"Aspirin Upsa" is an anti-inflammatory non-steroidal drug that is used to relieve pain syndrome and reduce body temperature in infectious or inflammatory diseases. How effective is it? Let's figure it out.
Composition and form of release
Aspirin Upsa is produced in the form of effervescent flat white tablets (four tablets in one strip).
One tablet contains:
- 500 mg acetylsalicylic acid;
- auxiliary components: anhydrous sodium carbonate, sodium bicarbonate, povidone, anhydrous citric acid, crospovidone, anhydrous sodium citrate, natural orange flavor, aspartame.
When is the drug used?
"Aspirin Upsa" produces an antipyretic, anti-inflammatory and analgesic effect. The main advantage of the soluble form of the drug is the rapid and complete absorption of the active active ingredient and better tolerance. In addition, the drug reduces the formation of blood clots and platelet aggregation, while the antiplatelet effect persists for seven days after a single dose. What Aspirin Upsa helps from, not everyone knows.
The drug is used for:
- mild or moderate pain syndrome of various origins, including tooth and headache, joint and muscle pain, migraine, neuralgia, algodismenorea, radicular chest syndrome;
- an increase in body temperature with colds or other inflammatory and infectious pathologies.
Contraindications
According to the instructions to "Aspirin Upsa", contraindications are:
- ulcerative and erosive lesions of the gastrointestinal tract during the period of exacerbation, as well as bleeding of the stomach and intestines;
- portal hypertension;
- stratified aortic aneurysm;
- "Aspirin" asthma;
- phenylketonuria;
- lack of glucose-6-phosphate dehydrogenase;
- hemorrhagic diathesis, including thrombocytopenic purpura, telangiectasia, thrombocytopenia, hemophilia, von Willebrand disease, hypoprothrombinemia;
- excessive sensitivity to the components of "Aspirin Oops" or other anti-inflammatory non-steroidal drugs;
- lack of vitamin K;
- severe defects in the kidneys and liver.
The drug is allowed to be used only from the second trimester of pregnancy, while breastfeeding is advisable to stop breastfeeding. Also, "Aspirin Upsa" is not used to treat children under 15 years of age, since there is a possibility of Reye syndrome.
The drug should be taken carefully in the presence of pathologies such as hyperuricemia, urate nephrolithiasis, decompensated heart failure, and a history of duodenal ulcer. During the use of "Aspirin Ups", it must be borne in mind that it is capable of causing a strong attack of gout, if there is such a predisposition.
Dosage and application features
The medication is allowed for use by children whose age is more than 15 years, as well as adult patients, one tablet up to six times a day. Between receptions should be an interval of at least four hours. Before use, the tablet should be dissolved in a glass of juice or water at room temperature.
With high temperature and severe pain at the beginning of the disease, you can take two tablets at the same time, but no more than six pieces during the day, for elderly patients - no more than four. As an antipyretic agent, the drug is taken for three days, in the form of an analgesic - up to five.
If an overdose occurs, at first signs of central nervous system excitement, severe headache, vomiting, dizziness, decreased hearing acuity, nausea, increased breathing intensity may occur, which may lead to its insufficiency, visual defects, and suppression of consciousness reaching coma, and also disturbed water-electrolyte metabolism.
Caution should be exercised while taking “Aspirin Ups” with ethanol and glucocorticoid drugs, because the latter increase the effect of acetylsalicylic acid on the gastrointestinal membrane, thereby increasing the likelihood of bleeding of the intestines and stomach.
Side effects
As indicated by the instructions for use, "Aspirin Upsa" in the recommended dosage is most often well tolerated. Very rarely, when using the drug, such disorders can develop as:
- epidermal rash, Quincke's edema, bronchospasm, “aspirin triad”, epidermal rash;
- impaired renal activity;
- nosebleeds, an increase in the period of blood coagulation and gum bleeding;
- nausea, decreased appetite, intestinal and stomach bleeding, vomiting, diarrhea, pain in the epigastric region;
- leukopenia, thrombocytopenia, hyperbilirubinemia, anemia.
If undesirable effects appear, then you need to stop using the effervescent Aspirin Ups.
Special instructions for the use of the drug
The duration of treatment without medical advice cannot exceed a week when prescribed as an analgesic drug and more than three days as an antipyretic.
The use of the drug as an anti-inflammatory is currently limited in its daily dose to 5-8 grams, due to the increased likelihood of side effects from the gastrointestinal tract.
Before surgery, in order to reduce bleeding during the operation, as well as after it, you need to cancel the use of salicylates for 5-7 days and warn your doctor about it.
During prolonged treatment, a study of feces for occult blood and a general blood test should be performed.
Children are not allowed to prescribe drugs that contain acetylsalicylic acid, since with a viral infection they can increase the likelihood of Reye's syndrome. Its symptoms are prolonged vomiting, an increase in the size of the liver, as well as acute encephalopathy.
Appointment of tablets after meals, their thorough grinding, the use of tablets with buffer additives or coated with a special enteric coating, as well as the simultaneous use of drugs that neutralize the acidity of gastric juice, reduce the irritating effect on the digestive tract.
“Aspirin Upsa” is characterized by teratogenic effects; when taken in the first trimester, it becomes the cause of the splitting of the upper palate; in the third trimester, it causes inhibition of Pg synthesis, that is, it slows down labor, prematurely closes the duct of the artery in the fetus, there is hypertension in the small circle of blood circulation, and hyperplasia of the pulmonary vessels. It is excreted along with breast milk, and therefore the likelihood of developing an attack of gout in patients predisposed to this increases.
During treatment, you should refrain from using ethanol.
What else does the instruction attached to the effervescent Aspirin of Ups tell us?
Features of the interaction of the drug
Increases meteotrexate toxicity, reducing renal clearance, effects of other NSAIDs, hypoglycemic oral drugs, narcotic analgesics, heparin, reserpine, thrombolytics, indirect anticoagulants, platelet aggregation inhibitors, sulfonamides (including co-trimoxin-azolezole, including co-trimoxin-azolezole) ), antihypertensive drugs, diuretics (furosemide, spironolactone).
Ethanol, corticosteroids and ethanol-containing drugs increase the damaging effect on the mucous membrane of the intestines and stomach, increase the likelihood of gastrointestinal bleeding, and increase the plasma concentration of Li + salts, barbiturates, and digoxin. Antacids that contain Al3 + and / or Mg2 + degrade and slow down the absorption of acetylsalicylic acid. Myelotoxic type drugs increase the effects of hematoxicity.
Analogues of this drug
As analogues of "Aspirin Ups" are:
- by active component: Aspinat, Fluspirin, Aspitrin, Taspir, Aspivatrin, Asprovit, Atsbirin, Aspirin, Nektrim Fast, Acetylsalicylic acid, Upsarin Upsa , Nektrim Fast;
- according to the mechanism of influence: "Coficil-plus", "Salicylamide", "Aspagel", "Aquacitramon", "Citramon P", "Citrapak", "Alka-prim", "Aspivit", "Alka-Zelter", "AnGrikaps" , Acepar, Parkocet.
Reviews about "Aspirin Ups"
What do people think about this drug? The drug is recommended by about 92% of patients. Its advantages are: taste, good packaging, quick elimination of temperature and pain. The disadvantages of some patients consider its price and lack of effectiveness in some cases. In addition, it is considered an expensive analogue of acetylsalicylic acid.
Users note the convenience of taking tablets in a soluble effervescent form. Due to this, it is absorbed faster, therefore, the speed of the drug increases. Despite the quality of the drug, many patients do not consider it necessary to overpay for ordinary salicylic acid.
Some note that the drug does not work too fast, although it lowers the temperature. With muscle and headache, the drug does not help all patients. The instruction says that "Aspirin Oops" is indicated for pain of low intensity.