Nonsteroidal anti-inflammatory drugs include a whole group of drugs. Their principle of action is based on blocking a certain type of enzyme that causes pathological reactions. The main effect of using these drugs is their ability to reduce inflammation, relieve fever and anesthetize. NSAIDs are indicated to lower the temperature and decrease blood coagulation. In addition, they are able to relieve headache, joint and muscle pain.
Nonsteroidal anti-inflammatory drugs have unwanted side effects. When taking these medications, exacerbation of ulcerative processes in the duodenum and stomach is possible. In addition, the occurrence of allergies is likely.
Non-steroidal anti-inflammatory drugs do not belong to steroid hormones. Inflammation, pain, and fever are symptoms of many ailments. All these indicators are controlled by biologically active substances in the body called prostaglandins. This group of enzymes is produced in tissues that are the focus of the disease. When these substances act on nerve fibers and blood vessels, puffiness, pain and redness occur. Prostaglandins activate the brain center, which regulates body temperature and, thereby, provoke its increase.
Nonsteroidal anti-inflammatory drugs inhibit the formation of prostaglandins. As a result of this, the pain passes, the temperature normalizes and the inflammation stops. Anti-inflammatory drugs also increase blood flow. This ability is widely used in the treatment of various diseases of the heart muscle.
Nonsteroidal anti-inflammatory drugs find their application in the following cases:
- To reduce body temperature, both adults and children, resulting from various ailments.
- To reduce the inflammatory processes caused by diseases of the osteoarticular system.
- For pain relief during migraines, as well as in the treatment of gynecological diseases and renal colic.
- To reduce blood viscosity with ischemia, heart attack and stroke.
Representatives of this group of drugs are: Acetylsalicylic acid, Diclofenac, Indomethacin, Ibuprofen and many others. For outdoor use, fastum is used.
Non-steroidal anti-inflammatory drugs of a new generation, have the properties not to cause ulceration in the stomach. This makes it possible to increase doses to cure the disease more quickly.
Anti-inflammatory drugs in dentistry are used for toothache, myalgia of the maxillofacial areas, arthritis of the temporal and maxillary joints, as well as lupus erythematosus. The greatest analgesic effect is exerted by trometamine ketorolac, which is only three times weaker than morphine. However, prolonged use of this drug is not recommended, due to undesirable effects on the stomach. When prescribing high dosages of aspirin, it is also necessary to take into account the likelihood of internal bleeding and toxic effects on the auditory nerve. With local anesthesia in dentistry, benzidamine and mafenamine sodium salt are used.
Some plants also have non-steroidal anti-inflammatory properties. Willow bark, tea and jam from raspberry branches have antimicrobial and antipyretic effects. When used locally, calendula and chamomile infusions have a strong antiviral effect. Based on natural plant materials, pharmacological preparations and homeopathic remedies are produced, such as Tincture of Cinquefoil , Revma-gel and others.