Why is Azix-derm needed? Reviews and instructions for using this tool will be presented in this article. From it you will learn about the composition of the medication, its analogues and more.
The form, packaging and composition of the medical product
In what form can I get a drug like Azix-derm? Instructions, reviews of experts indicate that this drug goes on sale in the form of a cream. Its active substance is azelaic acid.
You can buy such a medicine in plastic tubes of 30 g, which are packed in packs of cardboard.
Pharmacological properties of the external drug
How does the Azix-derm medication work? The instruction says that this drug has a moderate cytostatic effect. This happens due to the inhibition of cell protein synthesis, and is manifested in the normalization of keratinization processes in the walls of the follicles of the sebaceous glands.
What are the properties of the Azix-derm cream? The doctors' reviews inform patients that it has an antimicrobial effect, which is primarily aimed at Staphylococcus epidermidis and Propionibacterium acnes.
The drug is used as an anti-inflammatory agent that acts on the surface of the skin and on the sebaceous glands. It reduces the metabolism of neutrophilic granulocytes, as well as the production of free radical forms of oxygen, that is, important factors in maintaining inflammatory reactions.
With prolonged use of the cream, the resistance of microorganisms does not form. The active substance of the drug dose-dependently inhibits the viability and growth of abnormal melanocytes. The high effect of the drug (with hyperpigmentation) is due to the suppression of respiration of cells of abnormal melanocytes, as well as the inhibition of DNA synthesis.
With rosacea, the therapeutic effect of the drug is associated with a decrease in the formation of anti-inflammatory reaction radicals of oxygen.
Pharmacokinetic features of the drug
After using the cream, it immediately penetrates the dermis and epidermis. After applying 1 g of azelaic acid (i.e. 5 g of the drug) to the skin, approximately 4% of this dose is absorbed into the systemic circulation. A small part of it is excreted through the kidneys in an unchanged form. Also, the medication comes in the form of dicarboxylic acids (C7 and C5), which are formed from azelaic acid during beta oxidation.
Indications for use of the cream
For what purposes can the medicine “Aziks-derm” be prescribed? The instruction says that such a tool is highly effective for common acne, pathological hyperpigmentation, including melasma, as well as seborrheic dermatitis.
Use this cream with such indications should only be prescribed by a doctor.
Contraindications
Does Acix-derm cream have contraindications for acne? Reviews of experts say that there are not so many prohibitions on the use of this tool. Among them, one should especially highlight the increased sensitivity of a person to the components of the drug, as well as adolescence up to 12 years.
Cream "Aziks-derm": instructions for use
How should I use the drug in question? The cream is applied only externally (on the skin).
The maximum duration of treatment with this agent depends on the characteristics of the patient’s body, the individual picture of the existing disease, as well as the severity of the signs. Therefore, the use of such a drug should only be prescribed by a specialist.
For adults, as well as children over 12 years of age, the medication is uniformly applied (in a thin layer) twice a day (in the morning and before bedtime). In this case, the skin is pre-cleaned with hypoallergenic agents or ordinary water.
Before applying the treatment cream, areas of the skin of the neck, face, or upper chest that are affected by acne must be dried.
At what dose is Azix-derm used? Reviews of experts inform patients that for the whole face it is enough to apply only 2.5 cm of a column of cream.
The medication must be used regularly throughout the course of therapy. Moreover, its duration depends on the severity of the disease.
The minimum duration of melasma therapy is about 3 months. In the process of treating this disease, you should definitely use sunscreens (such as UV A and UV B). This is done in order to prevent exacerbation of the disease or re-pigmentation of the skin under the influence of direct sunlight.
In people with acne vulgaris, a noticeable improvement is observed after about 4-5 weeks. To achieve the best results, the use of the medication should be continued for several months.
Breastfeeding Period and Pregnancy
Is it possible to use Azix-derm cream during gestation? The composition of this medication is such that during pregnancy it is used only if the intended benefit for the expectant mother significantly exceeds the probable risk for the baby. It should also be noted that it is necessary to avoid applying the drug to the area of the mammary glands during breastfeeding. Otherwise, this can lead to serious consequences.
Side effects after using the drug
Are there any undesirable effects after using the Azix-derm medication? Reviews of patients and specialists say that often such a drug causes irritation from the skin, as well as hyperemia, erythema, burning sensation, itching and peeling. As a rule, such effects are observed at the very beginning of therapy. Usually they pass independently in the process of further treatment.
In addition to the above, allergic reactions (for example, a rash) may occur in patients. Also, after applying the drug to the skin of the face very often there is a feeling of tingling and burning sensation. However, it should be noted that such sensations disappear on their own within ¼ hour.
Special recommendations for the use of cream
What should the patient know before using the Azix-derm medication? Reviews of doctors say that it is necessary to avoid getting the product in the eyes and on the mucous membranes of the mouth and nose. If such an effect did occur, then immediately rinse the listed parts of the face with a large volume of warm water.
In case of pronounced irritation of the skin in the first days of treatment, Azix-Derm Cream is recommended to be used once a day or to reduce the amount of the drug used. It is also possible to cancel the medication for a short time.
After the disappearance of all signs of irritation of the skin, it is necessary to resume regular use of the drug in the dosage recommended by the doctor.
According to experts, dermal melasma is insensitive to therapy with the drug in question. To conduct differential diagnosis, a Wood lamp is used.
Cream "Aziks-derm" is allowed to be used in combination with other methods of treating acne and other skin problems. In this case, it is possible to easily adjust the dosage regimen of all other drugs.
The drug "Aziks-derm" is not able to exert any effect on the ability of a person to drive vehicles, as well as work with other complex mechanisms.
Analogs of an external agent and its price
What can replace Aziks-derm? This drug has several analogues. The most famous are the Azelik external gel, as well as medications such as Skinoren and Skinclir. These funds can be purchased at any pharmacy. However, it should be noted that Aziks-derm can be replaced only after consultation with a specialist.
How much is the drug in question? Its price is quite high. For 30 g of 20% cream you will have to give about 650 Russian rubles. It should also be noted that analogues of this medication are no less expensive. The same amount of Azelik gel can be bought for 670-680 rubles, while Skinoren and Skinklir gel can be bought for 850 and 830 rubles, respectively.
Reviews of patients about the external drug
What do they say about an acne remedy like Azix-derm? Patients leave only positive reviews about him. They argue that such a medication quite effectively fights against acne, as well as other skin problems. However, this happens only if the drug was used strictly according to the indications and as prescribed by a narrow specialist (i.e. a dermatologist). It should also be noted that the therapeutic effectiveness of this agent appears only after prolonged and regular use of the cream.
It is impossible not to say that this drug is rare, but negative reviews still occur. Some patients using an acne remedy did not report any result. Experts explain this fact by the fact that each person is individual, and the same drug can affect people in different ways. By the way, among the negative reviews can be noted those that say that the cream "Aziks-derm" is a very expensive tool.