It is no secret that for patients who suffer from various chronic diseases, it is important to choose a drug that will most effectively remove most of the symptoms of the disease and at the same time have a minimal negative effect on the body. This fully applies to the drug "Nimesil", the instructions for use of which indicate that this tool, which appeared on the shelves of pharmacies relatively recently, is widely used in rheumatology for the treatment of diseases of the musculoskeletal system, for neuralgic pains, as well as for the elimination of febrile syndrome .
The drug "Nimesil" (international name "Nimesulide") - the instructions must be read before treatment
I must say that it was the Nimesil drug, the instructions for use in its first edition did not contain all the known information about this drug, and what is also important, about possible complications, caused the scandal, the echoes of which periodically arise again and again. Firms that introduced the drug to the pharmaceutical market did not indicate that the use of this non-steroidal drug, especially in high doses, may result in toxic damage to the kidneys and liver, especially in children.
But in this case, we can mention that both analgin, and aspirin, and paracetamol should also be used with some caution (especially in the treatment of children), namely, these drugs until the last decade have been most often prescribed in pediatric practice for symptomatic treatment of high temperature. It turned out that the Nimesil drug, the use of which was not controlled by anyone, was banned for sale, and patients with joint pathologies, acute and chronic pain, became hostages of the situation. The shortcomings were eliminated, and the updated instruction in full describes all the indications and contraindications, the dosage regimen and recommendations for taking the drug.
The medicine "Nimesulide" for the treatment of pain and inflammation
The drug "Nimesil", the instructions for use of which is enclosed in each package of this medicine, should not be prescribed to children and adolescents under 12 years of age - in this age group, despite the effectiveness of the drug for the treatment of fever of any origin, the greatest number of complications was noted. In general, from the guidelines for taking the drug "Nimesulide", regardless of the manufacturer, instructions were removed that this medicine can be prescribed to reduce high body temperature.
By its action , Nimesil, the instructions for use of which should be read carefully before starting treatment, most fully manifests its effect precisely in the pathology of joints - diseases of articular cartilage, ligaments, periarticular soft tissues, muscles. This drug has a pronounced anti-inflammatory and analgesic effect precisely due to the suppression of the synthesis of the main inflammatory mediators (prostoglandins) and the slowing down of the pain impulse along the nerve fibers of the spinal cord. In addition, the drug "Nimesil", an annotation to which even from different manufacturers contains similar information, has a protective effect on articular cartilage, protecting it from destruction even under excessive loads and the inflammatory process in the joint.
Modern medical practitioners in any field of medicine advise against using the Nimesulide medicine, regardless of the form of the drug, as an antipyretic drug, precisely because in this case it is necessary to prescribe it in sufficiently high single and daily doses. When using this drug as a basic treatment for arthritis and arthrosis, manufacturers are advised to take the drug immediately before meals, and patients with digestive tract problems should use the drug with caution and only if the doctor recommends it.