This article will present analogues of Actovegin.
This drug is a natural drug that affects the body's metabolic processes. The main active ingredient of the medication is a natural component, which is obtained from the calf’s blood extract, purified from proteins.
Most often, this tool is used in the field of neurology, cardiology and psychiatry, as well as an adjuvant in dermatology, ophthalmology and other medical fields.
Action spectrum
The drug "Actovegin" 200 mg and analogues have a very extensive spectrum of effects:
- at the cellular level accelerates metabolism;
- improves blood circulation;
- has an antioxidant effect;
- accelerates the healing process and tissue regeneration;
- eliminates complications after hypoxia and increases the resistance of body cells to oxygen starvation.
The drug "Actovegin" in the form of intramuscular injections and tablets is used for circulatory disorders in the brain, for encephalopathy and some cognitive disorders, after suffering traumatic brain injuries and surgical operations, as well as after strokes and with a decrease in vascular tone.
The gel and ointment of this drug is used for damage to the skin, various dermatological diseases, burns and wounds. Analogues of Actovegin should be selected by a doctor.
The disadvantages and advantages of a drug
The main advantage is the natural composition of this drug. In the absence of contraindications, this medication can be used during pregnancy without harm to the mother and fetus. Most often it is used to treat a variety of neurological diseases in children. The natural composition of this medication allows you to use it from the first days of a child's life. In addition, the big plus is that the drug "Actovegin" is well combined with some other medications.
Contraindications
Despite this, there are contraindications to the use of the drug "Actovegin", but they are very few. These include:
- pulmonary edema;
- kidney disease
- heart failure;
- fluid retention.
In addition, this medicine should not be used for hypersensitivity to the ingredients of the drug.
Adverse reactions
Despite the fact that the drug “Actovegin” is quite easily tolerated, there may be some side effects in the form of increased temperature and sweating, headaches, dizziness, gastrointestinal tract disorders, pain in the stomach, diarrhea, tachycardia, heart pain, urticaria, edema Quincke.
If such reactions occur, stop using the Actovegin drug and replace it with another, similar in effect, remedy.
In addition to side effects and contraindications, the cost of this medication can be considered a drawback
Analogues of Actovegin
If necessary, the drug "Actovegin" can be replaced with medicines that are equivalent in therapeutic effect. Such funds are called "analogues" or "generics." Despite the large number of analogues of this drug that can be found in any pharmacy, the replacement of the drug must be agreed with a specialist, in order to avoid some complications and adverse reactions.
So, we will consider the most popular analogues of Actovegin.
The drug "Solcoseryl"
This drug is the only one that coincides with the Actovegin medication in active substances, one of which is the extract from the blood of calves. The drug is a tissue regeneration stimulant and is a chemically standardized dialysate that contains low molecular weight components of the cell mass, as well as calf blood serum.
The drug increases resistance to hypoxia, activates cellular metabolism by enhancing glucose and oxygen transport, increasing intracellular utilization.
The healing effect of the Solcoseryl preparation is manifested in an increase in re-epithelialization after chemical burns of the eye, for example, with alkali, as well as after injuries and inflammatory processes.
The drug "Cerebrolysin"
This is an analogue of Actovegin in injections. This tool is a nootropic drug with a wide spectrum of action, which consists of peptides obtained from pig brain tissue. It is used to treat people of any age. The tool has a pronounced multimodal organ-specific action, that is, it provides neuroprotection, metabolic regulation, neurotrophic activity and functional neuromodulation.
“Cerebrolysin” increases the efficiency of energy aerobic metabolism in the brain, normalizes protein synthesis in it, protects neurons from the harmful effects of lactic acidosis, prevents the formation of free radicals and death of neurons under conditions of ischemia and hypoxia, and reduces the neurotoxic effect of amino acids. This medication is the only nootropic peptidergic agent with established neurotrophic activity, which is similar to the action of natural factors of neuronal growth, and, moreover, has a beneficial effect in violation of cognitive functions on the memory process.
This is confirmed by the instructions for use.
Analogs of gel "Actovegin" will also be presented.
The drug "Cortexin"
This medication is a nootropic substance and contains low molecular weight water-soluble polypeptide fractions. It has a pronounced nootropic, antioxidant, neuroprotective and tissue-specific action. Improves brain function, memory and learning, resistance to a variety of stressful effects, improves concentration. The drug has an effect that protects neurons from damage by neurotoxic endogenous factors and reduces the toxic effect of the use of many psychotropic substances. The active components inhibit the oxidation of lipids, increase the survival of neurons under oxidative stress and hypoxia, activate metabolism, and reparative processes improve the function of the cerebral cortex and the tone of the nervous system.
It’s easy to find cheap analogues for “Actovegin” injections.
The medicine "Mexidol"
This is an antioxidant drug that is used in psychiatry for toxic effects on the brain, neurotic disorders, to eliminate withdrawal symptoms. The medicine has a membrane protective, antihypoxic, nootropic, anxiolytic and anticonvulsant effect, increases resistance to stress and the body's resistance to the action of damaging factors.
The medication improves metabolism and blood circulation in the brain, microcirculation and blood properties, reduces platelet aggregation, stabilizes the membranes of blood elements during hemolysis, has a pronounced hypolipidemic effect, reduces cholesterol and enzymatic toxemia in pancreatitis. The use of analogues of Actovegin should be strictly according to the instructions.
Mechanism of action
The mechanism of action of this medication is due to its antioxidant, antihypoxic and membrane-protective action. The drug inhibits the process of lipid oxidation, enhances the activity of superoxide dismutase. Mexidol modulates the activity of enzymes and receptor complexes, enhances their binding to ligands, promotes the structural and functionality of biological membranes, transporting neurotransmitters, increases dopamine levels in the brain, enhances the compensatory activity of aerobic glycolysis, normalizes the metabolic process in ischemic myocardium, restores the electrical activity of the myocardium, reduces areas of necrosis, enhances coronary blood flow in areas of ischemia.
The drug also increases the activity of nitro drugs and favors the preservation of retinal and optic nerve cells in case of progressive neuropathies, the causes of which are hypoxia and chronic ischemia.
Cheap analogues for Actovegin injections can be purchased at any pharmacy.
The drug "Semax"
The drug "Semax" is available in the form of nasal drops and is a synthetic peptide agent. The medication has the original principle of a neurospecific effect on the nervous system and is considered a synthetic analogue of corticotropin, which has nootropic properties and is devoid of hormonal activity. This drug improves cognitive processes in the brain, increases mental activity, adaptation of brain cells to hypoxia, anesthesia and other damaging effects.
The drug is practically non-toxic both with a single and with prolonged use. Allergic, teratogenic, embryotoxic and mutagenic reactions are not manifested during treatment with this agent. The drug does not have a local irritant effect.
We examined the cheap analogues of "Actovegin" in ampoules.
Comparison of drug analogues
All analogues of this medication differ in pharmacological categories and active substances. However, if it is nevertheless taken to replace the Actovegin tablets with another drug, it is necessary to pay attention to the fact that each of the analogues also has some additional areas of its effect, which in some cases can cause certain side effects and allergic reactions.
Due to the identical composition, only the Solcoseryl medication is an absolute analogue of the Actovegin drug, therefore, in cases of need, experts give preference to this particular medication. Solcoseryl has a shorter shelf life, and Actovegin contains a special concentrate for long-term storage. This is their main difference. The cost of medicines is about the same.
Cerebrolysin, like Actovegin, is also a drug of animal origin. Both medicines are widely used for neurological diseases, but Cerebrolysin has a wider spectrum of effects and fewer contraindications. Their main difference is the ability to replace the functions of dead brain cells. The price of Cerebrolysin is slightly lower.
"Cortexin" differs from the drug "Actovegin" in that it has a milder effect on the body, however, the slower effect from its use also distinguishes it from this remedy.
Mexidol also has a broader therapeutic focus and, unlike the Actovegin medication, not only affects blood circulation and metabolism, but also restores cognitive functions and improves memory. However, the drug "Mexidol" is contraindicated during pregnancy and lactation.
Tablets
This form of release is represented by 3 generic "Actovegin":
- Curantil
- "Dipyridamole";
- "Vero-Trimetazidine."
The first two tools are absolutely similar to each other. Both of them have a myotropic vasodilator - dipyridamole. Thanks to this substance, blood microcirculation improves, and platelet aggregation also decreases, which contributes to the expansion of blood vessels.
An interesting property of Curantyl and Dipyridamole is their effect on human immunity. When taking these medications, the production of interferon increases, as well as the protective qualities of the body in the fight against viruses.
Vero-Trimetazidine is intended for the treatment of vascular disorders caused by ischemia, as a rule, in complex therapy. The active component of the drug is trimetazidine, which normalizes energy cellular metabolism, ensuring the maintenance of homeostasis during the transfer of potassium and calcium ions.
These are the main analogues of Actovegin in tablets.
Reviews
The opinions of patients who used the drug "Actovegin", as well as its analog preparations, are very mixed. Some of them adhere to the point of view that you need to use exactly the drug that was prescribed by the doctor, and not replace it with cheaper drugs. However, in cases of individual intolerance, Actovegin was successfully replaced by the drug Cerebrolysin and Semax, as evidenced by some reviews of other patients. They note that these drugs give a quick therapeutic effect, which helps to successfully treat some disorders in the nervous system.
Mexidol medication has also been well established for several years due to the fact that this drug has a very broad effect on the nervous system and metabolic processes. This determines its use not only in the treatment of general disorders, but also specific ones, such as, for example, serious mental disorders.
The medicine "Cortexin", judging by the reviews, is most often used in preventive practice and is prescribed to prevent exacerbations of certain diseases, to improve memory and learning abilities.
Analogues of Actovegin cream, as well as gel, are presented only by Solcoseryl.
Synonyms of ointment
The only similar local medicine besides Solcoseryl is Algofin.
The composition of the product from Actovegin is completely different, since it contains protein components (chlorophyll-carotene paste). Nevertheless, Algofin successfully copes with:
- trophic, purulent-inflammatory, radiation ulcers of soft tissues and mucous membranes;
- any burns;
- phlegmon;
- abscesses;
- pressure sores;
- aseptic, infected wounds.
We examined the analogues of the drug "Actovegin" on the active substance.