Pariet is an antiulcer pharmacological agent that reduces the secretory function of the stomach. It accumulates in the cells of the mucous membrane, blocks the formation of hydrochloric acid. The therapeutic result depends on the selected dosage of the drug “Pariet”. The instruction indicates that taking 20 mg of the drug, patients manage to reduce the acidity of the stomach after 60 minutes. After a few hours, the maximum effect is achieved.
The secretory activity of the digestive system is fully restored 2-3 days after the end of the prescribed course of treatment. The medication does not affect the work of the respiratory, vascular and nervous systems.
Soars, instructions for the appointment
The drug is prescribed for the diagnosis of gastroesophageal reflux disease; with gastric ulcer in the acute stage; with ulcers on the mucous membranes of the digestive system that arose against the background of Zollinger-Ellison syndrome; with other ailments identified, which are characterized by pathological hypersecretion. The medication is used in complex therapy, with antibacterial pharmaceuticals, in pathological conditions of the body caused by Helicobacter pylori.
Soars, dosage instructions
Tablets are taken orally as a whole, without crushing, without chewing, before eating.
It is believed that with a single dose of Pariet - 20 mg per day, the best time for the absorption of active substances is morning. Although the activity of the main component - rabeprazole sodium is independent of the time of day.
The doctor chooses the dosage of the drug depending on the specified diagnosis. So, with an ulcer of the duodenum, 20 mg of the drug is prescribed per day. The course of treatment lasts 1 month.
With a revealed gastric ulcer, the daily single dose of the drug remains the same (20 mg), but the course of therapy is increased, and it is one and a half months.
When diagnosed with reflux esophagitis, as a rule, the treatment duration is recommended to be increased to 8 weeks.
If the purpose of the prescribed therapy is the eradication of Helicobacter pylori, then it is carried out comprehensively. In combination with antibiotics, this drug is used in an amount of 20 ml twice a day.
Soars, instruction. Side effects
Analysis of clinical studies suggests that patients tolerate the drug well. Revealed side effects are characterized by a mild effect on the human body, moreover, they quickly pass.
Some patients complained of short-term diarrhea, flatulence, constipation, nausea or dizziness, headache, asthenia, drowsiness, weakness and dryness in the oral cavity, skin rash. Very rarely, doctors noted bullous rashes in patients taking the “Pariet” medicine, sometimes erythema appeared. Adverse reaction stopped immediately after discontinuation of the drug.
Even less frequently, specialists diagnosed leukopenia, thrombocytopenia, neutropenia, and an increased level of liver transaminase activity in patients.
Contraindications for taking Pariet:
- hypersensitivity to a specific component of the drug;
- severe renal failure;
- pregnancy and lactation.
The drug "Parit" during the expectation of a child
No harmful effects of this pharmaceutical agent on the development of the fetus and the condition of the woman during pregnancy were revealed. But the studies that scientists conducted on rats give reason to argue that the substances that make up the drug penetrate the placenta. Given this, do not use the drug in pregnant women.
It is not established whether the substances that make up the tablets enter the breast milk of a nursing mother. Although scientists have discovered the drug in rat milk. Therefore, if necessary, a course of treatment for breastfeeding is better to refuse.
When prescribing Pariet tablets, their interaction with other drugs should be taken into account.
This drug inhibits the excretion of phenytoin, diazepam, indirect anticoagulants. Pariet reduces the concentration of digoxin and ketoconazole in the body.