"Efferalgan" (suppositories) is a drug that has an analgesic as well as antipyretic effect. The active ingredient in this drug is paracetamol, which refers to non-steroidal drugs. The medicine "Efferalgan 150" exerts its effect due to the fact that non-selective inhibition of the activity of the cyclooxygenase enzyme occurs, therefore, the synthesis of prostaglandins from arachidonic acid is reduced. Since the number of prostaglandins decreases, a decrease in pain impulses occurs in the central nervous system. And the antipyretic effect that Efferalgan-suppositories have is achieved due to the fact that paracetamol affects the thermoregulation center in the hypothalamus.
This drug is available both in the form of tablets and syrups, and in the form of candles. It is quickly absorbed by the body and exerts its effect 20 minutes after it enters the body. The maximum concentration of paracetamol in the blood is reached within 30-55 minutes after the administration of Efferalgan-suppository. This drug is metabolized in the liver, while pharmacologically inactive metabolites are formed. Metabolites are excreted by the kidneys. The average elimination half-life of the drug "Efferalgan" (suppositories 150 mg) from the body occurs after 2 hours, and after a day up to 90% of all received paracetamol is excreted.
Recommendations for the use of the drug "Efferalgan"
Candles are intended for the treatment of children from 3-5 months of age, whose weight is from 6 kilograms in such cases:
- if the child has a high temperature, which is caused by acute respiratory infections, flu or any other infectious and inflammatory diseases;
- as an anesthetic, if there is a pain syndrome of moderate or weak intensity, it can occur with pain during injuries, muscle pain, burns, headache, as well as toothache, neuralgia.
The drug "Efferalgan" (suppositories) - method of use and recommended doses
Suppositories are administered rectally. To do this, you need to get the candle out of the package and carefully insert the child into the anus, before this you should either have a cleansing enema or wait for the spontaneous bowel movement.
A single dose of this drug depends on the weight of the child and should be 10-15 mg / kg, "Efferalgan" candles are administered 3 to 4 times a day. During the day, you can not take more than 60 mg / kg of this drug.
For children aged 3-5 months, 1 suppository (80 mg) should be used, from 6 months to 3 years - 1 candle of 150 mg each, from 5 to 10 years - 1 candle of 300 mg of the drug. The interval between administrations should be from 4 to 6 hours.
Usually, treatment lasts up to 3 days if the drug is used to lower the temperature, and up to 5 days if it is used as a painkiller. If there is a need to use this drug for a longer period, then you need to carefully monitor the condition of the liver and monitor the condition of peripheral blood.
Also, this tool can be used in the form of syrup or soluble tablets. The doctor prescribes the duration of treatment, however, it is necessary to ensure that the daily dose of paracetamol does not exceed the age norm (regardless of the form in which it is taken).
Possible side effects of the drug "Efferalgan"
Usually, problems after taking this drug do not occur. In isolated cases, the appearance of nausea and vomiting, as well as arterial hypotension, skin allergic reactions, dizziness and increased fatigue.
Contraindications
You can not take this remedy for people with severe liver and kidney diseases, as well as those who can not tolerate fructose and chronic alcoholics. If the child is less than 2 years old or weighs less than 13 kilograms, then effervescent tablets are also not recommended. The drug "Efferalgan" (suppositories) is not used in individuals who have recently suffered inflammation (or bleeding) of the rectum. In this case, it is better to choose a different form of this medicine.