The drug "Ladasten" is defined by the instruction as a derivative of adamantane, which has a positive effect on the indicators of mental and physical performance of a person. The basis of the action of this tool is an effective combination of anxiolytic, activating, immunostimulating effect, as well as the so-called elements of actoprotective activity. By the way, an increase in the patient's endurance to various kinds of physical activity directly depends on the latter.
It should be especially noted that during the use of the drug "Ladasten" (the instruction confirms this), there are practically no hyperstimulation phenomena, and such undesirable consequences as, for example, depletion of functional capabilities, are not noted. Moreover, this kind of condition is often recorded in patients taking traditional psychostimulant drugs. In addition, tablets "Ladasten" do not have muscle relaxant and hypnotic properties, as well as addictive potential.
The mechanism of action of the drug
The activity of the drug is due to an increase in the release of dopamine from the presynaptic terminals of the neurotransmitter, blockade of its reuptake process and stimulation of biosynthesis. In addition, it should be said about the modulating effect of the Ladasten preparation (the instruction pays special attention to this) on the GABA-benzodiazepine-chlorionoform complex, which eliminates the decrease in benzodiazepine reception observed in stressful situations. Also, this medicine significantly stimulates GABA-ergic mediation, significantly reducing the expression of the gene responsible for the synthesis of the GABA transporter, which performs reuptake of the mediator.
Description of the therapeutic effect and pharmacokinetics of the drug
After ingestion of the drug, the time to reach its highest concentration in the patient’s blood is on average from two to four hours, with a maximum value of 363 ng / ml. As for the half-life of the drug, then, as a rule, it varies within eleven to twelve hours. Talking about the peculiarities of the therapeutic effect of Ladasten tablets, it should be noted that in patients with a variety of anxiety-asthenic and asthenic disorders, a positive effect begins to appear from the first days of their use in the form of a clear reduction of somatovegetative manifestations, indicators of emotional stress and asthenic symptoms. In addition, this drug helps to quickly increase stamina and restore activity.
The main analogues of the drug
If we consider medications - analogues of Ladasten, then the most similar in terms of the mechanism of action today are such solutions intended for oral administration, such as Velkornin, Adaptokon, Giporolam and Adaptovit, tablets " Life 600 "," Saparal "," Bemaktor "," Safinor "and" Rantarin ". In addition, the capsules “Milife”, “Metaprot” and “Fitovit”, ointments for external use “Apilak Grindeks” and “Apilak” should be included in the same group.
Dosage form and composition of the drug
The drug "Ladasten" is issued, the instructions for which are necessarily included in the kit, in the form of round flat-cylindrical tablets of white or white-cream color, with a chamfer on one side. As an active ingredient, each tablet contains a substance such as adamantyl bromophenylamine. The auxiliary ingredients are magnesium stearate, potato starch and microcrystalline cellulose.
Field of use of the drug
Experts advise people to take this psychostimulant, people suffering from various asthenic conditions provoked by mental stress, infectious and somatic diseases, lack of sleep or overwork. In case of severe intolerance to the usual loads, it is also worth starting to use the Ladasten tablets. Indications for use include absent-mindedness, general weakness, noted even after rest, significantly aggravated by the evening and persisted in the morning. In addition, this drug is often prescribed for hyperesthesia (intolerance to noise and bright light), memory impairment, increased irritability and irritability. Patients suffering from hypersomnia, insomnia or any other sleep disturbances should also start taking the drug “Ladasten”. Indications apply to a disease such as neurasthenia.
Features of use and dosage of the drug
Specialists usually recommend taking these pills twice a day, regardless of the time of eating. In this case, a single dosage of the drug can be from fifty to one hundred milligrams. Take the medication continuously for fourteen to thirty days. Only the attending physician can prescribe a more accurate treatment regimen based on the tests performed and the tests received. It should be emphasized that it is not recommended to use this psychostimulant in the afternoon.
The main contraindications and a list of possible adverse reactions
It is strictly forbidden to take this medication in patients who have not reached the age of eighteen years, as well as in persons suffering from individual intolerance to adamantyl bromophenylamine. During the bearing of the child, it is also worth refusing to take Ladasten tablets. Reviews of doctors indicate that this can be dangerous for the future baby. It is undesirable to use the medication during breastfeeding. In addition, you should not take this medicine for people with an allergic reaction to potato starch or any other auxiliary component present in the composition.
As for the side effects, studies have shown that these tablets are classified as low toxic and, as a rule, are well tolerated by patients. In exceptional cases, sleep disturbance may occur and excessive activation may be noted. The development of such conditions does not require drug withdrawal, but can only provoke a decrease in its initial dosage. In the case of increased sensitivity of the patient's body to one or another component of the drug, the development of a variety of allergic reactions, such as swelling, redness of the skin and others, is possible.