Quite a lot of interest among the general public is caused by the instructions of doctors to Mildronate, reviews about taking this drug. The tool was widely publicized due to a number of sports scandals, as it was equated to doping. However, if its use in a sports environment is limited, then ordinary people can resort to this tool, however, only with the appointment of a doctor. Reviews of the instructions for use of Mildronate analogues show that this tool is preferable to many alternative options. What are the features of the medication?
What is this about?
As can be seen from the reviews, the instructions for the tablets "Mildronate", this drug is designed to improve the functioning of the cardiovascular system. Under the influence of the active compound, the oxygen concentration in human blood rises. This reduces the risk of coronary disease. As can be seen from the reviews, instructions for injections "Mildronate", the drug is necessary for the treatment and prevention of life-threatening heart diseases. The tool is included in the list of essential drugs.
On sale, "Mildronate" is present in the form of ampoules, tablets and capsules. Ampoules contain a special liquid that is completely ready for use. As can be seen from the reviews about injections intravenously, Mildronate (the instructions for use are always enclosed by the manufacturer in the package for the medication) in this form has the fastest and most powerful effect. If a person cannot use the drug in the form of injections, an alternative is tablets or capsules enclosed in a shell of gelatin.
Use wisely
A large selection of Mildronate forms in pharmacies currently allows you to choose the best option for yourself, taking into account the dosage recommended by your doctor. As can be seen from the injections reviews, the instructions for the use of Mildronate, it is undesirable to make several injections in a row, therefore, at a high dosage, capsules manufactured with an active ingredient content of 250, 500 mg become the best option. Tablets, in turn, are convenient with the ability to divide a single dose into several doses. It must be remembered that the injection solution must be used completely at a time, but the tablet can be divided into several portions.
In addition to the active component of the capsule, tablets contain additional specific substances. If it is known that the patient has intolerance to any compound used in the pharmaceutical industry, it is necessary to carefully read the composition before proceeding with treatment. As can be seen from the reviews of doctors about the instructions for the use of Mildronate, the manufacturer completely indicates the composition (under current law it is not necessary to indicate all components without exception). Thanks to this, the use of the medication is quite safe. Mildronate contains starch, calcium stearate, and silicon in the form of dioxide.
One hundred percent efficiency
As can be seen from the reviews of cardiologists, the instructions for use, "Mildronate" lowers the concentration of carnitine in the blood, so carboxylic acids with one base from the aliphatic group cannot go down through cell membranes. Experts note that with a high level of effectiveness, this drug has minimal side effects, so you can resort to it when treating a wide population.
With the accumulation of the active active substance, aliphatic acids of carbon in the tissues of the body are fixed in a markedly lower amount than before the start of the therapeutic course. And these compounds, as doctors managed to establish, negatively affect the well-being of a person: there is a feeling of loss of strength.
Application features
Under the influence of coronary heart disease, heart tissues change their structure, suffering greatly from a lack of oxygen. As can be seen from the instructions, reviews by cardiologists about Mildronate, the active components of the drug positively affect the patient's condition. The oxygen supply to the cells is normalized, which allows the tissues to regenerate normally. Also, the reviews of cardiologists, the instruction of "Mildronate" clearly explain that under the influence of the medication, the mechanics of the oxidative process affecting glucose contained in the human body change. The transport of adenosine triphosphate is inhibited. When creating the drug, the fact was also taken into account that, when the concentration of carnitine in the living tissues is reduced, the production of the vasodilator u-butyrobetaine is activated.
As can be seen from the published for tablets 500, 250 mg instructions for the use of Mildronate (reviews of this drug indicate its high effectiveness and the rapid onset of the primary effect during therapy under medical supervision), the drug is rapidly absorbed from the digestive tract. Bioavailability is about 78%. The active compound enters the bloodstream, and the highest level of concentration is observed after several hours from the date of initial use. The instructions for the use of Mildronate tablets (reviews about them are no worse than about injections) indicate that as the active compound is processed, glucose, succinate, 3-hydroxypropion acid are produced in the blood. All these components are completely safe for humans and do not poison living tissue.
Important aspects
As can be seen from the instructions for use, Mildronate (reviews show that the drug is effective) is excreted from the body in an average of five hours. Much depends on the characteristics of a particular patient, the activity of the functioning of the kidneys and urinary system.
As can be seen from the instructions for use of Mildronate (reviews indicate that this option is really preferable), injections when ingested are more effective, since the active substance is absorbed completely. Intramuscular administration has several advantages, including reducing the likelihood of side effects, so doctors usually recommend resorting to this option. Excretion of metabolites is carried out by the kidneys.
Mildronate: heart problems are a thing of the past
As can be seen from the reviews, instructions, "Mildronate" allows you to get rid of a number of troubles associated with insufficient functioning of the cardiovascular system. The medication is suitable for patients aged 16 years and older. The manufacturer recommends using it for ischemia and other cardiac pathologies, with problems in the functioning of peripheral arteries. As can be seen from the instructions, reviews, "Mildronat" improves the condition of those faced with increased loads, people stress, and is also effective in case of a breakdown.
"Mildronate" is often used as one of the elements of the complex therapy of some types of encephalopathy. The drug has a good effect during the rehabilitation period after surgery. As can be seen from the instructions, reviews, Mildronate stimulates regenerative processes in the body, and also improves the general condition of patients. In addition, the medication gives a positive effect in heart failure in a chronic form, heart attacks and asthma. As can be seen from the instructions of Mildronate (reviews confirm this), the drug is applicable for stroke and a number of mental disorders provoked by alcohol dependence.
Special cases
At the moment, there is no official information about side effects when taking Mildronate during pregnancy. In the general case, doctors recommend not resorting to this medication in an “interesting” period, but in a particular situation, after weighing all the risks and possible benefits for the mother, the doctor may advise you to undergo treatment. In this case, the expectant mother should be clearly aware of all the risks associated with treatment. Until now, the effect of Mildronate components on the fetus has not been fully studied, which provokes unforeseen dangers - it is likely that the development of the embryo will be abnormal.
There is no exact data on whether the active components of the drug are able to penetrate into breast milk. When undergoing the therapeutic course of Mildronate, it is recommended to temporarily stop breastfeeding. An alternative is to abandon this medication in favor of another, more appropriate for a nursing mother.
Teamwork
It is known that the active substance on the basis of which Mildronate is built can interact with a number of compounds used in the pharmaceutical industry. At the same time, situations of conflict interaction have not been recorded. An exception is therapy with the use of vasodilatating agents: they are categorically not combined with Mildronate, since the risk of low blood pressure and cardiac arrhythmias is growing.
As can be seen from the medical statistics, Mildronate is often prescribed for sleep problems. The effect is observed both with insomnia and with excessively painfully vivid dreams. Mildronate is effective against headaches and dizziness, eliminates tinnitus. Often this medication is used with a predisposition to fainting. Mildronate is widely distributed among athletes, as it activates the absorption of glucose. At the same time, you need to remember that the tool is included in the prohibited list, is equated to doping, so you can not resort to it in the career of a professional athlete.
Mildronate and Sports
There is a stereotype based on the inclusion of Mildronate in the doping list: the use of this medication can achieve significantly better results than are available to an athlete without chemical support. Such a misconception is erroneous: studies show that the effect on athletic performance is relatively low if you use Mildronate within a reasonable and controlled by a doctor. The tool strengthens the body, helps to better cope with stress. However, with overly active use, side effects may occur. Also, the use of Mildronate can affect the results of competitions, if very large doses are used, which is associated with a high health hazard.
As shown by many years of research, with the reasonable, proper use of Mildronate under the supervision of a trainer, a doctor specializing in working with athletes, it is possible to achieve increased endurance. However, the positive effect is not only on the physical component: the ability to successfully transfer intellectual loads also increases. The correct, correct use of the medication allows you to normalize and activate the work of the heart muscle, but fatigue decreases. During rest under the influence of Mildronate components, the body is better, more fully restored. If you need constant physical training, the Mildronate technique allows you to increase the level of exercise that is acceptable for an athlete.
Truth and myths
Among lay people there is an erroneous belief that the use of Mildronate can provoke an increase in muscle mass. The opinion is completely wrong, this medication has no effect on muscle volumes. Athletes take Mildronate only as a means to restore strength, strengthen the body and increase resistance to stress. Proper use of the medication helps prevent overwork, including chronic.
But the statement that “Mildronate” helps the tissues regenerate is absolutely correct. Indeed, when taking this drug, the cells recover faster, as the flow of oxygen to the tissues is activated. Metabolism also becomes more active.
Features of the drug
It is believed that taking Mildronate may affect liver activity, which over time can even provoke chronic failure. There is no official confirmation of this information at the moment, nor is there any connection in the work of the liver with physical activity. Mildronate prevents the penetration of fatty acids into tissues at the cellular level, whereby the liver is protected from the accumulation of fats. In fact, Mildronate has a positive effect on her.
"Mildronate" can be used for a wide range of diseases, both due to the peculiarities of the effect on the human body, and because of the minimal interaction with drugs that the patient uses at the same time. All this has led to the fact that recently, “Mildronate” is prescribed more often - with a variety of diagnoses. At the same time, do not indulge in self-medication with its use - this can provoke a negative result.
How to use correctly?
In the package "Mildronate" there is always an instruction that describes in detail how to use the medication. If these are ampoules for injections, then they are ready for use. The instructions describe how to get the injection right, but it is better to contact a professional nurse if the situation allows.
When choosing "Mildronate" in the form of tablets, you need to remember: the product is swallowed whole, it can not be chewed. The same goes for capsules. Tablets should be stored in their original packaging in a dark place, away from children. Usually capsules, tablets are recommended to be taken if Mildronate is prescribed as an element of complex therapy against cardiovascular pathologies.
Doses and periods
The manufacturer recommends taking no more than one gram of Mildronate per day. The dose recommended by the attending doctor (again, if there are indications for this, doctor's advice) can be divided into several receptions. Usually Mildronate is used twice a day. The duration of the course is 30 days, but sometimes a longer duration is required.
"Mildronate" shows a good effect in cardalgia, provoked by problems with the production of hormones. With this diagnosis, “Mildronate” is prescribed in a dose of 500 mg, used once a day. When side effects occur, the dose is divided into two doses. In the prevention of the consequences of cerebrovascular accidents, Mildronate is used every day at a dosage of 500-1000 mg. The daily dose can be divided several times.
Diagnoses and application
In case of chronic problems of blood supply to brain tissue, Mildronate is prescribed daily at a dosage of 500 mg, the duration of the course varies about a month and a half. In some cases, the doctor recommends a second course, but not more than three in a year. For arterial pathologies, Mildronate is used twice daily.
With increased loads (intellectual, physical), Mildronate is used in the maximum daily dosage, dividing it into several doses. Typically, the duration of this course is three weeks, but a repeat is possible under the supervision of the attending physician. When using Mildronate, athletes must also adhere to the established daily limit of one gram. Usually, “Mildronate” is used for two weeks during preparation for the competition, and during the competition itself they drink the drug for up to 15 days in a row, after which it is necessary to take a break.
Mildronate and alcohol
Like some analogues, Mildronate (reviews, instructions confirm this) shows good results in treating people who are addicted to alcohol-containing drinks. With pronounced withdrawal symptoms, Mildronate is used four times a day. The maximum daily dose is doubled relative to other situations: it reaches two grams. Course duration - one and a half weeks.
With alcohol dependence and severe intoxication of the body, Mildronate can be used in the form of injections. On sale, the drug is presented prepared for use. When introduced into the body, Mildronate and other agents should not be mixed. It is not recommended to use sodium solution for diluting the medication. Introduction to a vein is often recommended for coronary diseases, and the drug is administered once a day in an amount up to a gram.
What to replace?
As can be seen from the reviews, the analogues of Mildronate (the instructions for the use of these drugs may vary) are represented by the following items on sale:
- "Meldonium";
- "Cardionate";
- Idrinol.
The first option is the cheapest of these. As can be seen from the reviews, for the most part, patients are more satisfied with imported medicines than domestic ones, but the price of such drugs is much higher.
Mildronate: Unpleasant Aspects
It is known that Mildronate can provoke a number of negative side effects. To prevent unpleasant experience, it is necessary to use the medication only under the supervision of a doctor. In case of poor tolerance, you should immediately notify the attending doctor about this to adjust the chosen course or replace the drug.
Quite often, patients taking "Mildronate" note low blood pressure. Some develop allergic reactions. The manifestation of dyspepsia is possible - the gastrointestinal tract is disrupted, gas formation in the intestine is activated. Possible appetite disorders, when a feeling of fullness accompanies even the intake of a small amount of food. When using "Mildronate" there is a likelihood of developing tachycardia, hyper-excitation.
Medical statistics do not contain any cases of overdose of Mildronate. At the same time, side effects are amplified if the maximum daily dose established for a particular patient is not observed. Mildronate belongs to the group of medicines that are safe enough for human life.