What is Galazolin and what are nasal drops used for? Most will not be able to give an answer. "Galazolin" is an effective nasal remedy for the common cold. Its action is aimed at narrowing the vessels of the nasal mucosa, relieving swelling and eliminating the common cold with its consequences. After application, the drops begin to act in just a few minutes, subsequently the result remains almost half a day. The tool does not negatively affect the functioning of the nose.
The drug refers to imidazoline derivatives, the action of which leads to a narrowing of arterial vessels. As a result, the patency of the nasal passages is restored. The medicine begins to act as soon as ten minutes after application. The effect lasts from eight to twelve hours. If the dosage is observed correctly and the medicine is not used for other purposes, no side effects are observed. Let’s try to figure out why Galazolin is used in drops by adults and children.
Structure
The main component in the composition is xylometazoline hydrochloride. In addition to it, additional auxiliary substances also enter, such as sodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate monohydrate, sodium chloride, disodium edetate, benzalkonium chloride 50%, sorbitol, purified water.
Xylometazoline - a drug, alpha-adrenostimulator. The structure is close to naphazoline. Xylometazoline is on the list of essential substances. It is used as a means to relieve symptoms, helps to eliminate nasal congestion, otitis media. Manufacturers limit the continuous use of the drug for a week period, with an interval of 6 hours between doses to avoid side effects.
Indications
So why is Galazolin needed? It is recommended for use in acute rhinitis of various forms, acute otitis media, as well as in acute or chronic sinusitis.
Contraindications
After you figured out why Galazolin is needed, it is worth saying that it is undesirable to use drops in the presence of at least one of the following points:
- hypersensitivity to components;
- atrophic inflammation of the nasal mucosa;
- increased intraocular pressure;
- tachycardia;
- diabetes;
- after operations with a section of the dura mater;
- acute coronary diseases, hyperthyroidism, glaucoma, coronary asthma;
- joint treatment with MAO inhibitors and after their use after a couple of weeks.
Drug Interactions
It is forbidden to use Galazolin drops (for children and adults) simultaneously with MAO inhibitors and tricyclic antidepressants. Also, the drug should not be taken in conjunction with other sympathomimetic agents due to their simultaneous exposure.
The main component - xylometazoline, is able to affect the functioning of some antihypertensive drugs, these include beta-blockers and some antidepressants (tricyclic or tetracyclic). Joint use with beta-adrenergic receptors can provoke a bronchial spasm or a decrease in blood pressure.
special instructions
"Galazolin" for the nose 0.05% is prohibited for use by babies younger than 12 months.
"Galazolin" 0.1% is not recommended for children under 12 years of age.
The drug should be prescribed with extreme caution to people with severe hypersensitivity to adrenergic agonists, the symptoms of which are manifested in insomnia, trembling, dizziness, impaired heartbeat and hypertension.
It is not recommended to use drops for people with chronic or vasomotor rhinitis, since they can use them for more than 5 days.
It is impossible to use "Galazolin" for longer than the indicated period, as the result may be secondary expansion of blood vessels, which in the end leads to drug rhinitis.
The delayed release of norepinephrine from the nerve endings, through the excitation of alpha² receptors, provokes such a disease.
It is necessary to use drops with caution to people with circulatory diseases, diabetes, problems with the prostate gland and thyroid disease.
Do not use doses higher than recommended, especially for children and the elderly.
In the case of prolonged use of Galazolin, undesirable consequences, such as irritation of the mucous membrane, can occur.
As for the administration of the drug during the management of transport mechanisms, the drops do not adversely affect the work. The main thing is to take it correctly taking into account all the described dosages, also adhering to the recommendations.
If the dose is exceeded or reception is disturbed, side effects may occur that adversely affect well-being and overall health.
Use during pregnancy and lactation
According to the instructions, drops of "Galazolin" is not recommended for use during pregnancy. As for the lactation period, the effect of drops on milk has not been established, therefore it is possible to take drops during breastfeeding, but with extreme caution and with the permission of the doctor.
Instruction manual
The content of xylometazoline hydrochloride in one drop is 0.025 mg.
Babies from 4 months to 2 years old are allowed to use a drop of “Galazolin” in each nostril. The interval between applications is 8-12 hours.
"Galazolin" 0.05% is recommended for children from 2 to 6 years old, one / two drops per nostril. Use is allowed once or twice (if necessary) per day.
"Galazolin" 0.1% is prescribed to children over 6 years of age and adults 2-3 drops in the nostril. It is allowed to apply from 2 to 3 times a day.
It is worth noting that drops are not allowed to be used more than three times a day.
It is also very important not to increase the indicated dosage in order to avoid unpleasant symptoms. The course of treatment should not exceed 5 days without the recommendation of a specialist. The maximum allowed time is 14 days.
Overdose
An increased dose can lead to headaches and dizziness, lowering temperature, sweating, bradycardia, hypertension, seizures and coma. Do not forget that children are especially sensitive to the action of the drug than adults.
When using more than 0.2 mg / kg, heart palpitations, increased fatigue, and increased blood pressure may occur.
In addition, nausea, cyanosis, dilated / narrowed pupils, sweating, tachycardia, arrhythmia, asystole, decreased pressure, pulmonary edema, impaired breathing and circulation can be observed.
An overdose of the drug (especially in children) can adversely affect the central nervous system and its work. Become the cause of coma, high blood pressure, convulsions.
In case of an overdose, you should immediately contact a specialist and in no case do self-medication. It is important to seek help within an hour after improper administration or dosage violations.
Application Tips
Before use, the nasal passages should be cleaned.
For children under 2 years of age, generally accepted clinical standards are not indicated (use only 0.5% solution).
It is forbidden to use drops for a long time, for example, with chronic rhinitis.
In case of colds, in cases where crusts form in the nose, it is preferable to prescribe a gel preparation.
Missed dose: use immediately within 1 hour, do not use after 1 hour; do not double the dose.
Shelf life
Drops "Galazolin" 0.05% and 0.1% are suitable 4 years from the date of issue. Store at 25 ° C out of the reach of children. "Galazolin" can be purchased in cardboard packaging along with a leaflet with detailed information about the drug.
Galazolin: analogues
Consider the most suitable drugs in action, which include xylometazoline. This substance activates alpha adrenergic receptors. With local use, it is practically not absorbed in any way, for this reason the concentration in the blood is very low (analytically not determined). When applied to the mucous membranes, it causes a decrease in blood vessels, lowering local hyperemia and edema. With rhinitis, it simplifies nasal breathing. The effect begins in a couple of minutes and lasts for a couple of hours.
- "Xylometazoline";
- Rinorus
- "Rinostop";
- "Asterisk NOZ";
- Xylen.
Analogues will also include products containing alpha-adrenergic agonists - pharmaceutical substances that stimulate alpha-adrenergic receptors. Norepinephrine induces arteriole alpha-adrenergic receptors, increases their activity, increases blood pressure, and reduces renal and hepatic blood flow. It has a weak effect on beta-adrenergic receptors of the heart, in therapeutic doses it does not significantly affect the frequency and strength of heart contractions.
- "Naphthyzine";
- Sanorin
- Adrianol;
- "Tizin";
- "Nazol."
Other popular analogues of similar action:
- "For carrying" (drops, spray);
- "Imidine N";
- Otrivin;
- "Xilo Nazal."
Precautions
The bottle with drops is intended for individual use by one person. Such measures are needed to prevent transmission of infections between people.
The product can not be used for babies younger than 3 months. Also, children should not take the drug without the permission of a specialist.
Reviews
Excellent vasoconstrictor, very effective in use due to the main component - xylometazoline. Drops cope with their appointment at 100%, actively fight with a runny nose and its consequences. Affordable price, which is fully consistent with quality. Large production and release of the drug, it can be purchased everywhere. A universal remedy that is suitable for any age, is sold without a prescription, it is allowed to use even the smallest.