"Celestoderm" with Garamycin - what is this medicine and for what diseases is it used? In our article you will find answers to these questions. Here, detailed instructions for the use of this therapeutic agent are given, contraindications, side effects of the drug are described, as well as some reviews of people who have tried the effects of this medicine on themselves.
Composition and form of release
The drug "Celestoderm-B" with Garamycin is available in two forms:
- Ointment of white color, homogeneous, not containing any visible coarse particles, with a soft consistency. It consists of betamethasone valerate, gentamicin and such auxiliary substances as soft paraffin and paraffin in liquid form.
- Cream of white color, soft consistency, homogeneous. It contains betamethasone, the antibiotic gentamicin and auxiliary substances: soft and liquid paraffin, cetostearyl alcohol, phosphoric acid, cetostearyl ether, sodium dihydrogen phosphate dihydrate, chlorocresol, sodium hydroxide, and purified water.
In pharmacies you can buy "Celestoderm" with Garamycin - 0.1% ointment - tubes of 15 and 30 grams. Cream 0.1% is also available in tubes of 15 and 30 grams. Both are intended for outdoor use only.
Mechanism of action
How does the external preparation "Celestoderm-B" work? The therapeutic effect is achieved thanks to the betamethasone valerate included in its composition. This substance is a glucocorticosteroid (GCS) and gentamicin, a broad-spectrum antibiotic.
Betamethasone has an active anti-allergic and anti-inflammatory effect, slows down the release of inflammatory mediators and cytokines, limits the rate of arachidonic acid metabolism, induces the effect of lipocortins, and reduces vascular permeability.
Gentamicin, a broad-spectrum antibiotic, is active when applied topically against the vast majority of pathogenic microorganisms (Staphylococcus aureus, streptococci, gram-negative bacteria, etc.).
The drug, due to its microdispersed composition, easily and quickly penetrates the skin and begins to act actively. The shelf life of the drug is large - 5 years. After this period, the drug can not be used.
How to store
The official instructions indicate only that you need to store the tubes with the drug at a temperature of no more than 25 degrees.
Indications for use
What diseases is prescribed the drug Celestoderm? Indications for use are as follows:
- neurodermatitis;
- various types of eczema (coin-like, atonic, pediatric);
- contact dermatitis;
- seborrheic dermatitis;
- exfoliative dermatitis;
- sunny dermatitis ;
- radiation dermatitis;
- psoriasis;
- diaper rash treatment;
- senile and anogenital itching.
Cream and ointment "Celestoderm" with Garamycin are successfully used as an external therapeutic agent for skin diseases that respond to GCS (glucocorticosteroid) therapy, as well as in the development of a secondary infection provoked by microorganisms sensitive to gentamicin.
Detailed instructions for use
And now we will tell you how to apply Celestoderm ointment with Garamycin correctly. The instruction for the drug explains everything very clearly. An ointment or cream is applied in an even layer to problem areas on the skin from two to six times a day (the frequency depends on the severity of the disease), then rubbed into the skin surface with careful movements. In mild cases, it is enough to apply the product on the skin only once a day. For patients with damage to the skin of the face and children, the general course of treatment with the drug should be no more than five days.
Side effects
The drug "Celestoderm-V" with Garamycin, the price of which is quite affordable, is very popular among the population. However, this tool can be used only for really serious indications. Both ointment and cream can have many side effects. Here is a list of them:
- Extreme dry skin, burning sensation.
- Skin irritation in the form of erythema and itching.
- Folliculitis.
- Skin acne or acne.
- Hypertrichosis.
- Hypopigmentation.
- Maceration of the skin.
- Contact allergic dermatitis.
- Perioral dermatitis.
- Skin atrophy.
- Secondary infection
- Prickly heat.
- Striae.
- The development of the so-called systemic side effects (hyperglycemia, osteoporosis, ulceration in the gastrointestinal mucosa, increased pressure, insomnia and agitation, swelling, menstrual irregularities in women, exacerbation of focal infections, weight gain, etc.), which are characteristic of long-term treatment with glucocorticosteroids , especially if the drug is applied to sufficiently large areas of the body.
- In children, there may be an inhibition of the functions of the pituitary-hypothalamic-adrenal system, growth retardation, slower weight gain, Cushing's syndrome, as well as increased pressure (intracranial).
Analogs of "Celestoderm" with Garamycin can cause the same many side effects.
Contraindications
It is not recommended to take "Celestoderm-B" in the following conditions:
- lactation period;
- post-vaccination period and with the manifestation of skin reactions after vaccination;
- hypersensitivity to the drug components specified in the instructions;
- cutaneous tuberculosis;
- with skin manifestations of syphilis;
- fungal lesions of the skin;
- chickenpox;
- rashes of herpes;
- the age of the child is up to 6 months;
- pregnancy (with prolonged treatment of a large area of the skin).
Is it possible to use "Celestoderm" during pregnancy and during breastfeeding?
Is it possible for pregnant women and breast-feeding mothers to use Celestoderm ointment with Garamycin? The instructions attached to the tool indicate that at the moment there is no reliable evidence of the safety of the use of GCS (glucocorticosteroids) in this category of patients.
Therefore, the appointment of both Celestoderm and its analogues during pregnancy and lactation is permissible only if the patient’s benefit far exceeds the possible risks of negative effects of the drug’s active substances on the baby. In any case, during pregnancy it is unacceptable to use glucocorticosteroids for a long time and in large dosages.
Is it possible to prescribe the drug to children
It is known that children are more susceptible than adults to the action of various drugs, including such a drug as Celestoderm. The use of glucocorticosteroids by small patients is possible only from the age of six months and not before.
Due to the fact that in babies there is a higher absorption of the drug due to the large ratio of body weight to its surface area, as well as a higher susceptibility to the drug, inhibition of the functions of the hypothalamus and adrenal glands can occur in the child's body. Therefore, the use of external agents with glucocorticosteroids for the treatment of children should be done with caution, only after consulting a specialist and under his subsequent supervision.
special instructions
When buying the drug "Celestoderm" with Garamycin, one must take into account that the use of ointment is indicated for skin lesions on the background of psoriasis or dry eczema, but the cream is used for oily skin diseases or for soaking dermatitis and eczema.
If the drug is used by the patient for two weeks, and the healing effect is absent, this is an occasion to stop further use of the drug and visit the attending physician in order to clarify the diagnosis and review the treatment regimen. "Celestoderm-B" should be discontinued in case of skin irritation or sensitization, these symptoms are also an occasion to contact a dermatologist.
With prolonged use of the drug, side effects characteristic of glucocorticosteroids may occur, especially in children. Systemic absorption of corticosteroids with local long-term treatment of large areas of the skin or with the use of occlusive dressings can increase, especially often in pediatric patients.
If there are skin cracks, then with prolonged treatment of large areas of the body, gentamicin absorption may increase. In such cases, there is the possibility of developing unwanted side effects typical of the systemic use of gentamicin, especially in children.
Occasionally, local use of antibiotics can provoke the growth of microflora insensitive to them, including fungal. In such cases, treatment is discontinued and appropriate therapy is prescribed. If the drug is applied to pink or ordinary acne, then an exacerbation of the disease is not excluded.
"Celestoderm" with haramycin (ointment and cream) is intended exclusively for external use and is not used to treat ophthalmic diseases. It is necessary to carefully protect the mucous membrane of the eyes from getting cream or ointment "Celestoderm-B" on it.
Interaction with other drugs
The external drug Celestoderm with Garamycin applied to the skin practically does not enter the bloodstream (is not absorbed) and does not show systemic suggestion. Therefore, patients may not be afraid of the negative interaction of Celestoderm with other drugs taken by them.
Analogs
This chapter presents analogues. Celestoderm with Garamycin can be replaced with the following drugs:
- Akriderm;
- Betamethasone
- Beloderm;
- "Betamethasone sodium phosphate" ;
- Betazone
- Betazone Valerate;
- Betliben
- "Betamethasone dipropionate";
- Betnovate
- Cuteride;
- Diproslan;
- Flostretorn;
- Celeston.
"Celestoderm-V" with Garamycin: reviews
I must say that opinions on the drug are not unambiguous. As with most medicines, someone praises him, while someone scolds him. But, at least, getting acquainted with the experience of people to whom they willingly share, you can draw useful conclusions for yourself and avoid some mistakes when using the tool.
What do people like Celestoderm-V with Garamycin like? Reviews of many claim that it helps a lot with difficult diseases like eczema and neurodermatitis. Some former patients say that with the help of the drug “Celestoderm-B” it is possible to get rid of exacerbation of neurodermatitis in 5-7 days. And this, it is worth noting, is a very good result. At the same time, those who used this tool are advised to conduct treatment in combination with taking B vitamins. Moreover, the sooner the application is started, the more effective the results will be.
Some say that Celestoderm is the only remedy that helps fight eczema on the hands. Reviews indicate that even more expensive drugs are powerless in the fight against the problem, and the medicine "Celestoderm", the price of which is not at all sky-high, successfully copes with it.
But there are also negative reviews. It is said that the ointment in question not only does not help, but also causes severe hair loss on the head (when trying to cure dandruff on your own). But such situations are only confirmation that using strong medicines without consulting a doctor is not worth it.
Those people who have positive experience with the drug praise it very much, but almost all warn that it is best to use it with antihistamines (for example, Diazolin) in order to avoid allergic reactions. And in the event that the doctor prescribes the ointment or cream, then he also prescribes an additional anti-allergic agent.
Drug price
Our article is coming to an end, we managed to present a lot of information in it, perhaps we didn’t say just one thing: what is the cost of Celestoderm? The price today ranges from 200-350 rubles. for one tube. When buying, be sure to ask the pharmacist who the manufacturer of the drug is. To date, the ointment and cream "Celestodrem-V" produced in Russia and Belgium are supplied to the pharmacy network. Of course, domestic drugs are much cheaper than imported ones - this must be taken into account.