The antiviral drug Ergoferon is an immunomodulatory homeopathic preparation of the complete type. It has anti-inflammatory, antihistamine, antiviral activity. The price of the drug "Ergoferon" (composition of the drug, analogues are given in the article) corresponds to the level of quality.
Clinical and pharmacological properties
The antiviral drug Ergoferon is considered an antihistamine. The composition of the drug includes the following active substances:
- affinity purified antibodies to CD4 (non appropriated);
- affinity purified antibodies to human gamma interferon (non appropriated);
- affinity purified anti-histamine antibodies (non appropriated).
Composition, release options and packaging of the drug
The antiviral drug Ergoferon is available in the form of lozenges. The color of the medicine is white (almost white), the tablet form is flat-cylindrical, with a chamfer and a risk. On the flat side with a risk, the words MATERIA MEDICA are fixed, on the other side with the bevel written ERGOFERON.
The active substances in one tablet of the drug are contained in the following volumes:
- Affinity purified antibodies to CD4 - 0.006 grams.
- Affinity purified antibodies to human gamma interferon - 0.006 grams.
- Affinity purified antibodies to histamine - 0.006 grams.
All of these substances are mixed in the form of three hydroalcoholic active substance dilutions. The mixing proportions are as follows: 100 12 , 100 30 , 100 50 times.
In addition to the main substances, the drug contains auxiliary elements: lactose monohydrate (0.267 g), microcrystalline cellulose (0.03 g), magnesium stearate (0.003 g).
The antiviral agent is available in cardboard packs of different volumes of twenty pieces. Contour cell packages are available in one, two, five cells in each box.
The effect of the drug is a pharmacological type
The antiviral drug Ergoferon has a large spectrum of pharmacological activity. It includes immunomodulatory, antiviral, anti-inflammatory and antihistamine action directions.
It has been clinically and experimentally proven that the components of this drug are effective for use in the event of a viral infection: group A or B flu, acute respiratory viral infections (caused by adenoviruses, parainfluenza, coronaviruses, respiratory syncytial viruses, etc.).
Also, this drug is effective for herpesvirus infections (labial, herpes zoster, genital herpes, ophthalmic herpes, chickenpox, infectious mononucleosis), viral-type acute intestinal infections (caused by caliciviruses, coronaviruses, rotaviruses, enteroviruses).
In addition to the action of the drug “Ergoferon” in case of rotovirus and other diseases, the antiviral agent helps with meningococcal and enteroviral meningitis, hemorrhagic fever with renal syndrome and tick-borne encephalitis.
The indicated preparation is widely used in the complex therapeutic fight against bacterial infections (whooping cough, pseudotuberculosis, yersiniosis, various types of pneumonia). Also, the drug is often used to prevent bacterial complications as a consequence of a viral infection and prevent the development of superinfection.
The drug can be prescribed in the pre-vaccination and post-vaccination periods, which significantly increases the degree of vaccination efficiency, provides non-specific type of prophylaxis against influenza and acute respiratory viral infections during the formation of immunity of the post-vaccination nature.
According to the instructions for use, “Ergoferon” for adults and children is used as an effective prophylactic for the treatment of non-influenza-type SARS, to prevent the development of intercurrent diseases after vaccination.
The components that are included in the drug have a single mechanism of action in the form of increasing the activity of the functional type of receptors for interferon gamma (IFN γ), CD4 receptors and histamine. All this is accompanied by a pronounced effect of an immunotropic nature.
Experimental methods have been shown to increase the expression of IFN α / β, IFN γ and conjugated interleukins IL-4, IL-2, IL-10 and others) in connection with the interaction of antibodies and interferon gamma. In addition, this effect improves the interaction of the ligand-receptor type against IFN, restores the status of a cytokine character, normalizes the functionality, activity and concentration of naturally-occurring antibodies to IFN γ, which are important factors for the development of antiviral natural tolerance of the human body.
In addition, the interaction of the elements that make up the drug stimulates biological interferon-dependent processes (generalized expression of antigens of the main complex of the first and second types of histocompatibility, as well as Fc receptors, activation of monocytes, stimulation of the functional work of NK cells, regulation of immunoglobulin synthesis after activation of mixed Th2 and Th1).
The combined use of all components of the complex type in one drug significantly enhances the antiviral activity of each element of the drug.
Pharmacokinetic properties
According to the instructions for use, Ergoferon (adults and children can take it) has specific pharmacokinetic properties. The peculiarities are that the degree of sensitivity of modern chemical-physical analytical methods (gas-liquid chromatography, high-performance liquid chromatography, chromatography-mass spectrometry) does not make it possible to fully evaluate the content of active components in a drug in tissues, organs, and biological type fluids.
In connection with these problems from a technical point of view, it is impossible to study the pharmacokinetic properties of the drug.
Indications and contraindications
The instructions for use of Ergoferon (it is often prescribed for adults) that the drug is used in the following cases:
- treatment and prevention of group B and A flu;
- treatment and prevention of diseases associated with acute respiratory viral infections caused by adenovirus, parainfluenza, coronavirus, respiratory syncytial virus;
- treatment and prevention of herpes virus infections (ophthalmic herpes, labial and genital herpes, chickenpox, infectious mononucleosis, herpes zoster);
- treatment and prevention of acute intestinal infections with viral etymology that are caused by one of the causative agents of the disease (calicivirus, coronavirus, adenovirus, enterovirus, rotavirus);
- treatment and prevention of meningococcal and enteroviral meningitis, hemorrhagic fever with renal syndrome, encephalitis (tick-borne);
- the use in therapy of a complex type associated with bacterial infections (pseudotuberculosis, whooping cough, yersiniosis, pneumonia with various etiologies, including those caused by atypical pathogens);
- prevention of bacterial complications associated with viral infections and the prevention of superinfection.
The ban on the use of the drug alone. Contraindications for Ergoferon - individual increased sensitivity of the human body to the components of the drug.
Dosage of drug
Having considered why Ergoferon helps, you should study the features of taking the drug. The drug must be taken inside, separately from the meal. To achieve maximum effect, the tablet should be kept under the tongue (or just lying), do not swallow, so that it completely dissolves.
There are features of how to give Ergoferon to children. If the children are prescribed a drug from six months to three years old, it must be dissolved in a small amount of water (boiled). It is important that the liquid has room temperature. Dissolve the tablet in a tablespoon of water.
The treatment regimen for the drug is as follows. The first day of taking the medicine involves consuming eight tablets: one every thirty minutes in the first two hours. The total number of tablets in the first period is five.
According to the testimony of Ergoferon, after the end of the two-hour period in the first twenty-four hours, one tablet is taken every three hours, at regular intervals. On the second and subsequent days, the medication is reduced to three tablets per day until complete cure.
The use of the drug for preventive purposes
Unlike the treatment process, there are features of how to drink “Ergoferon” for the prevention of viral infectious diseases. In this case, the number of tablets taken is reduced to one or two per day.
The duration of the course of prevention recommended by doctors is from one month to six months. The specific period of taking the drug is determined individually.
If necessary, you can use the drug along with other antiviral and symptomatic agents.
Side effects, overdose and interaction with other drugs
Having studied in detail what Ergoferon helps from, it is necessary to consider the side effects of the drug.
If an overdose is accidentally allowed when taking the drug, dyspeptic phenomena may occur due to excipients that are part of the treatment.
With regard to drug interactions, it should be noted that to date, there have been no cases of drug incompatibility with other therapeutic agents.
Separately, it should be noted the compatibility features of Ergoferon and alcohol. Reviews of doctors say that taking the medication in question with alcohol together is not recommended. Because of this, the patient’s body can be harmed, and the effectiveness of the treatment can be reduced to zero.
In this regard, after taking the drug, it is recommended to maintain a twenty-four hour interval. If the patient drank any alcoholic drink, at least ten to fifteen hours should pass before taking the medicine.
special instructions
Since the drug contains lactose monohydrate, it should not be prescribed to people who are diagnosed with congenital galactosemia, galactose or glucose malabsorption syndrome, or congenital lactase deficiency.
Regarding the impact on the ability to drive vehicles and various mechanisms, it should be noted that the drug "Ergoferon" does not have such negative properties.
It should be noted that the safety of using the treatment during pregnancy and lactation has not been studied. In this regard, it is necessary to be guided by the rule that the benefit for the mother should exceed the potential harm for the baby.
Terms of sale of funds in pharmacies, storage, reviews
The drug “Ergoferon” for the treatment of colds is available in pharmacies without a prescription. The shelf life of the drug is not more than three years. Keep the packaging in a place inaccessible to small children, protected from direct sunlight, storage temperature - not more than twenty-five degrees. After the expiration date of the drug has expired, it is forbidden to use it.
Reviews about the drug in most cases are positive. In particular, they note the effectiveness of the drug for children with laryngitis, acute respiratory viral infections, tracheitis, etc.
They are especially positive for this drug of a therapeutic type due to the fact that it does not belong to the group of homeopathic remedies. The convenience of taking the medicine is also noted due to the ability to easily reduce the dosage by breaking the tablets in half.
A lot of positive reviews relate to the opportunity to purchase the drug in any pharmacy without a prescription, as well as the safety of the medicine for young children.
Some patients spoke negatively about the remedy, stating not only its inefficiency, but also that the symptoms after taking the drug worsened.
Also on the sites you can find many negative statements regarding the price of the medicine. This is due to the fact that the dosage of the drug requires taking a large number of tablets during the treatment period. Therefore, often one small package is enough for only one course.
Many reviews relate to the analogues of Ergoferon. There are no medicines completely identical to the one in pharmacies. In this case, the pharmacists themselves, treating doctors, patients consider the following drugs as analogues: Anaferon, Otsilokoktsinum, Viferon, Kagocel. The degree of effectiveness of each of these drugs is different, but the overall effect is almost the same.
The antiviral drug Ergoferon is intended for the treatment and prevention of a wide range of diseases associated with the effects of bacteria on the human body. The achievement of the highest efficiency from taking the drug can be achieved with the correct use of tablets and observing the dosage and timing of administration. It is best to purchase a large package of the drug.