For bacterial infections that affect the respiratory tract, genitourinary tract or other organs, doctors prescribe systemic antibacterial agents. You can get rid of a number of gram-positive or gram-negative microorganisms, alpha-hemolytic streptococcus, mycoplasma, chlamydia and other bacteria with the help of Erythromycin. Analogues of this drug with the same active substance are also effective.
Features of the tool
Erythromycin tablets contain 500 mg of the same active substance. This is an
antibacterial drug belonging to the macrolide group. Its action is based on the fact that it is capable of disrupting the formation of peptide bonds between amino acids and blocking the process of protein synthesis in pathogenic microorganisms. However, it does not affect nucleic acids.
But the active substance erythromycin in the tissues of the body is unevenly distributed. It accumulates in the kidneys, liver and spleen. The concentration of the antibiotic in urine and bile is several times higher than in blood plasma. Erythromycin is able to penetrate well into the tissues of the lymph nodes, lungs, exudate of the middle ear, sperm, prostate secretion, synovial and ascitic fluid, and the pleural cavity.
Indications: in what cases the drug is prescribed
Before you look for analogues of "Erythromycin", you need to understand the indications for taking this drug. It can be used in cases where the disease is caused by microorganisms sensitive to this antibiotic. We are talking about the following pathologies:
- scarlet fever;
- gonorrhea;
- diphtheria;
- conjunctivitis in newborns;
- trachoma;
- brucellosis;
- whooping cough;
- erythrasma;
- upper respiratory tract infections (bronchitis, tracheitis, pneumonia);
- primary syphilis;
- Genitourinary infections in expectant mothers;
- uncomplicated chlamydia;
- Infectious lesions of the ENT organs (otitis media, sinusitis, tonsillitis);
- Bacterial lesions of the biliary tract (cholecystitis);
- eye infections (problems with the mucous membrane);
- pustular formations on the skin, pressure sores, trophic ulcers, burns.
Patients with rheumatism use the erythromycin (analogues of the drug are also suitable) to prevent the development of streptococcal infections. It is also prescribed for dental operations, during preoperative preparation, before endoscopy.
Possible substitutes for funds
If the doctor, prescribing treatment to the patient, says that a drug with the active substance erythromycin is needed, then a person can choose the most suitable remedy for him in the pharmacy.
It can be enteric coated erythromycin tablets. Also, the pharmacist can recommend the drug "Erythromycin-LECT", "Erythromycin Phosphate." Also on sale you can find the preparations "Erifluid", "Erythromycin-Ferein", "Synerit", syrups "Grunamitsin", "Ilozon".
If necessary, the doctor may prescribe systemic antibacterial agents with another active substance. This is done in cases where the patient has contraindications to taking drugs made on the basis of erythromycin. The following antibiotics can be prescribed: Klacid, Macropen, Sumamed, Fromilide, Azithromycin, Azax, Zitrolide.
List of contraindications
Before you start drinking the original drug or analogues of "Erythromycin", you need to find out if you can use such funds. After all, the list of situations in which they should be abandoned is quite wide. The most common include:
- lactation period;
- hearing loss;
- established hypersensitivity to erythromycin;
- the need to take funds "Astemizol" or "Terfenadine."
If there was a history of jaundice, arrhythmias, renal or liver failure, lengthening of the QT interval on the cardiogram, then it is also better to replace it.
Registered complications when taking the drug
Refuse to use the drug is necessary if any side effects occur. In this case, it is desirable to choose analogues of "Erythromycin" with another active substance. Among the side effects may be:
- skin reactions (rash, urticaria);
- eosinophilia, increased activity of hepatic transaminases;
- diarrhea, nausea and vomiting;
- pain in the abdominal region;
- pseudomembranous enterocolitis;
- cholestatic jaundice;
- the appearance of tinnitus;
- hearing loss;
- in some patients, tachycardia and ventricular arrhythmias appear during administration;
- in extremely rare cases, anaphylactic shock occurs.
Forms of release of funds
Before you go to the pharmacy and select the modern analogue for the erythromycin preparation, you need to decide on the type of preparation you need. On sale you can find tablets, ointment, powder or granules for suspension and lyophilisate for injection.
In most cases, the drug is prescribed in the form of tablets to patients. But if patients need intensive care, and treatment is carried out in a hospital, then intravenous administration of the drug can be prescribed. The solution can be administered by slow injection for 3-5 minutes or drip - depending on the doctor's recommendations.
The ointment is prescribed for the treatment of pustular skin lesions, including youthful acne. It must be applied to all areas of the lesion. In case of infectious and inflammatory problems with the eyes, a special ointment is used, which must be placed behind the lower eyelid.
Powder and granules are intended for the preparation of a suspension. They are usually prescribed for children who still find it difficult to find the required dosage in tablets.
Domestic substitutes
If you don’t want to spend too much money buying erythromycin analogues, you can take pills made in Russia. In the pharmacy you can find "Erythromycin-AKOS" produced by OJSC "Synthesis" (Kurgan).
If you need to enter the drug as an injection, you can purchase erythromycin phosphate. It is made by the same Russian company Synthesis.
Also in the Russian Federation they produce Erythromycin-LECT at the Tyumen Chemical and Pharmaceutical Plant. In addition, you can find on sale the original drug Erythromycin, produced by the companies OJSC Sintez, OJSC Biosynthesis, Tatkhimpharmpreparaty, NIZHPHARM, Bryntsalov-A.
Imported analogues
Many refuse domestic preparations, even if they are prescribed the erythromycin. It is not difficult to select an import analog, because many drugs are made on the basis of this active substance.
If necessary, purchase a solution for intravenous administration, you can pay attention to the "Erythromycin Lactobionate" produced by a company from the United States. In the same country, a suspension for children "Ilozon" is made.
Erythromycin-Ratiopharm suspension powder is made in Germany, and granules for the preparation of Grunamycin syrup are also produced there.
Erythromycin-Teva, which is available in the form of tablets or powders for the preparation of suspensions, is produced in Israel. More affordable are imported drugs manufactured in India. In Russian pharmacies you can find "Erythromycin stearate" Indian production - these are tablets of 125 mg.
Outdoor facilities
Erythromycin ointment is popular
. Use this antibacterial drug as an external agent. The main active ingredient, as the name suggests, is
erythromycin. Ointment (analogues are applied in the same way as the original drug) is easy to use. The tool is smeared with a thin layer on the affected area and neatly distributed. Intensively rub it is not worth it.
Before applying the ointment to the skin, it is necessary to clean the problem area and wipe it dry. After this, squeeze a strip of the product up to 3 cm long onto the skin. The ointment must be evenly distributed. The effect occurs if it is applied for 1-2 weeks up to 4 times a day. Using this scheme, you can get rid of teenage blackheads.
You can also use a solution. It is produced under the name Erifluid. To get rid of acne, doctors recommend doing lotions or compresses with this tool. To do this, it is necessary to soak a cloth or cotton wool with a solution and apply it to the problem area for 5-15 minutes. Such compresses should be done for 2 weeks up to 3 times a day. But to increase the duration of the procedure is not worth it because of the risk of irritation.
Analogs of external means
Some people do not trust cheap domestic drugs and are looking for a new generation of erythromycin analogue. One of the well-known remedies is Zenerit. This is a lotion based on erythromycin and zinc dihydrate acetate. In a package of 2 bottles. One contains the active ingredients, and the other contains a solvent. Each of them can make a lotion on their own. It is able to suppress the reproduction of organisms that cause acne.
Means "Klindovit" is often used as an analogue of ointment, the main component of which is erythromycin. Indications for use and side effects, however, differ, because the drugs are made on the basis of different active substances. Gel “Klindovit” is used exclusively to combat acne. The course of treatment lasts more than 6 weeks.
For the treatment of boils, abscesses, acne, doctors can recommend Dalacin gel. The main active substance in it, as in the "Klindovit", is clindamycin.
The use of antibacterial suspensions
If necessary, pediatricians prescribe antibacterial drugs in the form of suspensions to children, and in many of them the main active ingredient is erythromycin. Analogs (instructions for use allows the use of such drugs even for the treatment of newborns), doctors choose at their discretion.
The specialist may prescribe a suspension of "Ilozon" for infections of the upper respiratory tract or genitourinary system. The dosage is selected depending on the weight of the small patient. Children, depending on the complexity of the situation, can be prescribed from 30 to 50 mg of the drug per kilogram of body weight per day. This dosage is prescribed for patients aged 4 months to 18 years, although adolescents, of course, are better off buying the medicine in tablet form. And newborn babies who are not yet three months old are prescribed 20-40 mg of suspension for every kilogram of their weight. In difficult cases, the dosage can be doubled.
Instead of Ilozon, suspensions of Synerit, Eomycin, Grunamycin and other products made on the basis of the active substance erythromycin can be prescribed. Analogs are taken in the same way and with the same indications as the erythromycin tablets themselves.
Price comparison
When going to the pharmacy, many want to know in advance how much they will have to spend. It will depend only on which drug the doctor prescribed. If you buy "Erythromycin" domestically produced, you can significantly save. A pack of 10 tablets of 250 mg will cost 55 rubles. A bottle of lyophilisate with a volume of 100 ml costs only 14 rubles.
Erythromycin ointment is also inexpensive. For a tube with a capacity of 15 g, you will need to pay about 26 rubles. But the Zenerit drug will cost several times more: 30 ml of the drug costs 518 rubles. Tube gel “Klindovit” costs about 289 rubles. Means "Dalacin" will cost less - for it will have to pay 112 rubles.
Erythromycin analogs in tablets made on the basis of other active substances will also be more expensive. For example, Sumamed tablets (500 mg No. 3) will cost 447 rubles. But the drug "Macropen" will cost 246 rubles. This amount will have to be paid for a pack of 16 tablets of 400 mg.
Drug Efficiency: People's Reviews
It is difficult to compare the effectiveness of taking different antibacterial agents. After all, a certain active substance is active against a number of sensitive microorganisms. But if it is necessary to treat infections caused by microorganisms that can be affected by erythromycin, then this drug is considered one of the best.
Despite the affordable price, its effectiveness remains high, as evidenced by many reviews. Of course, at the request of patients, it can be replaced by other, more expensive, means. But this, according to experts, will not accelerate the healing process.
All antibiotics doctors recommend drinking for another 2-3 days after the improvement. Erythromycin is no exception. Analogs are drunk in the same way as the original drug.
Depending on the indications and the complexity of the condition, treatment can last from 7 to 14 days. For adults, the daily dose is 1-2 g. But in severe cases, 4 g can be prescribed.
It is impossible to increase the dosage of an agent to increase effectiveness without an urgent need. After all, this can lead to negative consequences. Among them, doctors call hearing loss and the development of acute liver failure.