In the article, we consider the most effective medications for osteoporosis.
The drugs are presented in a fairly wide range, however, among them it is impossible to choose the best remedy that can cure absolutely all diseases. Treatment directly depends on the degree and stage of the pathology. Doctors choose medicines based on the individual characteristics of the body of a patient.
Medication for this disease is pathogenetic in nature. Since osteoporosis is formed against the background of a decrease in bone density, its therapy is aimed at replenishing minerals, and, in addition, at increasing the strength of bone tissues. Osteoporosis requires a comprehensive approach from patients, as a rule, people are prescribed drugs that belong to several pharmacological groups at once.
The treatment of osteoporosis with drugs and therapies will be described below.
The basic principles of treatment
Fracture consolidation is an essential physiological process necessary for survival. Weak bone fusion in the body provokes not only a sharp decrease in the functional activity of the supporting and motor systems, but also significantly worsens the quality of human life. After fractures, severe deformations can occur. The main reason for such deformations can be incorrect matching of the bone fragment, leading to curvature or shortening of the limb, and, in addition, to a pronounced limitation in motor activity and movement. Osteoporosis medications restore broken bones to their former strength, preventing relapses of chronic pathologies.
In recent decades, pharmacological drugs have been synthesized for the treatment of osteoporosis, in which the relative risks of vertebral fractures were reduced to seventy percent, and the proximal femur to fifty-one percent.
Tactics with the treatment of osteoporosis depend on the degree of diagnosed degenerative changes and the stage of the disease.
- For example, a primary disease that can develop during the period of natural menopause with a decrease in the production of sex hormones in the female body is isolated. Therefore, drugs for hormone replacement treatment and bone mass increase may be included in the treatment regimen.
- The secondary form of osteoporosis occurs in patients, as a rule, after taking pharmacological drugs, and, in addition, as a result of diseases of the endocrine, immune, cardiac and vascular systems, as well as against the background of the development of pathologies of the digestive tract. Treatment of bone fragility is aimed at eliminating the causes of the disease.
In the main treatment, drugs are used that affect the metabolic process in the bone structure. Such medicines improve the absorption of trace elements of calcium. In order to increase therapeutic efficacy, such drugs are used for a long time, without any interruptions. Symptomatic therapy plays a huge role, which is aimed at facilitating the well-being of a person. Nonsteroidal drugs can be used along with antispasmodics, muscle relaxants, painkillers and balanced vitamin complexes.
Next, find out what doctors primarily pay attention to when choosing the main drugs for the treatment of osteoporosis.
What do doctors pay attention to when choosing a medicine?
When choosing the most effective medication for osteoporosis, doctors take into account many factors, for example, it is important to pay attention to the age of the patient, the results of laboratory and instrumental studies, and, in addition, the presence of a chronic history of history.
Medicinal preparations must necessarily fulfill the main tasks of treatment, preventing the development of further destructive and degenerative changes in the supporting system. A properly prescribed medication can suppress enhanced resorption, stimulating reduced bone formation, which significantly increases the mineral density of bones, improving their condition and reducing the likelihood of new fractures.
Choosing the Right Osteoporosis Medication
An anti-osteoporotic agent must necessarily reduce the likelihood of fractures that are localized in the vertebrae and in the proximal hips. Such bone injuries are the cause of the most dramatic medical and social consequences, especially in elderly patients.
Effective Osteoporosis Medicines: Bisphosphonates
This category of drugs is the basic component of the treatment of patients with osteoporosis. Basically, bisphosphonates are recommended for women during postmenopausal periods. Such medicines restore bone density, preventing fractures. True, these drugs for osteoporosis are distinguished by an extensive list of side effects and contraindications. It is important to note that before using medicines from the group of bisphosphonates, it is necessary to perform a comprehensive examination to exclude all contraindications.
What are the best drugs for treating osteoporosis?
The drug "Bonviva"
The active ingredient of the drug "Bonviva" is ibandronic acid. Together with auxiliary ingredients in the composition, it can effectively reduce bone destruction processes, stopping resorption. The drug "Bonviva" is produced in tablet format, and, in addition, in the form of injections. As a rule, Bonviva pills in a dosage of 150 milligrams are sufficient to use only once a month, and for injection therapy it is recommended to perform one injection every three months.
Bonviva is prohibited for patients suffering from the presence of individual sensitivity to the ingredients of this medicinal composition. Pregnant women and children, this remedy is contraindicated. With great caution, you need to take this medicine in the presence of osteoporosis for those patients who have a history of digestive tract pathology.
The medicine for osteoporosis "Zometa"
The active component in this case is zoledronic acid, which acts on osteoclasts. This medication is released in the form of a concentrate. Immediately before use, 4 milligrams of the drug is diluted with 100 milliliters of saline or dextrose. This medication is administered by the intravenous drip method. It is enough to put the dropper only once every six months.
Medication "Aklast"
This drug acts as an analogue of "Zometa". Its main difference is its course, for example, one dropper is usually prescribed once every two years. True, the opinions of experts regarding “Aklasts” vary significantly, since the drug in question has a lot of various side effects.
The medicine "Forosa"
The drug “Forosa” is produced in the form of tablets. The active ingredient is sodium alendronate. This medicine is able to repair bone tissue, but it does not directly affect bone formation. This bisphosphonate is able to restore bones by activating osteoclasts, but the process itself is carried out exclusively in damaged areas.
This medication has been developed and is available exclusively for the treatment of osteoporosis. The medicine “Forosa” significantly reduces the percentage of bone fractures in the presence of pathologies of any localization. Forozoj treatment involves taking one tablet once a week. This dosage is enough to effectively affect the whole body.
We continue to review the means and drugs for the treatment of osteoporosis.
Calcium preparations as an effective tool for the treatment of osteoporosis
Calcium citrate carbonates can regulate and optimize bone metabolism. Basically, these drugs consist exclusively of calcium. These tools include:
- Calcium gluconate. Among single drugs, this is the most affordable. The medication in question is prescribed in tablets, and, in addition, in injections from osteoporosis.
- Treatment with calcium lactate. This medicine is classified as an antioxidant supplement.
- Use of calcium glycerophosphate. This mineral supplement is able to normalize tissue metabolism in the tubular bones. Such medicine is sold in pharmacies in the form of powder and pills. The most effective calcium preparation for osteoporosis will help the doctor choose.
As a rule, experts recommend treating older people with senile osteoporosis with calcium-based drugs. These drugs are suitable for the treatment of pregnant women and children.
Below we consider the best drugs for osteoporosis in women.
The use of anabolic steroids for women
Such drugs are prescribed by specialists in cases where the treatment lasts for years. Steroids can accelerate bone growth, slowing down metabolic processes. These drugs are used to treat osteoporosis among women during the menopause.
Among adverse reactions, hirsutism along with changes in voice may be noted. Sometimes patients may complain of changes in the subcutaneous and fatty layers.
What is the most effective cure for osteoporosis in injections?
In treatment, the most preferred are anabolic steroids of prolonged exposure, for example, Retabolil. The active ingredient in Retabolil is nandrolone decanoate. This medicine is given as an injection for injections.
Among the adverse reactions in the course of treatment with such agents, patients have serious violations in the endocrine system. In this regard, during the course of therapy, hormonal background should be regularly studied.
Tablets of osteoporosis are also no less popular.
Active Vitamin D Metabolites
Vitamin D can increase the absorption of calcium from the digestive system, and also reduces the leaching of this trace element from bone tissue. Indications for treatment are the presence of steroid and senile osteoporosis, and, in addition, calcium malabsorption syndrome. The following drugs are the most popular drugs in this group:
- A medicine called "Calcium-D3." In the composition of the presented medicinal product, in addition to the synthetic substitute for vitamin D, calcium is included. This medicine is available in the form of chewable tablets. This medicine has a very pleasant fruity taste.
- The medication "Ideos". This medicine regulates calcium metabolism by restoring bone tissue and also promoting bone mineralization.
- The medicine "Calcitriol". This medication is often prescribed in the presence of a compression fracture of the spine, since this remedy relieves pain.
When carrying out the course, specialists recommend reducing the intake of chicken eggs and butter in the diet, since it is likely that hypercalcemia will develop.
Estrogens as another category of drugs for women with osteoporosis
This category is intended for the treatment of women with postmenopausal osteoporosis. It is advisable to use estrogens as a means for preventive treatment. Women who are over sixty-five years old are not prescribed these drugs because of their extremely low effectiveness at this age. Among the drugs of this pharmacological group, there are:
- A medication called Estrofem. This drug can regulate a woman’s menstrual cycle, preventing calcium from being washed out. They release the medicine in tablet format. The course of therapy, as a rule, is six months.
- Use of Livial. This medication is prescribed to women a year after the completion of menstruation. According to statistics, the use of "Levial" in the early stages of postmenopausal women increases bone density by an average of four percent. In later periods, this figure increases by as much as five percent.
It is worth noting that when prescribing the above drugs, it is necessary to be regularly examined by a gynecologist, since any hormonal medications can affect the mammary glands, and, in addition, the myometrium.
And what kind of painkillers for osteoporosis is better to get?
Analgesics from the non-opioid category
In the event of pain resulting from a compression fracture, people suffering from osteoporosis are prescribed non-opioid drugs that have analgesic and anti-inflammatory properties. True, these drugs do not have any effect on the underlying disease at all, and prolonged use of analgesics is fraught with the onset of diseases in the digestive system.
There should be a comprehensive and timely treatment of osteoporosis with drugs. Features of therapy also include the use of fluoride preparations.
Fluoride preparations
These drugs are prescribed by doctors for osteoporosis in order to increase bone mineralization. Specialists are advised to be treated with fluoride preparations in the presence of osteoporosis that arose due to the use of glucocorticosteroid drugs. In addition, a pronounced effect can be observed in the case of the use of fluoride-based drugs for the treatment of women in the menopause.
Density of vertebral bones may increase by four or five percent per year. Fluoride medications can only be treated after confirming a diagnosis of osteoporosis. The most recommended among fluoride preparations are:
- A medicine called "Corereron." The format of its release are tablets. Treat with the help of "Koreberona" mainly elderly people suffering from senile osteoporosis. This medication has many adverse reactions.
- The medication "Ossin." This medicine is available in the form of dragees and pills with different flavors. This drug is recommended not only for adult patients, but also for children. It is usually prescribed to support the level of fluoride in the human body. This medicine can be used for several years. The list of drugs - drugs for the treatment of osteoporosis is quite extensive.
Fluorides are very effective in the treatment of osteoporosis with the presence of lesions of the spine. Among adverse reactions, joint pain can often be observed along with digestive disorders.
Everyone wants to find the most effective cure for osteoporosis.
Calcitonin treatment
This category combines drugs that are also high in calcium. These medical products fully prevent bone destruction. Doctors recommend using steroid, senile, or postmenopausal osteoporosis with calcitonins. The most convenient form of release is a nasal spray.
Drug treatment of osteoporosis should only be carried out under the supervision of a physician.
The drug "Sibacalcin"
The medicine "Sibacalcin" contains synthetic calcitonin in its composition. This medication is released in the form of a dry powder intended for injection in ampoules of 0.25 or 0.5 milligrams each. Dosage is selected individually. Sibakalcin medicine is taken as a course for five months as a treatment.
What else to treat osteoporosis with what medicines?
The medicine "Forteo"
This medication is also recommended by specialists for osteoporosis. This medicine is prescribed for the treatment of a severe or advanced form of the disease. This medication is a synthetic thyroid hormone that increases bone density. A drug called "Forteo" is taken daily, the course of therapy depends on the result of a clinical examination.
It is worth noting that the drug in question can also be injected. The effect of calcitonins can be revealed very quickly, however, their beneficial compounds are also rapidly leaving the body. In addition, such drugs can be highly addictive against the background of prolonged use.
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And there are a lot of the most effective medicines for osteoporosis in today's pharmaceutical market. The main thing, according to doctors, is to take into account all the nuances and health characteristics of a particular patient. And only then will it be possible to choose the most effective remedy for osteoporosis.