Using the medicine “Orungamine” it is possible to cure fungal diseases of the nails, as well as pathologies on the skin and mucous membranes. Its effect is due to the activity of itraconazole - this is the main component of this medication. Reviews about "Orungamine" are abundant.
The composition of the drug
For one capsule, 100 milligrams of the active ingredient, which is itraconazole, is present. The composition of "Orungamine" is described in detail in the instructions. Capsules are made of gelatin, dye and titanium dioxide, sucrose, sugar grains, hypromellose, sodium methyl parahydroxybenzoate and eudragit.
Indications
"Orungamine" should be taken in the following cases:
- In the presence of pityriasis versicolor and fungal keratitis.
- Against the background of dermatomycosis and candidiasis of the skin and mucous membranes.
- With thrush and onychomycosis, which is caused by yeast, mold and dermatophytes.
- Against the background of candidal lesions of the peritoneal organs.
- In the presence of systemic fungal lesions on the background of cryptococcosis, histoplasmosis, blastomycosis, aspergillosis and so on.
Healing properties
According to the instructions for use, "Orungamine" has antifungal properties. The main component of the drug is endowed with the property of suppressing the synthesis of ergoserol in the cell membranes of the fungus. This drug is very effective against dermatophytes and molds. Thus, it is used against trichophytosis, mycosporum, phytosporum, candida, aspergillus, histoplasma, fonceceia, cladosporitum, epidermophyton floccosum, cryptococcus, blastomy and so on.
After the dosage is taken, the highest concentration of the active ingredient in the blood is found four hours after use, it is better to drink the drug after eating - so that the bioavailability is higher. The drug "Orungamine" can easily accumulate in the tissues, in the skin it is very active four weeks after the completion of the treatment course. The withdrawal period is about two days. About twenty percent of the drug goes through the intestines. About thirty-six percent with urine.
Release Forms
The medicine is available in a gelatinous shell, inside spherical microspheres. The capsule has a blue opaque lid and a transparent body; 5 pieces are produced per plate. A cardboard box contains 1 package. "Orungamine" is not available in tablets.
Mode of application
The instructions for use with "Orungamine" indicate that the prescription of this drug depends largely on the diagnosis. In the presence of thrush, take two capsules twice within three days. If there is lichen, use two in a week. With dermatomycosis, take one pill fourteen days in a row.
With keratitis caused by a fungus, take one at a time for twenty-one days. If you have candidiasis of the mouth, use one pill for two weeks. In the event that the patient has a pronounced immunodeficiency, the dosage is doubled.
When infected with a nail fungus, take two capsules per day, but finally the treatment regimen should be agreed with the attending physician. In the presence of aspergillosis, two are used for one hundred and fifty days in a row, it all depends on the degree, and in addition, on the severity of the disease.
With systemic candidiasis, drink one capsule for thirty consecutive weeks. Against the background of cryptococcosis, two pills are used once a day (from two months to one year). In the presence of histoplasmosis, two are drunk twice for eight months. Against the background of sporotrichosis, one pill is consumed for three months. With blastomycosis, patients are prescribed two capsules twice, for six consecutive months. With chromomycosis, use two pieces once a day until six months.
With lesions of the nail plates, pulse therapy is prescribed. This type of treatment involves a seven-day course of 400 mg of itraconazole per day (two capsules twice a day). Onychomycosis of the nails on the hands requires two courses. Onychomycosis of the nail plates on the feet - three courses. You will also need a break in treatment lasting 21 days. Continuous treatment of onychomycosis consists in the use of 200 mg of the drug per day for a duration of 90 days.
Alcohol compatibility
Given the fact that in many situations it takes a long time to take this medication, many have the question of whether it is possible to combine alcohol with this antifungal drug. The answer will be negative, because alcohol greatly weakens the immune system, which leads to increased development of the disease, in particular, this drug may simply lose its medicinal properties. Thus, simultaneous administration is simply incompatible. From such an interaction, the load on the liver and digestion increases, which subsequently negatively affects the state of health.
Contraindications
It is impossible to combine the use of "Orungamine" with such drugs as "Terfenadine", "Cisapride", "Lovastin", "Quinidone" and "Midazolam". Do not recommend this medication during pregnancy. With caution, it is prescribed to children, and in addition, to nursing women if they have a serious history of heart disease.
Side effects
Judging by the reviews, “Orungamine” can cause various allergic reactions, along with an upset digestive system, headaches, nervous breakdowns, changes in the urogenital sphere, metabolic and water metabolism disorders, and all kinds of malfunctions in blood flow.
Terms and conditions of storage
You can store this medication for up to three years, away from children. It is advisable to keep the medicine in a dry place at a temperature of no more than twenty degrees.
Analogs of "Orungamine"
An analogue of this drug should include a medicine called "Orungal." The average price for this substitute is three thousand rubles per package. This tool is an absolute analogue to the active component. The form of its release is capsules, along with oral syrup. The advantages of this substitute are its effectiveness and quality. The obvious disadvantage is the high cost. Sometimes, against the background of its use, side effects may occur.
Another analogue of “Orungamine” is a drug called “Medoflucon”. Its average price is equal to seven hundred rubles per pack. Medoflucon medicine consists of fluconazole substance. This is a fairly popular active ingredient, which is most often used to treat thrush. This product is released in the form of solutions for infusion and pills intended for oral use. The advantages of a substitute are its speed, along with effectiveness, and the disadvantages are that it is not suitable for all patients.
Reviews on Orungamine will be presented below.
Reviews about the drug
They are responding positively to this medicine. On the Web, you can often find various comments in which consumers praise this drug.
For example, some write that “Orungamine” helps a lot in the presence of severe itching in the intimate area. It is reported that after a couple of days of taking it against the background of the effect of the drug, the patient becomes much better, and the itch, in turn, gradually decreases, and at the same time the unpleasant smell disappears.
In addition, people in reviews of “Orungamine” write that they did not notice any side effects during the treatment with this medicine. Thus, based on various comments of patients, it can be said that this medication is an effective and fast-acting drug.