Gastrointestinal diseases are the most common. Therefore, many pharmaceutical companies produce a large number of drugs to treat such diseases, as well as improve digestion.
Such a medicine as Panocide 40 is very popular in our country. Instructions, reviews, analogues and indications for the use of this drug are presented below.
Packaging, form, composition
The drug "Panocide 40" is available in tablet form. They include pantoprazole sodium and sodium, as well as excipients such as anhydrous sodium carbonate, mannitol E 421, dye ENS-II-041 yellow, hypromellose 5 CPS, calcium stearate, crospovidone and dye IC-S-329.
On sale, this tool can be found in blisters that are packaged in packs of cardboard.
Drug properties
What is a remedy like Panocide 40? The instruction for use claims that it is an inhibitor of the H + -K + -ATP phase. It disrupts the transfer of hydrogen ions from parietal cells into the lumen of the stomach, after which it blocks the secretion of hydrochloric acid.
With peptic ulcer associated with Helicobacter pylori, this effect on gastric secretion increases the sensitivity of microorganisms to antibiotics.
Kinetics means
After oral administration, Panocid 40 is rapidly absorbed and binds to plasma proteins by 95%.
Pantoprazole metabolism occurs in the liver. The maximum concentration of the drug in serum is observed after 2.5 hours. The therapeutic effect of the drug persists throughout the day. About 80% of the drug is excreted through the kidneys, and the rest - along with feces.
Indications
Tablets "Panocide 40", the instructions of which are described below, are prescribed for:
- duodenal ulcer
- severe and moderate reflux esophagitis;
- stomach ulcer;
- the presence of Helicobacter pylori in people with peptic ulcers that were caused by this microorganism (in complex therapy);
- Zollinger-Ellison syndrome, as well as other hypersecretory conditions.
Bans on admission
The medicine “Panocide 40”, the analogues of which are indicated below, cannot be used with hypersensitivity to pantoprazole, as well as to any components of the drug. Also, it is not used for combination therapy to eradicate Helicobacter pylori in patients with severe or moderate hepatic or renal insufficiency.
It should be noted that this tool, like other proton pump inhibitors, cannot be used together with Atazanavir during pregnancy, up to 15 years and during lactation.
Medication "Panocide 40": instructions for use
The recommended dosage of this drug for children from 15 years old and adult patients is 1 tablet once or twice a day (depending on the disease).
For people with severely impaired liver function, the indicated amount can be reduced to 1 tablet in 2 days. Such patients should be under the constant supervision of a doctor.
The course of therapy with this drug is determined only by the doctor.
Adverse reactions
Medication “Panocide 40”, the instructions for use of which were described above, can cause the following undesirable effects:
- fever, heat stroke, facial edema, abscesses, peripheral edema, malaise, generalized edema, candidiasis, asthenia, allergic reactions, chills, hernia, cyst;
- angina pectoris, cardiogram changes, chest pain, arrhythmia, hemorrhage, chest pain, myocardial ischemia, vascular disorders of the retina, tachycardia, syncope, thrombosis, thrombophlebitis;
- pancreatitis, epigastric pain, enteritis, abdominal pain, gingivitis, diarrhea, stomach ulcer, constipation, glossitis, nausea, stool disorders, vomiting, rectal hemorrhages, dry mouth, stomatitis, cardiospasm;
- diabetes mellitus, hyperlipoproteinemia, hyperglycemia, glucosuria;
- biliary pain, cholecystitis, hyperbilirubinemia, hepatitis, cholelithiasis, cholestatic jaundice;
- leukopenia, anemia, ecchymosis, thrombocytopenia, leukocytosis, hypercholesterolemia;
- dehydration, thirst, gout, increase or decrease in weight, and others.
Analogues of the drug
Now you know why patients are prescribed a drug such as Panocide 40. Instructions for use of this medication have been described above.
Experts say that there are a huge number of analogues for this drug. All of them are designed to improve the condition of the digestive tract and treat the corresponding diseases.
The most popular analogues of the drug in question include the following: “Controlok”, “Pantasan”, “Nolpaza”, “Pantokar”, “Panum”, “Pulse”, “Barol”, “Dexilant”, “Zulbeks”, “Lanzoptol”, “ Loseprazol "," Nexium "," Ozol "," Omez "," Omeprazole "," Pariet "," Ramsozol "," Ezoksium "," Emanera "and others.
It should be especially noted that all of the listed medicines have their own characteristics in use. Therefore, they can be used to treat intestinal or stomach diseases only after visiting a doctor.
Reviews of patients and doctors
What do consumers say about Panocid 40? According to them, this tool well treats diseases of the digestive tract. It is very convenient to use and has a relatively inexpensive cost. However, specialists are not always happy with the results of using this medication. They claim that this remedy is really effective, but very often causes a huge number of adverse reactions. Therefore, doctors recommend their patients to take safer drugs that do not have serious contraindications and negative consequences.