Unfortunately, modern realities and the fast pace of life are forcing many people to live in constant stress. Neurosis and depression negatively affect not only our mood, but also the entire state of the body, so you need not to leave them unattended, constantly postponing a visit to the doctor, and start treatment on time. Of course, many of us know that the pharmacological market offers a huge selection of different depressants and tranquilizers, but not all of them are equally effective. Specialists often recommend using Grandaxin tablets to treat neurosis. Instructions for use, reviews and analogues of this tool we will consider in detail in our article.
More information about the composition of the drug and its form of release
The composition of the drug is its most important component, because it will depend on it and the effectiveness, and the possibility of side effects, and even its cost. The main active ingredient of "Grandaxinum" is the instructions for use called the component tofisopam, which is a tranquilizer that has an anxiolytic effect on the human nervous system. Doctors call it a significant advantage that it does not have a sedative effect, that is, a person will not feel constant drowsiness and fatigue after starting treatment. For many working patients who do not have time for sick leave, this factor is crucial.
Instructions for use "Grandaxinum" indicates that the drug is available exclusively in the form of tablets. They can be recognized by their characteristic flat and rounded shape and white color. However, sometimes grayish tablets are allowed. Each pill contains 50 mg of active substance. At the same time, the tablets do not have a pronounced smell, and you can recognize them by engraving "Grandaxin", indicated on one of its sides. Also, the composition of the drug includes other auxiliary components that are standard for many drugs. For example, stearic acid, lactose monohydrate, talc, microcrystalline cellulose and potato starch can be isolated.
For ease of use, tablets are available in cardboard boxes. In them you can find not only blisters in which the pills are packed, but also detailed instructions for using Grandaxin. It is necessary not only to study it before taking it, but also to seek advice from a neurologist or therapist so as not to aggravate your condition. In addition, without a prescription prescribed by a specialist, it is simply impossible to buy a drug - a pharmacy will simply refuse to sell it without relevant documents. But the shelf life of the tablets is 5 years, but they need to be stored in a warm and dry place.
What are the indications for its use?
It is up to your doctor who is well acquainted with the medical history to decide whether to take this drug or not. Since the drug belongs to tranquilizers, it is prescribed for the correction of disorders of the nervous system. Instructions for use "Grandaxinum" indicates that its active substance has a pronounced anxiolytic effect and moderate stimulating activity, so this medicine is suitable for the relief of symptoms of the following diseases:
- Various neurosis-like conditions, including the neurosis itself. This category usually includes reduced activity in the patient, severe anxiety, apathy and obsessive experiences. The drug also helps with vegetative disorders, it is also used to maintain the nervous system with increased emotional stress.
- Depression, which is accompanied by moderate clinical symptoms. This also includes the reactive form of this disease.
- Menopausal syndrome in women suffering from menopause. Typically, the drug is used as part of complex therapy with hormonal agents.
- Premenstrual syndrome in women.
- Syndrome of alcohol withdrawal. The drug helps to reduce the overall level of nervousness and anxiety in patients.
- Cardialgia. In this case, the instructions for the use of "Grandaxin" says that the tablets can be used both for monotherapy and for complex treatment in combination with other agents.
- Mental adaptation disorders - the most common pathology here is post-traumatic nervous system disorder.
It is also worth noting that the instructions for the use of "Grandaxin" indicate that in some cases the drug can be prescribed to patients suffering from myasthenia gravis, neurogenic muscle atrophy and myalgia. However, they do this only if the patient is contraindicated with drugs that have a characteristic muscle relaxant effect.
More on contraindications for use
Despite its popularity and availability, not all patients can take tablets. In the presence of some pathologies, taking the medicine can only aggravate their course and harm the body. Therefore, it is important to inform the specialist in time about all the diseases the patient has, so that he can, if possible, choose another remedy.
So, for example, the instructions for the use of the drug “Grandaxin” indicate that its administration is strictly contraindicated for people who have a history of the following pathologies:
- hypersensitivity to lactose, intolerance to galactose or any other components that are part of this tool;
- neurological conditions, expressed by increased patient aggressiveness, as well as excessive psychomotor agitation and severe depression;
- conditions in which breathing stops during sleep;
- respiratory failure in a patient who is in the stage of decompensation.
The instruction of “Grandaxin” also indicates that tablets may be prescribed with caution to patients who suffer from epilepsy, acute respiratory failure, as well as some organic brain lesions. However, in this case, treatment should be carried out under the strict supervision of a specialist.
Can side effects appear after administration?
Taking any drug will never be completely safe for each patient, because the human body always responds individually to the components of the drug. Therefore, not a single patient is safe from the appearance of side effects. And if you feel worse after taking the pill, then it is better not to continue treatment, but to consult a doctor and report unpleasant symptoms.
The instructions of “Grandaxin” describe that patients most often complain of the following side effects:
- frequent headaches, excessive irritability, increased excitement, the appearance of confusion - such symptoms appear on the part of the nervous system;
- the increase in seizures in patients suffering from epilepsy;
- increased tension in the muscles, a feeling of discomfort and pain in them;
- the appearance of severe skin itching and redness, much less often - exanthema;
- respiratory depression, which can lead to its complete stop, especially in a dream;
- from the gastrointestinal tract, nausea, bloating, constipation, dry mouth and pain in the abdomen may appear, in individual cases, congestive jaundice develops.
Grandaxin tablets: instructions for use
To achieve the maximum effect of treatment with any drug, it is important to follow all the recommendations that the doctor tells the patients about. And in this case, the instruction of Grandaxin tablets indicates that the dosage and order of therapy should be individually selected by a specialist, based on the severity of the pathology, the patient’s condition and the course of the disease. The individual sensitivity of the patient to the components of the drug is also evaluated.
As a rule, for the complex treatment of nervous disorders, doctors recommend that adults take 1-2 tablets in the morning, afternoon and evening. In this case, the maximum possible daily dose should not exceed 300 mg of tofisopam, that is, 6 pills. In some cases, a single dose of the drug is allowed to quickly stop unpleasant symptoms. Doctors are allowed to drink 1-2 tablets at a time.
For elderly patients, the instruction of “Grandaxin” recommends halving the standard dosage in order to prevent a general deterioration of the condition. The same goes for people suffering from chronic renal failure or other serious kidney diseases.
What is the danger of overdose and how to treat it?
As mentioned above, the instructions of the drug "Grandaxin" indicates that the maximum daily dosage should not exceed 300 mg of tofisopam. Therefore, you do not need to get involved in taking pills, otherwise serious consequences cannot be avoided. If you accidentally ate more than 6 tablets in a day and feel unwell, you should immediately seek medical help from a doctor.
As a rule, dangerous symptoms appear only after a copious overdose. They are manifested primarily by severe inhibition of the central nervous system. The patient begins vomiting, confusion appears. In some cases, general depression of consciousness, and sometimes epileptic seizures, can be observed. If assistance is not provided on time, then a person may even fall into a coma.
Doctors, after detecting symptoms of an overdose, first complete a gastric lavage, and then prescribe a large amount of activated carbon to reduce the absorption of the drug. Then symptomatic therapy is carried out, aimed at maintaining normal physiological parameters. For example, if a patient stops breathing on their own, then they turn on artificial lung ventilation. To maintain heart function, dopamine is often administered. Studies have also shown that the use of dialysis for the speedy removal of the drug from the body is not effective.
Are tablets prescribed for pregnant women and young children?
As a rule, during pregnancy, women very carefully choose their medications so as not to harm the developing fetus. The drug "Grandaxinum" (50 mg) does not recommend instructions for use in patients carrying a child. Moreover, a strict ban applies only to the first trimester of pregnancy. In other cases, you can take the drug, but only if there is a strong need for treatment, and there is no way to choose another analogue. In addition, the active substance is found in the breast milk of a woman who takes "Grandaxinum", therefore, during lactation, tablets are also forbidden.
Children are not prescribed the drug, as specialists have not yet studied in detail the effect that the tablets have on the growing body and its nervous system. Therefore, you can take the medicine only from 18 years after the approval of the attending physician.
Concomitant use of tablets with other drugs
Not all drugs can be taken together, as they can enhance or, conversely, reduce the effect of treatment. Grandaxinum (50 mg) is no exception. The instruction describes in detail what to use simultaneously with other drugs that suppress the central nervous system, it is impossible. Because they can enhance each other's effectiveness, which will lead to increased sedative effect. In this case, the patient will feel severe tiredness, drowsiness. Sometimes this combination of means can even lead to respiratory depression.
On the contrary, the simultaneous administration of "Grandaxin" with hepatic enzyme inducers can weaken the effect of the drug. They will contribute to a more rapid elimination of the drug from the body, which, in turn, will reduce the effectiveness of therapy. In any case, before starting the reception, you should consult with a neurologist or therapist who will tell you with which drugs these tablets should not be combined.
The main analogues of this drug
This remedy is not suitable for all patients, therefore it is also worth mentioning about the analogues of Grandaxin. Instructions for use do not recommend to treating people at their own request to replace one drug with another. And although they have the same active substance in their composition, each medicine has an individual list of side effects and contraindications. If the tablets did not suit you for any reason, it is best to consult a doctor and ask him to prescribe another remedy.
It should be noted that there are few analogues based on tofisopam. The most popular among them is the drug of the same name. But drugs that have the same therapeutic effect in pharmacies can be found a lot. We list the main ones:
- Afobazole;
- Tazepam
- "Neural";
- Relanium
- Diazepam
What are the benefits of the medicine in the reviews of patients and doctors?
Some patients like to study information not only about the instructions and analogues of "Grandaxin", but also about the reviews that people who are treated with this tool and the doctors who prescribe it for patients leave. As a rule, both of them are satisfied with the effect that the tablets have on the body. In the responses, they also indicate that the drug has its drawbacks, but the low price justifies their presence.
Among the main advantages, patients primarily highlight high efficiency, which is combined with the mild effect of the drug on the body. Anxiety, fear and other nervous disorders disappear after a few days of taking. In this case, patients do not feel severe fatigue and decreased concentration. Therefore, they can fully work and drive a car without discomfort. At the same time, there are practically no side effects during its use, which is also liked by doctors and patients.
Negative feedback about this tool
Grandaxin's instructions note that the drug has a mild effect on the body, so it does not help against serious diseases of the nervous system. Reviews this statement confirms, as sometimes patients indicate in them that the tablets did not help them. In this case, they were forced to consult a doctor for a more effective remedy. Some people think that the cost of the drug is quite high. In rare cases, patients note that after the start of administration, they had a rapid heartbeat. Doctors confirm that sometimes the manifestation of side effects only increases the anxiety of patients, reducing the positive effect of therapy to zero. Some patients noticed that after the start of taking their appetite decreased greatly, a feeling of nausea appeared. A negative point in people in the reviews also consider the presence of withdrawal symptoms after stopping the intake. Therefore, after completing the course of treatment, you have to take pills for some time to prevent a sharp deterioration in well-being.
Draw conclusions
An effective and safe remedy is called "Grandaxin" instruction. The price of 60 tablets also makes the drug attractive for patients who cannot afford expensive treatment. As a rule, such a package can be bought for about 350 rubles. The exact cost of the pills will depend on the region in which they will be purchased. Patients and specialists usually respond positively about this tool, especially if you use it, strictly observing the doctor’s instructions.