Arterial hypertension is a fairly common vascular pathology. Hypertension, as it is also called, occurs at any age. This is a serious disease that requires careful treatment and control. Elevated pressure is fraught with complications that can lead to a significant deterioration in well-being, death. If you feel worse, you must consult a doctor to undergo an examination and start taking antihypertensive drugs.
The modern pharmaceutical market has a huge number of medicines that can bring pressure back to normal in a short time. One of the popular and effective remedies for hypertension is the drug Prestarium A (10 mg). Instructions for use describe how to properly take the product.
Basic data
The medication is made in the form of capsules of white or green color. The color of the medicine depends on the dosage of the drug. The main element in the composition of the drug “Prestarium A” is perindopril arginine in the amount of 2.5, 5 and 10 mg. The medicine belongs to the group of antihypertensive drugs that are considered ACE inhibitors. The drug has the following effects on the body:
- vasodilating effect;
- lowers the secretion of aldosterone;
- in the supine and sitting position, diastolic and systolic pressure decreases;
- OPSS decreases, which subsequently helps to reduce pressure;
- peripheral blood flow accelerates;
- the drug does not have withdrawal syndrome;
- restores the structure of arteries;
- reduces left ventricular hypertrophy.
A medicine is also prescribed for heart failure. Must be studied before starting therapy with the drug "Prestarium" instructions for use. At what pressure tablets are prescribed and at what dose, the doctor will tell you.
When to use the medicine?
The medication has the following indications:
- hypertonic disease;
- heart failure (chronic);
- stroke prevention;
- ischemia.
Also, the drug is prescribed to reduce the likelihood of complications after heart surgery.
Contraindications:
- Propensity to an allergic reaction, a history of Quincke's edema;
- hereditary angioedema ;
- renal failure;
- diabetes;
- lactose intolerance;
- the period of gestation;
- the period of breastfeeding;
- minor age;
- hypersensitivity to the elements in the composition of the drug;
- connective tissue diseases;
- taking diuretics, potassium-containing agents;
- hypertrophic obstructive cardiomyopathy;
- kidney transplantation.
Before starting therapy, it is necessary to study in detail all contraindications that relate to the Prestarium medical device. For pressure, the medicine is prescribed in an individual dosage, taking into account the severity of the disease.
Dosage
The medicine is taken in the morning at the same time. The daily rate depends on the clinical situation and the degree of pressure decrease during therapy. You can start taking 5 mg of Prestarium tablets and gradually increase it if necessary. The medicine is used both for monotherapy and in combination with other antihypertensive drugs. The maximum daily allowance should not be more than 10 mg. If together the patient drinks diuretics, then the medicine for pressure is prescribed in the smallest dose. Patients with cardiac pathology are prescribed a similar dose of the drug.
There is no reliable data on drug overdose. In exceptional cases, the following symptoms may develop:
- cardiogenic shock;
- sharp decrease in pressure;
- cough;
- anxiety;
- tachycardia;
- renal failure.
If intoxication occurs, then the patient needs to rinse the stomach, take an absorbent and begin to restore the water-electrolyte balance with the help of infusion therapy. Such measures must be carried out in case of poisoning with the drug Prestarium. The price of the drug in pharmacies in Moscow is about 460 rubles per package.
Drug interaction
You can not take the drug with the following medicines:
- aliskiren and aliskiren containing agents;
- potassium-sparing diuretics;
- potassium salts;
- immunosuppressants;
- Heparin
- "Estramustine";
- lithium preparations;
- hypoglycemic agents;
- "Baclofen";
- antidepressants;
- "Aspirin";
- sympathomimetics.
The antihypertensive effect can be enhanced with the simultaneous use with other antihypertensive drugs, vasodilators, including short and prolonged nitrates.
Side effects
Only as prescribed by a specialist should take the drug "Prestarium". Side effects may develop if the doctor's recommendations are not followed. The following symptoms should alert:
- parasthesia
- migraine;
- noise in ears;
- a strong decrease in pressure;
- drowsiness;
- visual impairment;
- cough;
- bronchospasm;
- asthenia;
- chest pain.
Such side effects are characteristic with a maximum dose of Prestarium A - 10 mg. Instructions for use describe under what symptoms it is worth increasing the daily rate of the medication.
If it was not possible to find the remedy in the pharmacy, the specialist will be able to choose the suitable substitute. The most popular analogues will be described later.
"Bee Prestarium"
The medicine belongs to the group of combined agents for the treatment of high blood pressure. The composition includes perindopril and amlodipine. The medication has similar indications for use. "Prestarium" and "Bee Prestarium" practically do not differ.
The drug has the following effects:
- reduces pressure (while the frequency of contractions of the heart does not change)
- increases peripheral outflow;
- increases outflow from the kidneys;
- lowers left ventricular hypertrophy;
- increases the elasticity of large arteries;
- expands the lumen of blood vessels;
- restores blood flow in the coronary vessels;
- reduces myocardial afterload;
- increases exercise tolerance;
- reduces the risk of heart failure.
Means "Be Prestarium" quickly enough helps to normalize pressure indicators. If the patient does not have a positive therapeutic effect, then the doctor prescribes an additional intake of a hypotensive agent of another group. This is the only way to achieve the desired result and improve well-being of hypertension. A positive effect is noticeable within a few hours after taking the medicine.
When is the drug used?
The tool has the following indications:
- arterial hypertension;
- cardiac pathology.
Contraindications to taking the means of "Be Prestarium":
- hypersensitivity to the components in the composition of the drug;
- lactose intolerance;
- hereditary angioedema;
- acute heart attack;
- pregnancy;
- lactation;
- impaired hematopoiesis;
- taking immunosuppressants.
The drug “Prestarium” has identical contraindications. The action of these two agents is based on a decrease in pressure and normalization of the heart.
The medication is prescribed for oral administration. The tablet is coated with a special protective film, so it is not recommended to chew it. It is necessary to drink medicine in the morning, after breakfast, preferably at the same time. The dosage of the drug depends on the severity of the disease, the individual characteristics of the patient's body. The daily norm should not be more than 10 mg. The same dosage is typical for the drug Prestarium (10 mg, as we have said, is the maximum dose). Exceeding this norm can lead to the development of side effects.
The drug "Perineva"
The tool refers to drugs - ACE inhibitors. Available in the form of white tablets in a dose of 4 and 8 mg. The composition of the drug includes perindopril erbumin.
Act:
- reduces diastolic and systolic pressure;
- accelerates peripheral blood flow;
- reduces OPSS;
- enhances renal outflow;
- reduces left ventricular hypertrophy.
Those who don’t know how to replace Prestarium should use the Perinev remedy.
Indications:
- chronic heart failure;
- arterial hypertension;
- prevention of re-stroke in patients with cerebrovascular pathologies;
- Ischemic heart disease. Reducing the risk of heart and vascular disease.
Indications for use "Prestarium" and "Perineva" are similar. But using any medication is necessary only after consulting a doctor.
Contraindications:
- if there is a history of angioedema of various etiologies;
- hereditary lactose intolerance;
- age up to 18 years;
- renal and liver failure;
- pregnancy;
- lactation;
- acute myocardial infarction.
With caution, tablets are prescribed for diabetes, blood diseases, low blood pressure. It is worthwhile to carefully study all the contraindications for taking the preparations of Perinev and Prestarium. The price of medicine in pharmacies in Moscow is about 260 rubles.
Dosage of the drug "Perineva"
The medicine is used once a day, in the morning, after eating. It is recommended that you first start drinking 4 mg of the drug, then, if necessary, increase the rate to 8 mg. For elderly patients, the dose should not exceed 2 mg.
Overdose can lead to the development of the following symptoms:
- pronounced decrease in pressure;
- violation of water and electrolyte balance;
- anxiety;
- cough;
- tachycardia;
- renal failure.
To eliminate the symptoms of an overdose, it is necessary to introduce drugs to the patient to stabilize the pressure and normalize electrolyte metabolism. Carefully observe the dosage that the doctor prescribed for the means of "Perinev" and "Prestarium." Instructions for use of these tablets contain data on the composition and characteristics of the reception.
Interaction with other medicines. Storage conditions
You can not take together:
- diuretics;
- potassium-containing foods and dietary supplements;
- lithium products;
- "Aspirin";
- hypoglycemic drugs;
- sympathomimetics.
The drug is stored at a temperature of no more than 25 degrees out of the reach of children. The pharmacy is available on prescription.
Means "Perindopril"
ACE inhibitor has a vasodilating property, reduces myocardial afterload, increases minute volume of blood and exercise tolerance. Indications for the use of Prestarium and Perindopril are also very similar.
The medicine is prescribed for such pathologies:
- chronic heart failure;
- arterial hypertension.
Contraindications:
- angioedema of various etiologies;
- pregnancy;
- lactation;
- hypersensitivity to the main substance.
Dosage of Perindopril
The initial dose of the drug can be from 1 to 2 mg per day at a time. You must try to drink the medicine at the same time and drink a little water. In heart failure, the dose is from 2 to 4 mg per day. With arterial hypertension, the maximum rate should not exceed 8 mg.
Co-administration with the following substances is not recommended:
- muscle relaxants;
- loop diuretics;
- tricyclic antidepressants;
- sympathomimetics;
- "Indomethacin";
- "Insulin";
- potassium-containing products.
If the doctor's recommendations are not followed, the following side effects may develop:
- dry cough;
- taste violation;
- diarrhea;
- cramps
- dizziness;
- migraine;
- itching
- rash;
- sexual abuse.
Before starting treatment, indications for use must be studied. "Prestarium", "Perindopril", "Perineva" - all these drugs can normalize the state of hypertension. But self-medication is not worth it. Any drug should be prescribed by a doctor.
special instructions
All described drugs are prohibited for use in childhood. The product must be stored for no more than two years at a temperature of 25 degrees in a dark and inaccessible place for babies. In case of impaired renal function, it is necessary to adjust the dose of the drug and make appropriate analyzes. During the treatment process, you should refrain from hemodialysis using polyacrinonitrile membranes. Patients with a low content of sodium and fluid should be prevented water-electrolyte disturbances.
All patients with a diagnosis of "hypertension" need to monitor blood pressure twice a day. All data should be entered in a notebook and provided to the therapist at the appointment. Based on these results, the doctor will be able to review the dosage of the drug. If there is a need, then the daily norm should be increased to maximum values in order to improve the patient's condition.
Periodically, the patient is prescribed to undergo an ECG procedure that allows you to track changes in the work of the left ventricle of the heart. Only by the joint efforts of the doctor and the patient can the process of hypertension be stopped, thereby prolonging the patient's life. It is worth considering that hypertension requires regular therapy. Many have to drink pills throughout their lives.
Detailed information contains on the tool "Prestarium" instructions for use. At what pressure to take pills, when it is worth refusing therapy - the doctor can also tell about everything. It is not worth neglecting the recommendations.