active elements of the antibiotic;
- liver failure.
Side effects and overdose
According to the instructions for use and reviews of "Rulid", when carrying out antibacterial therapy with this medication, some adverse reactions may occur. In this case, the patient needs to suspend treatment, consult a doctor for advice. The following changes in well-being should be alert:
- acute abdominal pain, cramping, vomiting, upset stool, nausea;
- symptoms of acute hepatitis, changes in the composition of the blood;
- migraine attacks, increased nervousness, dizziness;
- hemorrhagic rash, itching, redness, swelling of the skin;
- loss of taste.
With such anomalies, it is recommended to stop taking the medicine "Rulid", replacing it with a milder analogue with a similar effect on the focus of inflammation.
Cases of drug overdose are also possible, and they are manifested by excessive intensity of side effects. In such cases, therapy should be urgently discontinued, gastric lavage and sorbent preparations taken. Further therapy should be symptomatic.
The application instruction for Rulid does not end there.
Method of use and dosage of medication
This antibiotic is intended for oral use, while a single dose is washed down with plenty of water, and the tablets are swallowed whole. It is recommended to take the medicine before eating.
So it is said in the instructions for use for tablets "Rulid" (for adults) 0.
In childhood, with a child weighing more than 40 kg and adults, a single dose of the drug is 150 mg, and a daily dose of 300 mg. Take medicine at an interval of 12 hours. As for patients with kidney and liver pathologies, they are allowed to take this drug in small doses, divided into two doses - no more than 150 mg of roxithromycin per day.
For children under 4 years of age, this antibacterial agent is prescribed extremely rarely, and the dosage is calculated individually.
Drug interaction
In accordance with the instructions to "Rulid", during antibiotic therapy, it is necessary to control the use of other medical devices. For example, in combination with Terfenadine, ventricular arrhythmia can occur, and when treated with Astemizole, Cisapride, and Pimozide medicines, there is a change in the chemical composition of the blood, lengthening of the QT interval and severe cardiac arrhythmias, as a result of an increase in their serum concentration.
There is no interaction with the drugs "Warfarin", "Ranitidine", as well as with antacids and hormonal contraceptives.
With the concomitant use of roxithromycin with vitamin K antagonists, it is necessary to monitor prothrombin time.
With simultaneous use with the drug "Digoxin" may increase the absorption of the latter. In this case, it is recommended to follow the indications of the electrocardiogram and the level of glycoside.
Roxithromycin increases the elimination period of midazolam, which leads to an increase and prolongation of its effect.
This describes the instructions for use.
Analogues of "Rulida"
Any antibiotic of the macrolide class can be analogues of this medication, the group of which includes:
- "Azivok";
- "Azimycin";
- Azitroks
- "Azithromycin";
- “Binoklar”;
- "Brilid";
- "Wilprofen";
- "Zitrolide";
- Isolon;
- Clubax
- "Klacid";
- Claritrosin;
- "Rovamycin";
- "Rulitsin";
- Sumazid
- Sumaclide;
- "Sumamox";
- "Fromilide";
- Hemomycin;
- Ecomed;
- "Erythromycin";
- Ermicid.
"Roxyhexal" is an antibiotic intended for the treatment of skin diseases, pathologies of the urinary system, tonsillitis, pharyngitis and other respiratory ailments.
"BD-Rocks". This tool treats diseases of the skin, malfunctions in the normal functioning of the genitourinary system, pathology of the respiratory tract, and is also effective for meningitis, syphilis or other sexually transmitted diseases.
"Roxibel" is a good analogue, it also helps to heal skin diseases, for example, various inflammations, furunculosis, prostatitis, and respiratory ailments.
Rulid: suspension for children
This drug with high effectiveness is prescribed not only for adults and elderly patients, but also for children. In this case, pediatricians recommend it for severe infectious pathologies of the respiratory system and skin in children.
What does the instruction manual for Rulid for children tell us?
This dosage form is a special tablet for dissolution in water to obtain a suspension of the drug. In order to prepare a suspension, it is necessary to remove a tablet of the medication from the package, correctly calculate the dosage for the child, which is determined depending on the patient’s body weight, and dissolve it in the required amount of water. In the package of the drug there is a special measuring spoon, which helps to properly dose the suspension "Rulid". Instructions for use for children indicate that the drug is also used for pathologies such as pertussis, scarlet fever, diphtheria, etc. The duration of antibiotic therapy should not exceed ten days.
Reviews about the drug
The antibacterial agent "Rulid" has a large number of reviews, but for the most part, they are ambiguous, despite the fact that the effectiveness of this medication has long been proven by numerous scientific tests and use in specific patients.
Most people who use this medication are of the opinion that this antibiotic copes well with its tasks - the destruction of various types of bacterial infections, which favorably affects not only the general condition, but also eliminates the specific symptoms of a disease. Since "Rulid" is most often prescribed for pathologies of the respiratory system, the reviews describe many cases of the abatement of inflammatory processes in the form of acute bronchitis, pneumonia, tracheitis, sinusitis, etc. Patients note that already on the second or third day the symptoms of the disease become insignificant and health is significantly improved.
Negative reviews about the drug contain information about its toxicity and intolerance, as well as a large number of adverse reactions that provoke the use of this antibiotic. These include severe diarrhea, which in most cases was the result of an imbalance in the intestinal microflora, candidiasis of the mucous membranes, “thrush” in women, and so on. In such cases, it was necessary either to cancel this drug, replacing it with a milder one on the patient’s body, or to reduce the dosage, which usually did not produce the expected therapeutic effect. In addition, in the treatment with Rulid, it is necessary to use some other medicines that prevent the development of unwanted side effects or eliminate them. Such agents are usually probiotics, antifungal drugs, antidiarrheal drugs, etc.
Reviews of experts suggest that this medication is prescribed with great care, since it is very toxic and dangerous when used in old and childhood. Nevertheless, experts point to its high effectiveness in the treatment of a variety of diseases caused by a bacterial infection. Pediatricians try to refrain from prescribing the Rulid antibiotic to children under six years of age, choosing other, safer drugs. However, in some cases, they still have to do this, but parents are advised to carefully monitor the condition of the child and, in cases of pathological conditions, consult a doctor immediately. And in no case do not stop taking it as soon as it becomes easier (this is true for all antibiotics).
We examined the instructions and analogues supplied with the drug "Rulid".