The subject of our conversation today is a drug that effectively copes with contractures and thrombosis of joints, tissue sclerosis, scars, hematomas, as well as male disease - prostatitis. This is Lidase. Instructions for use, contraindications, analogues of the drug and its average cost, side effects and effectiveness - we will discuss all this further.
The main pharmacological properties
The active active ingredient of the drug is hyaluronidase (an element obtained from bovine testes). It is designed to break down mucopolysaccharides in the body. Among the latter is the well-known hyaluronic acid, which ensures the strength and elasticity of our connective tissues.
An excess of this acid in the body will lead to the appearance of fibrosis, a decrease in the penetration of matter. Therefore, it is important to control its balance with hyaluronidase. The element makes connective tissues softer, more permeable and viscous, counteracts their compaction.
As for prostatitis, the instructions for use of "Lidase" indicate that the tool helps to cope with the disease 3-4 degrees of severity, with sclerotic changes in the tissues. The drug affects the body in this way:
- Promotes outflow of stagnant fluid.
- Helps the body quickly remove purulent formations.
- Reduces blood viscosity.
- Normalizes blood microcirculation in the vessels of the reproductive system.
- Improves the permeability of the walls of blood vessels and connective matter.
- Stops the sclerosing process.
Refers to enzyme preparations, effective in the treatment of a number of diseases associated with tissue hyperplasia.
Forms of drug release
"Lidase" in pharmacies can be presented in the following varieties:
- Powder form. Designed for both injection and external (topical use). These are ampoules or vials. Standardly in one container contains 64 PIECES of active substance.
- Candles
Each of the produced forms is accompanied by instructions for the use of "Lidase". The drug in the form of ampoules for injection is available on prescription - in the document it will be indicated Lydasum (pro injectionibus).
Alternative remedies
Now we will analyze the analogues of "Lidase" (instructions for use, reviews - later in the article). The following effects are considered to be similar in effect:
- Lidaza-M
- "Hyaluronidase."
- "Ronidase."
In all of these drugs, hyaluronidase will be the active component, as in this one.
A significant drawback of Lidase is the daily administration of the drug. This is due to the fact that the enzyme substance is unstable in the human body, is rapidly excreted. Therefore, scientists have developed a more powerful analogue of Lidase - the drug Longidaza.
What is the advantage? It is combined with hyaluronidase and polyoxidonium, which is a powerful immunomodulator. "Longidaza" is a more stable and powerful physiologically active complex. It also shows excellent results in the treatment of pathologies and diseases caused by hyperplasia of matter.
Cost of medicine
Instructions for use, reviews of "Lidase" will be presented in the material below. Now we will analyze another important issue - the cost of the drug. It depends on the specific pharmacological manufacturer.
Average prices are as follows:
- Drugs in ampoules - 200-300 rubles per package.
- Drugs in bottles - up to 600 rubles apiece.
If a tool for preparing a solution is immediately applied to the powder form, then the cost of such a complex, respectively, will be higher.
Injection
Consider the instructions for the use of "Lidase" in injections. The drug is administered subcutaneously, intravenously or intramuscularly - as directed by your doctor.
How to breed "Lidase" for injections? Instructions for use prescribe the following:
- Powdered drug "Lidase" from one ampoule is diluted with 1 ml of saline.
- The powdered drug "Lidase" can also be diluted with a solution of novocaine 0.5% concentration.
How to dilute "Lidazu", the instructions for use are described in detail. Typically, in one package will be 10 bottles for injection.
For example, in the treatment of prostatitis, one course is 10-20 injections administered intramuscularly. In severe stages of the disease, dosage, frequency, duration of treatment can be increased.
For the purpose of prevention, the course of injection of Lidase injections lasts two weeks.
Candle application
Now, consider the instructions for using Lidase in candles. This form can be shown with benign prostatic hyperplasia, prostatitis. In most cases, it is prescribed as an additional tool in the main treatment.
The main advantages of suppositories (another name for rectal suppositories) are the rapid absorption of the active substance by the tissues, the provision of bactericidal and anti-inflammatory effects. In addition, rectal suppositories contribute to the rapid elimination of toxins from the body. What is important, without passing through the liver and kidneys, the medicine does not affect their functionality.
Instructions for use "Lidase" indicates that the duration of the course of treatment with suppositories is determined only by the attending physician. Usually it is 10-20 days, in advanced cases - about a month. If the patient uses the drug for a long time, then you need to take breaks.
Before using suppositories, you need to cleanse the intestines with an herbal enema. A candle is inserted into the anus, lying on its side. It is recommended to stay in this position for another 30-40 minutes after that for the fastest absorption of the active ingredient.
Reviews on the use of candles
Reviews about "Lidaz" (instructions for the use of candles were discussed above) of this form of release are as follows:
- The drug helps to quickly reduce swelling - this is noticeable both visually and during palpation. The effect is noticed by patients even after the first use of the drug.
- Reduction of pain during urination until their complete disappearance. This is noted by patients after 3-5 procedures with suppositories.
- The prostate returns to normal size.
- Restoration of the reproductive function of the prostate gland.
The use of solution in physiotherapy
Along with suppositories and injections, the solution of the drug is widely used in electrophoresis procedures. It is aimed at smoothing scars, resorption of many infiltrates.
Physiotherapy lasts about 15-20 minutes. On average, a specialist prescribes from ten to twenty such sessions to a patient. Courses can be repeated with a frequency of no more than 2-3 times a year.
The use of ointments with "Lidase"
The active component of Lidase is also included in a series of ointments based on the topography of many manufacturers. The value of this tool is that it contributes to the rapid regeneration of the skin, it is effective for hematomas, it allows you to dissolve scars.
In some cases, it is made directly according to the prescription of the attending physician in a special production pharmacy. The standard composition of the drug is as follows:
- Tizol - 10 g.
- "Lidase" - 128 UE.
In addition, you can prepare such a useful ointment yourself at home:
- Take 2 Lidase vials from a pharmacy filled with powder.
- Carefully open each of them, add two drops of ordinary boiled water.
- Then the resulting mixture must be dissolved in 10 g of tisol.
After the tool has become a homogeneous mass, it can be used for its intended purpose. Such a self-made drug is stored for up to 2 years.
The most successful use of the product is with the use of a bandage. Ointment is impregnated with sterile gauze, previously folded in several layers. Then the matter is attached to the affected area. For fixation, you can use a bandage or adhesive plaster.
The frequency of use of such applications is every day. The duration of treatment is from 2 weeks to 2 months. At the same time, it is important to take breaks of three to four days between every 14-15 sessions with dressings.
Application in gynecology
Used "Lidase" in the gynecological field. Here it is effective in solution with dimexide. Tampons are impregnated with this drug. Dimexide helps the active substance more likely to penetrate the tissues.
A similar treatment with tampons with "Lidase" is prescribed to relieve edema, remove purulent contents from the female genital organs.
Application in cosmetology
In this area, the drug is used both externally and in the form of subcutaneous injections. What is beneficial for such an application? Its main advantages are as follows:
- Reduction of swelling of the skin.
- Resorption of hematomas.
- Recovery in tissues of normal lymph flow.
Injections with Lidase, among other things, are a real salvation for patients whose operations, facial rejuvenation procedures had negative consequences, were unsuccessful. The drug helps to even out the low-quality effect, to return the aesthetic appeal of the appearance.
Side effects
Unpleasant moments manifest themselves only with an overdose of the drug. The following stand out here:
- General malaise.
- Vomiting
- Nausea.
- Dizziness.
- Various allergic reactions.
- Tachycardia.
- When using candles - swelling in the location of their use.
Contraindications
Analogs, instructions for the use of "Lidase" we reviewed above. Now we turn to a list of contraindications for the use of this enzyme preparation based on hyaluronidase:
- Pregnancy.
- Infectious diseases.
- Hemorrhages in the recent past.
- Hypersensitivity or individual intolerance to both the active active substance and one of the auxiliary components.
- Renal failure.
- Pregnancy.
- If the tool is used for inhalation, then a separate contraindication in this case will be tuberculosis.
Is taking alcohol a prohibition on the use of Lidase? Instructions for use (in gynecology and other medical fields) do not give a definite answer to this question. However, it must be remembered that the use of alcohol will adversely affect the treatment of any drug.
To summarize. Lidase is a well-known enzyme preparation that has a number of analogues. The popularity of the drug is ensured not only by its effectiveness (this is also confirmed by patient reviews), but also by its wide scope. "Lidase" is indispensable in the treatment of prostatitis, various forms of tissue hyperplasia. It is used in dermatology (ointment), cosmetology (injection), female gynecology, during physiotherapy procedures.