In the article, we consider the instructions for use and analogues for the Persen medication. This is a drug that is of plant origin and has a sedative and antispasmodic effect. As indicated by the instructions for use, Persen can be found on sale in the following forms:
- Tablets are biconvex round in shape, have a dark brown color.
- "Persen at night." It is a capsule preparation. It is very popular among those who suffer from insomnia. Instructions for use with "Persean night" are in every pack. Capsules have a brownish tint, inside them is a granular-like compressed mass, the color of which is greenish-brown.
- According to the instructions for use, Persen Forte is a capsule preparation. The capsules are brown-red, inside them are granules, the color of which is greenish brown.
Pharmacokinetics and pharmacodynamics
According to the instructions for use for Persen, after oral administration, the active components are absorbed into the gastrointestinal tract fully and rapidly. The time of manifestation of a pronounced sedative effect after using the drug is 30 minutes. This effect persists for up to 6 hours.
Active components are distributed everywhere in the tissues of the body; they bind to plasma proteins to a small extent. Metabolism and subsequent excretion are realized within one day.
Instructions for use with "Persen" in capsules and tablets informs that the pharmacologically medication acts as follows:
- The essential oils and acids contained in the valerian extract provide a deep sedative and antispasmodic effect on the body.
- Melissa is characterized by an antispasmodic and sedative effect. Its leaves are saturated with bitter substances, flavonoids, tannins, aldehydes, essential oils.
- The mint leaves included in the composition of Persena act antispasmodically on the smooth muscle tissue of the gastrointestinal tract. The plant component is distinguished by its inherent choleretic effect. Mint contains phenolic acid, triterpenic acid, menthol essential oils, flavonoids.
As a result of the complex effects of the components of the drug, a deep soothing effect is observed.
Structure
In accordance with the instructions for use with Persen, the main active ingredients in the composition of the tablets are extracts of peppermint, lemon balm and valerian. Moreover, each tablet contains 25, 25 and 50 mg of extracts, respectively. As auxiliary ingredients in the manufacture of tablets are used: silicon dioxide, crospovidone, corn starch, magnesium stearate, microcrystalline cellulose, talc, lactose.
Instructions for use with Persen tablets are described in great detail.
The main active components of Persen Forte and Persen Night capsules are similar extracts of herbs. The only difference from Persen tablets is the amount of their content in each capsule. So, one capsule contains 25, 25 and 125 mg of extracts of lemon balm, mint and valerian, respectively. As auxiliary ingredients are used: silicon dioxide, magnesium stearate, lactose, talc, magnesium oxide. The capsule shell is made of iron oxide, dye E110 and preservatives E102, E216, E171, E218.
Forms of release, expiration dates, conditions of dispensing from pharmacies and storage
What else can you learn from the instructions for use with Persen? The tablet preparation is packaged in blisters, each of which contains 10 pieces. Blisters are placed in cardboard packaging, the average cost of which in Russian pharmacies is at the level of 230 rubles.
According to the instructions for use, Persen Night and Persen forte are packaged in blisters, each of which can hold 10 capsules. Blisters for 1, 2 or 4 pcs. fit in a cardboard box. The average cost of the first drug is about 280 rubles, the second - 300 rubles.
The drug should be stored in a place isolated from light and moisture, the temperature should be room temperature. Persen retains its therapeutic properties for 3 years from the moment of its production. In pharmacies, the medicine is dispensed freely, for its acquisition, a prescription from the doctor is not required.
Interaction with other medicines
In the case when Persen is indicated for use simultaneously with CNS depressant drugs, it is important to adjust the dose of the first. Among these drugs: hypnotics, hypotensive drugs with a central type of exposure ("Moxonidine", "Clonidine", "Rilmenidin", "Guangfacin", "Methyldopa"), analgesic.
Indications for use
Experts recommend Persen for admission to those patients who have:
- Nervous excitability.
- Insomnia or sleep disturbances, expressed in insufficient or poor quality.
- Vegetovascular dystonia.
- The need for the prevention of psychosomatic disorders arising from stressful situations.
- The need for maintenance therapy for the withdrawal of potent sedative drugs.
- Neuroses, which are psychoemotional disorders that are reversible in nature and are due to exposure to traumatic factors.
- A high degree of irritability, which is accompanied by an increase in excitability, a tendency to the formation of negative emotions.
As indicated by the instructions for use with Persena Night, insomnia is the indication for its use.
Contraindications
Do not prescribe medication to patients if they have the following conditions:
- Individual hypersensitivity to any of the components that make up the drug.
- Bile duct dysfunction.
- Arterial hypotension or persistently high blood pressure.
- Lactase deficiency due to impaired lactose cleavage.
- Lactose intolerance, which is the inability of the body to digest and assimilate milk sugar.
- Glucose-galactose malabsorption, which is a hereditary disease, accompanied by impaired absorption in the gastrointestinal tract of monosaccharides.
Usage, dosage
When taking the drug, the patient should adhere to the schemes recommended by the doctor:
- With insomnia, you need to take up to three capsules one time half an hour before going to bed.
- With irritability and abnormal nervous excitability, the use of up to three capsules or tablets is indicated a maximum of three times a day.
In this case, the total daily dose of the medication should be no more than 12 tablets or capsules.
It is important to note that the withdrawal syndrome after stopping therapy is not formed in the patient.
This is confirmed by capsules and tablets "Persen" instructions for use and reviews.
Overdose
Overdose can occur if the patient accidentally or intentionally took a single dose of 50 capsules or 100 tablets. An overdose of the following symptoms is manifested:
- The appearance of a rash, which is localized on the skin.
- The development of peripheral puffiness as a result of excessive accumulation of fluid outside the vessels.
- The appearance of dermatitis, which is an inflammatory lesion of the epidermal layer.
- Hyperemia.
- In rare cases, bronchospasm may occur.
- If therapy is carried out for a long period, the patient may notice constipation.
If any of the signs of an overdose appears, the patient should immediately rinse the stomach and seek help from a medical facility.
Special instructions for use
A patient who is shown therapy with the use of "Persen", should take into account some features.
The use of the drug is not allowed by pregnant women, as well as those who breastfeed.
In pediatric practice, the use of the medication is allowed only in relation to children from 12 years old if Persen has a capsule form, and from 3 years old if it has a tablet form. The appointment of the drug should be done exclusively by the pediatrician, and the dosage is calculated based on the body weight of the small patient.
Caution should be exercised when taking Persena if a patient has gastroesophageal reflux disease. This limitation is due to the ability of the drug to provoke a worsening of the symptoms of the disease.
In the case when taking the drug causes an increase in symptoms, it is important for the patient to inform the attending physician about the situation.
The maximum allowable duration of the Persen therapy course is 2 months.
Persen is able to have a significant impact on the psychomotor and speed of reactions, and therefore, experts advise taking this feature of the drug into account for patients who drive vehicles and work with complex mechanisms.
Analogs
If the patient requires replacing Persena with a drug similar in composition or action, it is important to consult a doctor first. This is due to the presence in each medication of an individual series of contraindications and negative effects. Indications for use may also vary.
The most popular analogues are: motherwort extract, Antaris, Tenoten, Deprim, Sedavit, Doppelgerts Neurotic, Glycine, Cardiovalen, Valerian Forte, NovoPassit.
Reviews
The vast majority of reviews of the drug are positive. Patients note that the beginning of taking "Persen" in them was associated with a variety of stressful situations in life - on the eve of exams or problems at work and in the family, which were accompanied by the appearance of irritability, increased anxiety, severe nervous strain, and insomnia attacks. “Persen”, just a few days after the start of use, made it possible to cope with such disturbing symptoms, increase working capacity and activity, establish the process of falling asleep, and get rid of anxiety and irritability.
However, some patients leave negative reviews, claiming that the drug was useless. The reason for this inefficiency may lie in excessive nervous strain or the development of serious CNS pathologies. To exclude such unpleasant situations, it is advisable to be examined by a specialist before taking Persena.
In some cases, the negative characteristics of the drug are associated with the manifestation of impatience in patients. However, it is important to remember that the therapeutic effect of taking Persena develops gradually.
Separately, it is worth noting the positive reviews coming from neurologists and neuropathologists. These experts consider the main advantages of this medicine its plant origin, high efficiency, lack of addiction.
We reviewed the medicine "Persen" instructions for use and reviews.