Lidocaine hydrochloride: instructions, description and analogues of the drug

There are many indications for the use of a local anesthetic. In medical practice, drugs are widely used that can cause blockade of nerve nodes and peripheral nerves. Anesthetics are also very popular in cardiology practice. They are used for the treatment and prevention of ventricular arrhythmias that accompany acute myocardial infarction, with glycoside intoxication and anesthesia. Quite often, doctors use the drug "Lidocaine hydrochloride" (2%) and analogues of this medication. For example, Candibiotic, Luan, Likain, Versatis, Helikain and Milgamma.

Basic information

The drug belongs to the group of local anesthetics, antiarrhythmic drugs. Available in the form of a clear solution for injection, without color and odor. The main drug in the composition is lidocaine hydrochloride in the amount of 100 and 20 mg per ml. By its chemical structure, the drug belongs to acetanilide derivatives. It has a pronounced local anesthetic and antiarrhythmic effect on the patient's body. The action occurs by reducing nerve conduction, which develops due to the blockade of channels in the nerve endings and fibers. The effect of lidocaine develops in a fairly short period and lasts up to 90 minutes. When used topically, the drug dilates blood vessels.

The components of the product are able to normalize the cell membrane, block sodium channels and increase the permeability of membranes for potassium ions. Accelerates repolarization in the ventricles of the drug "Lidocaine hydrochloride" in ampoules. The effect of the drug has been thoroughly studied over the years.

Indications and contraindications

The medication can be used in such cases:

1. Spinal, epidural, conduction, infiltration, thermal anesthesia.
2. Preventive measures of secondary ventricular fibrillation and repeated paraxisms of ventricular tachycardia.
3. Gastric arrhythmias that arose as a result of glycosidic intoxication.

Before starting therapy, it is worthwhile to carefully study all the information about the drug "Lidocaine hydrochloride." A Latin recipe might look like this: Rp .: Sol.Lidokaini 10% -2ml, Dtd N10 in amp.

Contraindications for the drug are as follows:

• Bradycardia
• Weakness of the sinus node.
• Ventricular blockade of the heart muscle.
• Heart failure in both acute and chronic stages.
• Cardiogenic shock.
• Low pressure.
• The period of gestation.
• Breastfeeding.
• An allergic reaction to the components of the product.

Not everyone can use Lidocaine hydrochloride as an anesthetic. The release form does not matter. Some patients may develop an allergy.

Dosage

For the above types of anesthesia, the drug is prescribed in a dose of 10 to 20 mg. The maximum daily allowance should not be more than 400 mg. In elderly people and patients with cirrhosis, the dose is set individually. As an antiarrhythmic medicine, the Lidocaine hydrochloride solution is administered intravenously. It is diluted with an isotonic agent until a concentration of 20 mg per 1 ml is obtained. Dripping the drug for 12 hours under the control of the pulse and ECG.

An overdose can provoke the development of the following symptoms:

• dizziness;
• nausea
• vomiting
• bradycardia;
• collapse;
• cramps.

When the well-being worsens, the patient is stopped administering the drug. Oxygenation is connected to him and symptomatic treatment is prescribed. In severe convulsions, diazepam is indicated. It is necessary to carefully observe the dosage for the drug "Lidocaine hydrochloride." Instructions for use contain detailed information about the drug.

Compatibility with other drug groups

Negative consequences are the interaction with the following medications “Digitoxin”, “Quinidine”, “Verapamil”, “Procainomyomas”, muscle relaxants, curare-like drugs. Co-administration can lead to increased effects of the drug. And also to the development of side effects when using Lidocaine Gyrochloride. A prescription is required. Without it, you will not be able to purchase the drug at the pharmacy. Next will be described the most popular substitutes for this tool.

Candibiotic

The medicine belongs to the group of drugs with antibacterial, anti-inflammatory, antifungal, and local anesthetic properties for local use. It is made in the form of ear drops. The main components in the composition are beclomethasone dipropionate, clotrimazole, lidocaine hydrochloride, chloramphenicol.

The medicine has the following actions:

• antifungal;
• bacteriostatic;
• anti-inflammatory;
• antiallergic;
• local anesthetic.

The drug “Candibiotic” has a wider range of effects compared to “Lidocaine hydrochloride”, which is mainly used for local anesthesia. Indications for its use are as follows:

1. Allergic and inflammatory pathologies of the ear.
2. External acute and diffuse otitis media.
3. Acute otitis media.
4. Chronic otitis media in the acute stage.
5. Postoperative intervention on the ear.

Candibiotic medicine is used only for ENT pathologies, unlike Lidocaine hydrochloride. Instructions for use will help to understand the features of the use of the medication. It also has contraindications: trauma of the eardrum, patient age up to 7 years, hypersensitivity to the components.

Dosage

The drug is instilled 4 or 5 drops into the external auditory meatus three times a day. Interaction with other agents has not been studied. In rare cases, an allergic reaction to the main components in the composition of the drug may occur. Recall that it includes beclomethasone dipropionate, clotrimazole, lidocaine hydrochloride, chloramphenicol. During pregnancy and lactation, the medicine is prescribed at the discretion of the doctor. It can be used only when the positive therapeutic effect for the mother outweighs the risk for the baby. You need to store the drug at a temperature of no more than 25 degrees, in a dark and inaccessible place for the kids. Candybiotic is available at the pharmacy with a prescription. It is not advisable to use drops for children under 6 years of age. During therapy, the correct dosage and doctor's recommendations must be observed.

The drug "Milgamma"

Available in the form of dragees and solution for injection. Refers to a complex of vitamins of group B. It is prescribed for pain relief. The composition of the drug includes thiamine hydrochloride, pyridoxine hydrochloride, cyanocobalamin, lidocaine.

The medication has a beneficial effect on the body in the treatment of ailments of the nervous system and motor apparatus. The main component enhances blood flow and improves the central nervous system.

Indications:

• Neuralgia of a different nature.
• Neuritis of the facial and trigeminal nerve.
• Osteochondrosis.

Contraindications:

• Decompensated heart failure.
• Minor age.
• Hypersensitivity to the elements in the composition.

Features of use

In case of severe pain, it is recommended to administer the drug every day for 10 days. Then, upon achieving a positive therapeutic effect, it is advisable to take the drug once or twice a week. The medicine is administered intramuscularly and deeply. Lidocaine hydrochloride (1%), which is part of the solution, relieves pain and burning in the patient at the site of pinched nerve between the vertebrae.

Gel "Luan"

The drug is used for superficial anesthesia. Available in the form of a transparent gel. The main element in the composition is lidocaine hydrochloride. The medicine is used for local exposure. It has an anesthetic effect. This is due to reversible inhibition of nerve endings on the surface of the skin and mucous membranes.

When is the drug used?

It is prescribed in order to conduct diagnostic and therapeutic endourethral and endoscopic procedures. Also, for local anesthesia, lidocaine hydrochloride in ampoules is prescribed. The action of the product is identical with the gel. The only difference is that the solution is administered intramuscularly or subcutaneously.

Contraindications:

1. The tendency to hemorrhoidal bleeding.
2. Trauma to the mucous membranes.
3. Hypersensitivity to substances in the composition of the drug.

Dosage

The tool is squeezed directly into the urethra. At the same time massage her back wall. Next, you need to clamp the urethra with a clamp and wait 10 minutes, and then proceed to diagnostic tests. The contents of one tube with the gel is enough for manipulation and persistent local anesthesia, thanks to a tool called lidocaine hydrochloride. Instructions for use describe when you can use the medicine. The annotation also indicates possible side effects.

Versatis

The medicine belongs to the group of local anesthetics. Available in the form of a patch of white or yellowish color. The main element in the composition of the drug is lidocaine hydrochloride in a dose of 700 mg. The size of the patch is 14x15 cm. The active ingredient is a derivative of acetamide. It has a membrane-stabilizing activity, causes a blockage of sodium channels of excitable membranes of neurons. It does not cause irritation on the skin.

Indications for use of the patch:

• pain relief for vertebral injuries;
• neuralgia that arose after a herpetic rash;
• myositis.

Local use of the patch may well become an alternative to the use of the drug "Lidocaine hydrochloride." Pain sensations disappear quickly enough. The drug is not prescribed for violation of the integrity of the skin, hypersensitivity to the main substance.

Dosage

The patch is for topical use. It is glued to the area that needs to be anesthetized. After contact with the product, wash your hands thoroughly. The medicine "Versatis" can be on the skin for up to 12 hours. Then you need to take a break for half a day. Then again you have to glue the patch. If hyperemia and burning appeared at the site of contact, then the system must be removed until the symptoms that have arisen disappear. After 20 minutes after gluing the patch, the patient will disappear pain.

Likain replaces lidocaine hydrochloride

The drug belongs to the group of antiarrhythmic drugs. It is a local anesthetic derived from acetanilide. It has membrane stabilizing activity. It causes all types of anesthesia. It blocks the sodium channels of the excited membranes of neurons and cardiomyocytes. The composition of the drug includes lidocaine hydrochloride monohydrate in a dose of 20 mg.

Indications:

• Treatment and prevention of ventricular arrhythmias.
• Myocardial infarction.
• Anesthesia
• Glycoside intoxication.
• Some types of anesthesia.
• Blockade of peripheral nerves and nodes.

Contraindications:

1. Shock.
2. Bleeding.
3. Severe pathology of the liver and kidneys.
4. Pregnancy.
5. Lactation.
6. Low pressure.
7. Bradycardia

Dosage

As an antiarrhythmic agent, the drug is administered intravenously at a dose of 2 mg per kg of patient body weight. The maximum rate for one application should not exceed 80 mg. From 2 to 4 mg per kg of body weight is administered intramuscularly. The interval between injections should be at least two hours.

For local anesthesia, the drug is administered in an individual dose for each patient, depending on the procedure and time for its completion. It is not recommended to take Likain together with the following drugs:

• Beta-blockers.
• "Phenobarbital."
• MAO inhibitors.
• "Suxamethonium chloride."
• Amiodarone.

Gelikain gel

The drug belongs to the class A antiarrhythmic drugs. It is a local anesthetic, a derivative of acetanilide. Causes all types of local anesthesia. It has membrane stabilizing activity. The composition of the drug includes lidocaine hydrochloride.

Indications

Gelikain gel is prescribed in such cases:

1. Treatment and prevention of ventricular arrhythmias.
2. Myocardial infarction.
3. Glycoside intoxication.
4. Blockade of peripheral nerves and nodes.
5. Local anesthesia in dentistry, obstetrics, surgery and gynecology.

Contraindications:

• Low pressure.
• Bradycardia
• Cardiogenic shock.
• Severe pathology of the liver and kidneys.
• Pregnancy.
• Breast-feeding.
• Hypersensitivity to the main component.

How to apply the medicine?

Gelikain gel is administered at the rate of 2 mg per 1 kg of body weight. The average single dose should not exceed 80 mg. The drug is administered intravenously for 5 minutes. Then, infusion is indicated for 12 hours. The medicine dissolves in an isotonic fluid.

Intramuscularly pricks at a dosage of 2 or 4 mg per 1 kg of patient body weight. Calculation of the medicine should be performed only by a doctor. Basically, the gel is well tolerated, but an allergic reaction may develop in the form of a rash and redness at the injection site. A prescription drug is sold in a pharmacy. You can not add a solution to the blood for transfusion. The medicine is stored at a temperature of no more than 25 degrees, in a dark, dry and out of reach of children. It is not recommended to drive vehicles and perform work associated with risk and danger during treatment. With caution, the drug is administered to patients after 65 years. It is advisable for patients with severe pathology of the liver and kidneys to abandon the use of the drug.

Side effects

Improper use of the drug can lead to the development of such symptoms:

• migraine;
• dizziness;
• tachycardia;
• pressure reduction;
• epigastric pain;
• nausea;
• sleep disturbance;
• excitement;
• pain in the spine;
• involuntary urination;
• respiratory depression until its cessation.

Before prescribing the drug, the doctor should thoroughly examine the patient's history, the presence of contraindications and an increased risk of an allergic reaction. During pregnancy and lactation, the medicine is administered only in emergency cases, when the benefit to the mother outweighs the risk to the baby.

Interaction with other groups of drugs

Joint administration with the following agents and substances is not recommended:

• barbiturates;
• beta-blockers;
• MAO inhibitors;
• amiodarone;
• propafenone;
• phenytoin;
• cimetidine.

It should be carefully injected into the forearm and neck. Especially if there was surgery in these places before. Also, patients during spinal and epidural anesthesia who have spinal deformity should refrain from using an anesthetic in this form. If a person has never been given Lidocaine hydrochloride before, it is recommended to do a subcutaneous test to exclude the presence of an allergic reaction.

Summarize

Experts note that in medical practice, drugs are often used, the active ingredient in which is lidocaine hydrochloride. This substance perfectly blocks nerve endings. Due to this, the patient does not feel pain during mild surgical interventions, as well as during diagnostic procedures. However, it is worth considering that the described drugs also have many contraindications. It is no coincidence that lidocaine hydrochloride is dispensed in pharmacies strictly according to a prescription.