One of the indicators of a woman's reproductive health is a stable menstrual cycle. If an imbalance occurs in the body, then your period may suddenly stop. Temporary amenorrhea is a sign of various pathologies - from simple overwork to hormonal failure in the body. Often, a gynecologist prescribes Duphaston according to the instructions for use in delaying menstruation. This drug helps to regulate and even restore the cycle.
What is Dufaston?
The drug belongs to the drug subgroup of hormonal agents. The main active ingredient is dydrogesterone synthesized artificially. This substance is a complete analogue of natural progesterone.
"Duphaston" is prescribed for various female pathologies that are accompanied by hormonal disorders. Usually, the appointment is performed after a full examination and tests, but in some cases, when visual signs indicate a lack of progesterone, the doctor may prescribe a woman to take the drug without detecting the level of hormones. However, he must first clarify whether Duphaston suppresses ovulation.
Therapeutic effect
The drug is preferred to other drugs, because under the influence of a natural analog of progesterone there is no change in thermogenesis, basal temperature. This indicator is used to identify the day of ovulation. When taking the drug, it can be measured, as before.
Another undoubted advantage is that Dufaston does not affect the metabolic processes occurring in the body and does not affect liver function. The main component (dydrogesterone) has a similar structure to natural progesterone. However, after conducting clinical trials, it was found that Duphaston does not cause negative effects that may occur while taking other modern synthetic progesterone-type medicines.
The drug also lacks androgenic, anabolic, cardioid, estrogenic effects. If the doctor prescribed Duphaston during the delay of menstruation, then the medicine has a positive effect on the level of lipids in the blood of the patient. The lack of androgenic properties suggests that after a long intake there will be no signs that occur when using other steroid hormones.
During oral administration, selective properties of dihydrotesterone on the endometrium in the uterus arise. This helps prevent hyperplasia and carcinogenesis. These diseases are often triggered by increased estrogen production. It must be borne in mind that during the administration of Duphaston there is no contraceptive effect.
When prescribing the drug, the selective effect that it has on the progestin receptors of the uterine mucosa is taken into account. Due to its similarity with the natural hormone, the level of excitability of the myometrium is significantly reduced along with the contractile activity of the uterus. Before you find out if Duphaston suppresses ovulation, you need to consider that it has an individual effect on the body. Therefore, it is difficult to unambiguously predict what the consequences and side effects will be.
Indications
The main reason the doctor prescribes the use of Duphaston is a critical lack of the hormone progesterone. This pathology can provoke the following diseases and conditions:
- endometriosis - the occurrence of foci of the endometrium outside the uterus;
- the threat of miscarriage due to low endogenous progesterone;
- primary and secondary infertility, which appeared due to luteal insufficiency (decreased functional activity of the corpus luteum of the ovary);
- premenstrual syndrome associated with severe pain, mood changes and other functional changes in the female body;
- secondary amenorrhea - the absence of menstruation that appeared after a disease of the reproductive system;
- dysmenorrhea - a violation of regular menstruation;
- uterine bleeding of various etiologies.
In addition, the drug can be prescribed by a gynecologist if hormone replacement therapy is needed. It is introduced when it is necessary to neutralize the increased effect of the hormone estrogen on the endometrium. Often, an effect such as natural or induced postmenopause occurs after surgery, therefore hormone treatment is required.
Contraindications
Consulting a doctor before taking the drug is extremely necessary. A medical professional will help determine the exact dosage. He will be able to determine if there are contraindications for taking the drug. Do not use Dufaston if there are the following pathologies:
- hypersensitivity to dihydrotesterone;
- hepatosis - severe liver disease;
- Rotor and Dubin-Johnson syndrome.
If the drug has never been taken before, it is recommended to start the course with a minimum dosage. Then, in the presence of allergic intolerance, negative consequences can be avoided.
Side effects
When choosing the wrong dosage or if you are allergic to the components of Dufaston, various side effects may appear. They affect different organs and systems. The main ones include:
- pain in the liver;
- disturbances in the work of the gallbladder;
- yellowing of the skin;
- paroxysmal headache;
- breast hypersensitivity;
- hives;
- swelling;
- uterine bleeding;
- hemolytic anemia, leading to increased destruction of red blood cells.
If uterine bleeding begins during treatment, you should immediately go to the hospital. Also, with other side effects, the doctor should adjust the dosage of Duphaston. Usually, a slight increase in the dose will stop undesirable bleeding and decrease the sensitivity of the mammary glands.
As for allergic reactions, these manifestations should immediately alert, because they speak of hypersensitivity to the main component. In rare cases, an effect such as Quincke's edema and anaphylactic shock was observed. When these signs appear, you must stop taking "Duphaston" and consult a doctor about the selection of an analogue. Such side effects are the reason for refusing the drug.
Mechanism of action
Often women with an irregular cycle are prescribed Duphaston. The mechanism of action of the drug is simple. Synthetic hormone acts as natural progesterone. Therefore, with a lack of it in the body of a woman, the substance will contribute to the proper development of the inner layers of the uterus. If these membranes, called endometrium, have a normal thickness, the patient will be able to conceive and carry a healthy child without problems. Therefore, the long-awaited pregnancy after the abolition of "Duphaston" is more likely.
During the development of the phases of the menstrual cycle, the endometrial membrane begins to grow and thicken. This mechanism is laid down by nature to better attach a fertilized egg to the uterine wall. If the whole process went without pathologies, then a high level of the hormone is necessary so that the endometrium is maintained in a normal state. When the embryo could not attach to the uterine wall, the percentage of progesterone in the blood begins to decline, and the endometrium comes out with bloody secretions.
Effect on Ovulation
Most doctors answer the question of women, suppresses Duphaston ovulation or not, give a negative answer. The drug, prescribed in the correct dosage, cannot have a negative effect on the production of the egg. However, it should be borne in mind that it is not recommended to take more than 30 mg of the drug daily. This dose of the hormone under the influence of various factors can adversely affect reproductive function.
To test whether Dufaston suppresses ovulation or not, a scientific experiment was conducted. Doctors monitored several women. They studied how they develop the process of egg maturation. If the patient had a luteal phase insufficiency, into which the egg leaves the follicle, she was prescribed this drug. During the next cycle continued to take "Duphaston." An ovulation test and an ultrasound machine monitored how the egg leaves the follicle after maturation. In 99% of cases, the process occurred without pathologies and ensured successful implantation. Therefore, the question of whether there can be ovulation after Dufaston, the doctor will only answer in the affirmative.
Mode of application
"Dufaston" refers to drugs that can be taken both before and after meals. One tablet contains 10 mg of dydrogesterone. When prescribing, the doctor takes into account all the factors that influenced the development of pathologies, so an individual dose is prescribed for each patient.
There is a standard instruction for the use of "Duphaston" for delayed menstruation. The drug in this case is prescribed one tablet 2 times a day. Reception of tablets is carried out from 11 to 25 day of a cycle. If a woman has amenorrhea, then treatment is prescribed according to the same scheme, while taking estrogenic medications. It should be borne in mind that during the "Dufaston" therapy it is not recommended to use any alcoholic beverages.
When the cycle will recover
Many patients are interested in how quickly menstruation will improve after Duphaston, how many days will come menstruation. Doctors advise not to rush to stop taking the medicine - the duration of therapy can be completely different. The recommended course duration is from 1 to 5 months. If the disorders are due to small functional solutions, everything is restored already on the third day after the drug is stopped.
Sometimes menstruation can occur even before the end of the course of treatment. However, in this case, it is recommended to continue taking it without deviating from the scheme prescribed by the doctor. This is necessary so that the hormonal background of a woman normalizes completely.
Reviews
Subject to the prescribed dosage and the rules for admission, the patient notices the relationship between Duphaston and ovulation. The reviews left about the medicine prescribed in the absence of menstruation are positive. The drug is effective in most cases. Women write that they were interested in advance with the gynecologist whether Duphaston suppresses ovulation. Separately, patients note the affordable price of the drug, which is available to many categories of the population.
Output
Despite the fact that the medicine has only one active ingredient, Dufaston copes with various problems of the female body, helping to conceive and endure a healthy child. Doctors who prescribe the drug recommend that you do not self-prescribe and go to the clinic so that the dosage is correctly selected.