Unfortunately, depressive states, mental disorders are quite common problems. In no case should they be discarded or ignored, since they require therapy, quite often medication. There is a drug that helps to cope with a number of emotional disorders, at least reviews testify to this. “Melipramin” is a medicine that is very popular in psychiatry and some other branches of medicine. So how does it affect the body?
What is included in the composition? Description of release form
There are two forms in which the drug "Melipramin" is available - tablets and a solution for internal administration. The main active substance of the drug is imipramine. Each tablet contains 25 mg of this component, as well as a number of excipients, including dimethicone, lactose monohydrate, magnesium stearate, as well as iron oxide, crospovidone and hypromellose.
As for the solution, 1 ml contains 12.5 mg of imipramine, as well as auxiliary components, in particular sodium chloride, sodium disulfite, ascorbic acid, anhydrous sodium sulfate and purified water as a base.
Description of the main properties of the drug
This tool is a pretty good antidepressant, studies and reviews testify to this. “Melipramin” in addition to this has other properties, in particular painkillers and sedatives. The drug also acts as an antidiuretic.
The active component of the drug increases the concentration of norepinephrine in the synapses, and also increases the level of serotonin in the tissues of the central nervous system. The medicine slows down ventricular conduction, as a result of which it stops the development of arrhythmia. Also, the active substance blocks histamine H2 receptors in the cells of gastric tissues, reduces acid secretion, and therefore has an antiulcer effect.
As a rule, in the beginning, the tablets cause a sedative effect, which, as the course of treatment, disappears.
List of indications for admission
There are many cases in which this medicine can help, which is confirmed by reviews. "Melipramine" is prescribed for patients who are diagnosed with the following problems:
- depressive states of endogenous origin;
- depression that occurs against the background of neurosis, psychopathy, menopause;
- astheno-depressive syndrome;
- reactive depression;
- withdrawal syndrome upon cessation of use of drugs containing cocaine;
- behavioral disorders ;
- panic disorder;
- migraine;
- alcoholic depression ;
- narcolepsy;
- neuropathies arising from diabetes mellitus;
- postherpetic neuralgia;
- severe pain of a chronic nature;
- severe headaches that cannot be stopped with other medicines;
- bulimia nervosa;
- some forms of enuresis.
The drug "Melipramin": instructions for use
As you can see, the medicine is quite strong, and therefore it is impossible to use it without permission. After a full diagnosis, only a specialist can prescribe a patient “Melipramine” medicine. Instructions for use contain only some general information.
If we are talking about the treatment of adults, the daily dose ranges from 75 to 200 mg of the active substance, depending on the condition of the patient. If the necessary therapeutic effect is absent, the dose is gradually increased to 200-300 mg. This amount of the drug is divided into 3-4 doses.
How to take Melipramin? Doctors recommend drinking pills in the morning and afternoon. If you do this in the evening, the medicine may cause insomnia. The course of treatment is from 4 to 6 weeks. In the future, supportive therapy is needed, which lasts about the same time, but the dose is gradually reduced to the patient.
What are the features of treating children with Melipramin? Tablets are also taken in the morning and at lunchtime, but the dose, of course, is different. The initial daily amount of the active component is 10 mg, after which it is gradually increased to 20 (children 6-8 years old), 25 (8-14 years old) or 50-100 mg (children over 14 years old).
Are there any contraindications?
In some cases, taking the drug may be unjustified or even dangerous. Here is a list of contraindications for therapy:
- hypersensitivity to the components of the drug;
- taking drugs - MAO inhibitors;
- acute intoxication of the body with ethyl alcohol;
- intoxication with narcotic substances;
- depression of the central nervous system;
- poisoning with sleeping pills;
- period of pregnancy and lactation;
- conduction disorders inside the ventricles of the heart;
- myocardial infarction;
- angle-closure glaucoma;
- children's age (up to 6 years).
The drug can be taken with bronchial asthma, chronic alcoholism, renal failure, heart disease, but in such cases it is necessary to carefully monitor the patient's condition. Relative contraindications also include stroke, vascular disorders, blood formation problems, impaired digestive tract motility, as well as pheochromocytoma, epilepsy, liver failure, schizophrenia, prostate hyperplasia, thyrotoxicosis and bipolar disorder.
List of possible adverse reactions
Some patients develop some side effects while taking the pills:
- from the digestive system: dryness of the mucous membrane of the oral cavity, heartburn, constipation, vomiting;
- on the part of the sensory organs: decreased clarity of vision, paresis of accommodation, glaucoma, impaired taste perception, tinnitus;
- on the part of the heart and blood vessels: tachycardia, arrhythmia, ECG changes;
- from the nervous system and psyche: depersonalization, confusion, nightmares, insomnia, psychosis, hypomanic states, difficulty urinating, hallucinations, problems with concentration, headaches, asthenia, drowsiness, disorientation, psychomotor agitation, increased depression, dizziness;
- other possible complications include hyperhidrosis, a sharp change in body weight, decreased potency, cholestatic jaundice, urticaria, metabolic disorders, and swelling of the testicles in men.
Regardless of what changes you noticed after the start of therapy, if there were disturbing symptoms, you should definitely consult a doctor.
The drug "Melipramine": analogues
This medicine is not suitable for all patients. It is worth noting that the modern market offers a fairly large selection of drugs with similar properties. Sometimes the doctor may prescribe such means as Imizin or Imprimin. These are kind of synonyms that contain the same active substance. Apo-Imipramin and Prioygan-25 also belong to the list of analogues.
Another important point for patients is the cost of Melipramine. Its price is quite affordable. A pack of 50 tablets will cost about 360-450 rubles, which is not so much, especially when compared with some analogues.
Reviews of patients and specialists about the drug
Of course, many people are interested in the opinions of doctors and people who have already managed to try the medicine on themselves. So what are the reviews about him? "Melipramine" is considered a good tool, it really helps to relieve symptoms of nervous and emotional disorders, relieve chronic pain and, in combination with other therapeutic measures, even completely eliminate the disease. Patients are also satisfied with the result, because the first effect begins to appear after several days of therapy. And naturally, one should not forget about another advantage of the Melipramin preparation: its price makes the medicine affordable.