"Dexamethasone" tablets - a drug that belongs to the pharmacological group of hormonal drugs. It has many effects, it is used to treat external and internal diseases. However, "Dexamethasone" has many side effects, so it is prescribed only if necessary. Abrupt withdrawal of this drug can also lead to a significant violation of vital functions, the main of which will be a decrease in the production of hormones in the adrenal cortex.
"Dexamethasone" tablets has a complex mechanism of action, which affects a fairly large number of body processes. The drug directly affects inflammatory foci, suppressing the basic functions of tissue macrophages and leukocytes, reduces capillary permeability, which is due to the reaction of the biologically active substance histamine. The active substance also reduces the synthesis of leukotrienes, prostaglandins and specific immune antibodies. Depending on the dose, it can act on the metabolic processes of metabolism of fats, carbohydrates, and proteins. The drug stimulates the synthesis of glucose, promotes the capture of essential acids by the kidneys and liver. An increase in blood carbohydrates promotes the release of the hormone insulin by the cells of the pancreas. Dexamethasone tablets stimulate lipolysis due to the obstruction of glucose uptake by fat cells. However, an increase in insulin secretion leads to the breakdown of these substances. The catabolic effect of the drug prevents its long-term use, as a result of which Cushing's syndrome and osteoporosis can develop. Stimulating the production of pepsin and hydrochloric acid can contribute to the development of peptic ulcers.
Systemic use of the drug causes anti-inflammatory, anti-allergic, immunosuppressive, antiproliferative effect.
"Dexamethasone" pills has many indications, due to the many caused effects. Among the diseases that are successfully treated with this drug, Addison-Birmer disease, hypothyroidism, subacute and acute thyroiditis, progressive ophthalmopathy, exacerbation of rheumatoid arthritis, hemolytic anemia, agranulocytosis, malignant tumors, cerebral edema should be noted. The drug has been widely used in resuscitation and traumatology. When foci of inflammation appear after surgery, dexamethasone is also prescribed. The release form in this case is a solution.
The drug has a strict dosage regimen, which is individually selected for each patient. Often it is prescribed once a morning, since at this time it optimally affects the state of the body and practically does not cause general disorders.
"Dexamethasone" pills causes a huge number of side effects that affect almost all body systems. The most severe of them are adrenal insufficiency, steroid diabetes, hepatomegaly, myocardial dystrophy, convulsions, perforation of the cornea, pancreatitis, duodenal ulcer and stomach ulcer, pancreatitis.
Contraindications to Dexamethasone are as follows: hypersensitivity, systemic mycoses, joint injuries of infectious origin, obesity of the last degree, eye diseases of a viral and infectious nature, trachoma, glaucoma. Pregnancy, lactation are periods in which "Dexamethasone" can be used. The dosage should be strictly regulated, and constant monitoring of the condition of the child is also required. If dangerous complications occur, the dose should be reduced until the final withdrawal.