One of the urgent problems for some people is overweight. Often, pathology occurs against the background of metabolic disorders in the body, but there may be other reasons. Depending on the degree of development of the disease, a cure for obesity is prescribed, which helps to reduce body weight to normal levels. Let us consider in more detail the most effective means to help cope with overweight.
Causes of Obesity
Obesity is a condition of the body in which an excess of body fat appears in the tissues, organs and subcutaneous tissue. In addition to psychophysical problems, pathology causes changes in the functioning of internal systems and organs. According to statistics, women are twice as obese as males.
The main reason for the appearance of extra pounds is overeating. Excess calories that enter the body along with food do not have time to be used up and are deposited in the subcutaneous tissue, on the internal organs. A gradual increase in these fat depots leads to weight gain.
The following factors also apply to the development of obesity:
- sedentary lifestyle;
- eating disorders (eating a lot of carbohydrates, eating before bedtime);
- depression, stress, insomnia;
- endocrine disorders;
- digestive tract dysfunction;
- violation of the hypothalamic-pituitary function;
- the use of certain medications (hormonal drugs, antidepressants);
- hormonal changes (menopause, pregnancy);
- violation of metabolic processes.
When should I start taking drugs?
Body mass index is the main indicator for determining the stage of obesity. To find out the BMI values, you need to make simple calculations: divide a person’s weight by height (in meters), taken in a square. For example, with a mass of 75 kg and a height of 168 cm, the index will be: 75 / (1.68 × 1.68). After counting, we get the index value of 26.57. WHO recommends interpreting the results as follows:
- ≤ 16 - acute lack of body weight ;
- 16-18.5 - lack of weight;
- 18.5-25 - normal weight;
- 25-30 - there is a slight excess of mass;
- 30-35 - the first degree of obesity;
- 35-40 - the second stage of the disease;
- 40-50 - the third degree of obesity;
- ≥ 50 - overcoating.
After determining the stage of development of the pathology and conducting the diagnosis, the specialist should choose drugs for obesity. The list of drugs that will help in this situation is quite large. Some of them are dispensed strictly according to a doctor’s prescription, because they have many contraindications and side effects. Specialists try to resort to the help of drug therapy only if the body mass index is more than 30.
How do medicines work?
Medications for the treatment of obesity have different mechanisms of action, but they have one goal - to reduce and control body weight. Depending on the principle of work, the following categories of medicines are distinguished:
- Anorexigenic drugs are drugs that affect the center of saturation in the brain and inhibit appetite. Thanks to their action, the patient begins to eat less food. In addition to being well tolerated, this group of drugs also helps establish a nutritional culture.
- Fat burners - block the absorption of fat, thereby helping to remove it from the body. They are divided into several groups: thermogenetics (increase the heat production of the body), lipotropics (stimulate the liver), dietary supplements (increase the production of bile) and hormonal drugs (affect the functioning of the thyroid gland).
- Laxatives - accelerate the process of excretion of intestinal contents, but do not affect body weight.
- Diuretic drugs - remove excess fluid from the body and do not affect subcutaneous fat.
Obesity Cures: List
The best medications for treating obesity are those that have been prescribed by your doctor individually. The specialist selects the drug depending on the causes of overweight and the presence of concomitant ailments. Self-medication in this case can be extremely dangerous.
Obesity drugs, the list of which is presented below, are prescribed only in those cases when following a strict diet and exercise did not have the desired effect. Potent drugs for obesity include:
- Ortosen.
- "Xenical."
- Meridia.
- Orlistat.
- Reduxin.
- "Liraglutide."
- Sibutramine.
- Listata.
- Lindax.
- Goldline.
- "Laminin."
Each of the medicines has both advantages and disadvantages, which you must be familiar with before starting treatment.
"Sibutramine" with excess weight
Sibutramine is an effective anorexigenic cure for obesity. Available in the form of capsules and tablets that contain sibutramine hydrochloride monohydrate. The active ingredient enhances thermogenesis and stimulates the formation of active metabolites that inhibit the reuptake of norepinephrine and serotonin.
As part of the complex treatment, Sibutramin is taken for alimentary obesity in patients with a body mass index of more than 30. It is also allowed to use the medication for obesity with diabetes mellitus (non-insulin-dependent).
Contraindications
With high sensitivity to constituent components, serious eating disorders, mental disorders, arterial hypertension, severe pathologies of the liver and kidneys, pregnancy and lactation, angle-closure glaucoma, heart and vascular diseases, this medicine for obesity is not used. A new agent should only be prescribed by a specialist.
Patient Reviews
Many overweight people take Sibutramine. The drug has proven itself on the positive side and really helps fight obesity. If the doctor's recommendations are followed, the pills practically do not have side effects. However, during the treatment period, symptoms such as dry mouth, anxiety, anxiety, headaches, constipation, tachycardia, arterial hypertension may still occur.
"Lindax": a description of the drug
According to experts, the best medications for obesity are those that are prescribed individually and are selected depending on the needs of the patient. The drug “Lindaxa” (Czech Republic) has good therapeutic properties. The therapeutic effect is provided by the substance sibutramine.
Anorectic affects the centers responsible for food saturation. Biotransformation of the active component occurs in the liver, where active metabolites are formed.
The dosage of “Lindaxa” is selected individually and depends on the degree of obesity. The recommended starting dose is 10 mg. The medicine can be taken without regard to food. Increase the dosage to 15 mg in the absence of a visible therapeutic effect. The duration of therapy is from 3 to 12 months.
The medication has the same contraindications as the “Sibutramine” remedy. Frequent side effects that occur while taking Lindaxa include tachycardia, dry mouth, thirst, dizziness, and insomnia.
Reviews about the drug "Liraglutid"
The hypoglycemic anti-obesity medicine “Liraglutide” is used to treat the second type of diabetes and chronic obesity. The tool is permitted in many countries only in the form of the drug "Victoza" (Denmark). Another brand name of the drug - “Saksenda” appeared on the pharmaceutical market in 2015 and positions itself as a drug that helps fight overweight in adult patients.
"Liraglutide" is a synthetic copy of glucagon-like peptide-1, which is produced in the human intestines and actively acts on the pancreas and stimulates the production of insulin. The body is unable to distinguish between a natural and externally introduced enzyme. The use of the drug allows you to gradually establish the natural production of insulin and reduce sugar levels. This, in turn, normalizes the absorption of nutrients from consumed foods.
Patient reviews confirm the presence of a pronounced therapeutic effect in the drug. The tool is quite convenient to use, because it has the shape of a pen-syringe, on which divisions are applied, allowing you to accurately calculate the dosage. The medicine is administered to the shoulder, thigh or abdomen. This drug for obesity in pharmacies can be purchased only with a prescription.
The cost of drugs based on liraglutide ranges from 9,500 (Victoza, 2 syringes) to 27,000 rubles (Saksenda, 5 syringes). Specialists rarely use these medicines to treat patients with diabetes and obesity due to the high cost.
Destination Features
It is strictly forbidden to take hypoglycemic drugs for weight loss in obesity without a doctor’s prescription! “Liraglutid”, “Saksenda” and “Victoza” cannot be used for type 1 diabetes, severe liver and kidney pathologies, pregnancy, inflammatory processes in the intestines, heart failure (types 3 and 4), thyroid neoplasms.
Treatment with the drug should be continued only if the patient managed to lose at least 5% of his weight in 16 weeks. If such results cannot be achieved, it is necessary to choose other drugs to get rid of extra pounds.
The drug "Orlistat"
Orlistat tablets have a peripheral effect and help to lose extra pounds without harm to the body. The main objective of the medication is to block the process of absorption and digestion of fats. A cure for obesity can lower cholesterol and glucose, which allows it to be used in the treatment of diabetes.
The drug "Orlistat" is an inhibitor of gastrointestinal lipases. Due to this pharmacological action, the penetration of triglycerides into the blood is blocked, a deficiency of energy is manifested, causing mobilization of body fat from the depot.
The medication should not be used for hypersensitivity, nephrolithiasis, cholestasis, hyperoxaluria, pregnancy and lactation. Orlistat is not prescribed for children under 12 years of age and people suffering from chronic malabsorption syndrome.
What do doctors and patients say?
Most reviews of the drug contain positive recommendations. Many patients were able to lose about 10 kg of excess weight in 8-12 months with the help of this medication for obesity. Reviews of experts saying that Orlistat is one of the few drugs that practically do not cause side effects. Occasionally, cases are recorded when the stool and the digestive tract are disturbed, and frequent urges to defecate appear.
Means "Xenical"
Another medicine based on orlistat is Xenical. A medicine is produced in Switzerland, which significantly affects its cost. You can buy a cure for obesity for 2300-2700 rubles. Xenical is available in the form of gelatin capsules with a turquoise color.
According to the instructions, the drug can act on enzymes in the digestive tract, which contribute to the digestion and absorption of fats, i.e. lipase. A significant advantage of Xenical is its minimal systemic effect. The drug can be taken for a sufficiently long time for patients who have problems with overweight and high glucose levels. In addition to taking the medication, you will need to adhere to a hypocaloric diet and engage in moderate physical activity.
Take "Xenical" three times a day, one capsule (120 mg) with meals. The duration of treatment and the need to adjust the daily dosage is determined only individually.
Side effects
The manufacturer refers to urgent side effects urgent urges to defecate, loose stools, flatulence, abdominal discomfort. To avoid such unpleasant phenomena, it is necessary to limit the use of fatty foods. Only 2% of patients suffering from diabetes showed a hypoglycemic state. An allergy to the active substance in the form of urticaria, itching, redness of the skin is possible. More serious cases are rare: bronchospasm, angioedema.
Obesity and Overweight
Fatty hepatosis is a serious liver disease. Most often, the disease affects people with metabolic disorders, overweight, bad habits, protein deficiency, hypovitaminosis. Symptoms at the initial stage of the disease usually do not appear, and the patient seeks medical help when the situation is running. The treatment technique is selected after laboratory tests, ultrasound of the liver.
To prescribe drug therapy, you should consult a gastroenterologist or hepatologist. A medicine for liver obesity is prescribed in combination with preventive measures. If the cause of the disease is overweight, you must always adhere to a diet (table number 5), completely eliminate junk food from the diet and engage in physical activity. Danger to the body is a sharp weight loss (more than 700 g per week), which can cause the progression of the pathological process.
Drug treatment
What medications for obesity of the liver will help cope with the disease? First of all, the patient will be prescribed drugs that normalize the work of the body. Hepatoprotectors, drugs that stimulate the functionality of liver cells and protect it from the negative effects of harmful food, toxins, and some medications, have regenerative properties . This category of drugs includes:
- Heptral.
- Essential Forte.
- Essliver.
- Liv-52.
- "Carsil."
In the treatment of fatty hepatosis, you will need to lower cholesterol. The drugs from the group of statins will cope with this task: Atoris, Liprimar, Krestor. In addition, you will need to take antioxidant agents and vitamin complexes.
Heptral: instruction
Heptral "is a French medicine for liver obesity. The name of the active substance is ademeteonin. In one tablet it contains 400 mg. The same dosage of the active component is also available in ampoules, with a volume of 5 ml. Lyophilisate for solution preparation is suitable for both intramuscular and intravenous administration to patients.
The drug has a detoxifying, choleretic, hepatoprotective, antioxidant and cholekinetic effect on the body. In addition, the manufacturer claims that the active substance has neuroprotective, antidepressant and anti-fibrosing properties. The medication is able to enhance the secretion of bile and make up for the lack of adenosylmethionine (coenzyme).
Prescribe the drug for fatty hepatosis, chronic hepatitis, intoxication of the liver, encephalopathy, angiocholitis. Genetic disorders affecting the adenosylmethionine cycle and tearing out homocystinuria or hyperhomocysteinemia are contraindications for the use of Heptral.
Description of the drug "Liv-52"
The medicine for liver obesity "Liv-52" is a hepatoprotector based on plant components. The active substances used are chicory seeds, prickly caper roots, yarrow, cassia seeds, tamarix and black nightshade. The listed components are specially treated with steam from a mixture of other plant extracts.
The drug is available in the form of tablets and drops of a dark brown color for oral use. The combined herbal medicine has a choleretic, hepatoprotective, anti-inflammatory and antioxidant effect. With its help, it is possible to block the development of degenerative and fibrotic changes, activate intracellular metabolic processes and restore hepatocytes.
Indications for the appointment of a herbal medicine are such pathologies as fatty hepatosis, hepatitis of various origins, cirrhosis. You can take Liv-52 as a cure for obesity. In pharmacies, the average cost of a medication is 380-450 rubles.
A medication in the form of drops can be prescribed for preventive and therapeutic purposes for children over 2 years old. It is forbidden to use "Liv-52" during pregnancy and lactation, as well as with increased sensitivity to the components of the product.