The drug "Ketonal DUO" (tablets), the price of which varies within 300 rubles, is an antipyretic, anti-inflammatory and analgesic. The tool is characterized by a double - quick and long - action. After taking the medicine, it is absorbed from the digestive tract quite well. The total bioavailability, which is 90%, is not affected by food intake. About two hours after ingestion, the maximum concentration of the drug is noted. The product has the ability to penetrate well into the synovial fluid, where it persists for at least thirty hours. The breakdown of the drug occurs in the liver, excretion through the kidneys.
Means "Ketonal DUO" (tablets). Instructions for use. Indications
The medicine is prescribed as symptomatic therapy of inflammatory and painful processes of a different nature. Indications also include degenerative diseases in the musculoskeletal system: seronegative, Ankylosing spondylitis (ankylosing spondylitis), psoriatic, reactive, rheumatoid arthritis. The medicine "Ketonal DUO" (tablets), the instructions for use recommends for gout, osteoarthrosis, pseudogout. The indications include manifestations of a pain syndrome against a background of tendonitis, neuralgia, radiculitis, bursitis, as well as headaches, post-traumatic and postoperative pain, and soreness in oncology.
Contraindications
Ketonal DUO tablets are not prescribed for cases of bronchial asthma, urticaria or rhinitis, hypersensitivity to components and other NSAIDs, peptic ulcer, Crohn’s disease in the acute stage, hemophilia and other disorders in the coagulation system, kidney and liver failure. The drug is not prescribed to patients after coronary artery bypass grafting, during pregnancy, with cerebrovascular, gastrointestinal and other bleeding, during lactation. The medicine is contraindicated in children under the age of fifteen, patients with ulcerative colitis. Caution is shown in diabetes mellitus, pathologies of peripheral arteries, cerebrovascular or cardiovascular diseases of a pronounced course, arterial hypertension, a history of bronchial asthma, chronic dyspepsia. Dose adjustment may be required with concomitant treatment with antiplatelet agents, anticoagulants, oral glucocorticosteroids, with prolonged use of NSAIDs.
The drug "Ketonal DUO" (tablets). Instructions for use. Side effects
During treatment, liver, kidney, abdominal pain, stomatitis, anaphylactic edema, gastrointestinal bleeding, speech disorders, hallucinations (when taken in large doses) are likely. The medication can provoke dizziness, bronchospasm, rhinitis, hematuria, nephrotic syndrome, peripheral swelling and other negative consequences.
Dosage regimen
Means "Ketonal DUO" (tablets), the instructions for use recommends to patients from 15 years of 150 mg / day. The medicine is taken after eating or with food. It is not allowed to take more than 200 mg per day.