Surely many people know such a drug as "Lazolvan Rino." The instruction for this remedy is always enclosed in the package along with the medicine. In the event that you have never used the medication mentioned, then we will describe how to do this in the presented article. From it you will learn about whether it is possible to use this drug during the period of gestation and during lactation, what indications, contraindications and side effects the drug has, etc.
Form of release of the drug, its composition and packaging
In what form can I buy a tool like Lazolvan Reno? The instruction of this drug says that it goes on sale in the form of a metered-dose nasal spray (can also be found in the form of drops). It should be noted that the aforementioned drug has a clear pale yellow color, as well as a pleasant aroma of eucalyptus.
The active ingredient of the drug is tramazoline hydrochloride (used in the form of tramazoline hydrochloride monohydrate). The medication also contains excipients in the form of benzalkonium chloride, citric acid monohydrate, sodium hydroxide, povidone, hypromellose, glycerol, magnesium sulfate heptahydrate, calcium chloride dihydrate, magnesium chloride hexahydrate, sodium hydrogen carbonate, sodium chloride, cineole (eucalyptol), (L-menthol), racemic camphor and purified water.
The drug "Lazolvan Rino", whose instructions will be discussed a little below, is available in dark glass bottles, which have a metering device and a nasal adapter. The medicine is placed in a cardboard box.
Pharmacodynamics of the drug
What is the medicine "Lazolvan Reno"? Instructions for use informs that this tool is a vasoconstrictor drug, which is intended for local use. Nasal spray is used in ENT practice
The active component of the drug causes vasoconstriction. After applying to the mucous membranes of the nose due to the vasoconstrictor effect, the medication significantly reduces swelling. As a result, the patency of the nasal passages is restored quite quickly, and breathing is facilitated.
How long does the drug "Lazolvan Rino"? The reviews of patients and doctors suggest that the effect of this medication begins already after the first 5 minutes after use. The therapeutic effect lasts about 8-10 hours.
Pharmacokinetic properties
There have been no pharmacokinetic studies of this medication in humans. However, the pharmacokinetics of tramazoline has been studied in rabbits, rats, and monkeys. As a result of this, it was proved that after using the drug intranasally it is absorbed in an amount of 50-80%.
It should be noted that tramazolin, as well as its metabolites, are distributed in almost all internal organs. Moreover, its maximum concentration is noted in the liver.
After topical use, the main metabolites are found in urine. The terminal half-life of the substance is 5-7 hours.
Indications
For what deviations can the doctor prescribe the herbal preparation "Lazolvan Rino" (drops, spray)? This tool is used to treat the following diseases:
- swelling of the mucous membranes of the nose, as well as its congestion, which was caused by hay fever or acute respiratory infections;
- rhinitis and hay fever ;
- otitis media (eustachitis) and sinusitis (to facilitate the outflow of the contents of the sinuses).
Contraindications
Are there any contraindications such as "Lazolvan Reno"? The instruction of the drug informs that it can not be used in the following conditions:
- atrophic rhinitis;
- angle-closure glaucoma;
- operations on the skull, which are carried out through the nasal cavity;
- hypersensitivity to tramazoline hydrochloride or benzalkonium hydrochloride, as well as to other components of the drug;
- in childhood - up to 6 years.
Careful reception
The medicine “Rino Lazolvan” (spray) should be used with extreme caution in patients with heart disease, arterial hypertension, prostatic hyperplasia, hyperthyroidism, porphyria and pheochromocytoma. In the presence of such deviations, the medication should be used only as directed by the doctor. This is associated with an increased risk of systemic absorption of the drug.
Special care should also be taken when taking tricyclic antidepressants, MAO inhibitors, antihypertensive and vasopressor drugs.
Dosage and methods of use
How should I use the "Lazolvan Reno" nasal spray? Analogues of the drug and the medication itself are prescribed to adults and children over 6 years of age by 1 injection in each stroke of the nose. This procedure can be performed up to 4 times a day. Do not use the spray for more than a week without prescribing a doctor.
Before injecting the drug, it is necessary to clean the nasal passages well. Then you should adhere to the following scheme:
- Remove the protective cap.
- Before the first use, carry out several injections into the air (so that a stable cloud of aerosol appears). Only then will the metering device be ready for use.
- Insert the tip into the nasal passage, and then give one injection.
- Repeat the procedure for another nose stroke. After removing the tip of the device, take a regular breath.
- Put on the protective cap.
After each use of the drug, be sure to clean the tip.
Overdose
What symptoms of an overdose will occur if the drug "Lazolvan Rino" is used incorrectly (the price of the drug will be presented below)? Signs of this condition may include the following: an increase, and subsequently a decrease in blood pressure, tachycardia, the development of reflex bradycardia, shock, and a decrease in body temperature.
In children, intoxication can lead to effects on the nervous system with the development of coma, seizures, bradycardia and respiratory depression. Signs of central nervous system stimulation include hallucinations, anxiety, cramps and agitation. Symptoms of depression of the nervous system include lethargy, lowering body temperature, drowsiness, and coma.
The following conditions may also be signs of an overdose: fever, mydriasis, cyanosis of the lips, miosis, pallor, increased sweat, impaired cardiovascular system, respiratory failure and psychological disorders.
In case of a nasal overdose, immediately rinse or clean the nose. In some cases, symptomatic therapy may be required.
Side effects
Can side effects develop after using Lazolvan Rino spray? The patient reviews say that in some cases, this drug really causes undesirable reactions, namely:
- dizziness, drowsiness, violation of taste sensations, headache;
- restlessness, insomnia and hallucinations;
- arrhythmia, palpitations, tachycardia and increased blood pressure;
- nasal discomfort, dry nose, swelling of the nose, rhinorrhea, nosebleeds, and sneezing;
- nausea
- hypersensitivity;
- rash, swelling of the skin, and itching;
- fatigue.
Lactation and pregnancy
Is it possible to use the nasal preparation "Lazolvan Rino" during pregnancy? Long-term experience using this product shows that it does not negatively affect the bearing fetus. As for the safety of use during lactation, it is not confirmed.
It should be specially noted that the drug in question cannot be used in the 1st trimester of pregnancy. At later dates, as well as during lactation, the use of a medication is allowed only after consulting a doctor.
special instructions
In the event that after 7 days of treatment with the drug in question the positive dynamics did not appear, it is necessary to decide on the abolition of the drug or on the replacement of the therapy. However, it should be noted that prolonged use of a nasal vasoconstrictor spray can lead to nasal congestion, the development of chronic inflammation and atrophy of the mucosa.
Avoid contact with eyes.
Studies on the effect of nasal agents on the ability to drive machinery and cars have not been conducted. However, it should be noted that when using this medication, the appearance of such undesirable effects as drowsiness, dizziness, hallucinations and fatigue may occur.
The price of the drug and its analogues
Do you know how much the Lazolvan Reno Nasal Spray costs? The price of this drug in different pharmacies may vary. Thus, the cost of a dosed product depends on the manufacturer and the margin on the product. On average, for 10 ml of medication you will have to give about 275 Russian rubles.
The following drugs are analogues of this remedy: Ambrohexal, Ambrolan, Ambrobene, Bronchorus, Vicks Asset, Ambrolor, Deflegmin, Ambroxol, Lazongin, Medox, Ambrosan "," Remebroks "," Flavamed "and so on.
Reviews on nasal spray
According to patients, the nasal spray "Lazolvan Rino" effectively eliminates nasal congestion, as well as relieves swelling and facilitates the outflow of the contents of the sinuses. However, it should be noted that there are a large number of people who complain of side effects that occur after using the drug. The most common side effects are dizziness, headaches, fatigue, itching and swelling of the skin.
It cannot be said that most patients are extremely dissatisfied with the cost of the drug. In their opinion, the price of this nasal product is unreasonably high. Although experts say that for one course of treatment only one package of the drug is required. Thus, therapy is not very expensive, but as effective as possible.