In the autumn-winter period, you can not do without colds, which are often accompanied by cough, obstruction of the bronchi. "Berodual" with saline for inhalation for children during this period becomes simply irreplaceable. Relieves spasm in the lungs, has bronchodilating properties.
Release form and composition of the drug
"Berodual" with saline for inhalation for children is a combined bronchodilator drug. The main active ingredients are: anhydrous ipratropium bromide in an amount of 250 μg and phenoterol hydrobromide in a concentration of 500 μg.
The medicine is made in the form of a solution for inhalation of a transparent color. It is odorless. Packaged in dark brown bottles with a dropper stopper.
Pharmacological effects
"Berodual" with saline for inhalation for children has a pronounced bronchodilator effect. It includes active ingredients: ipratropium bromide acting as m-anticholinergic and phenoterol hydrobromide manifesting itself as beta2-adrenergic agonist.
Fenoterol reduces the tension of the muscles of the bronchi. Prevents repeated cramping, which provokes histamine, methacholine, fresh air and various types of allergens. Taking the drug releases the inflammatory process from the cells of the mediators, and in high doses, the drug is able to enhance mucociliary transport. The component also actively stimulates the respiratory process.
Fenoterol affects the work of the heart. It increases the frequency and strength of contractions, where activation of the β2-adrenergic receptors of the cardiac system occurs, and when the dose is significantly exceeded, there is pressure on the stimulation of β1-adrenergic receptors.
Anhydrous ipratropium bromide acts as a blocker of m-cholinergic receptors. It removes bronchospasm, which is closely related to the activity of the vagus nerve. Reduces the secretion of glands of various genesis, including bronchial.
The introduction of the component by inhalation forms bronchodilation. Does not cause negative effects on mucus of the respiratory tract, mucociliary clearance or gas exchange.
The interaction of active substances helps to create a bronchodilator effect, which is obtained by exposure to various mechanisms. The effect of treatment of bronchopulmonary disease is enhanced. An insignificant dose of a beta-agonist is sufficient to treat the disease, which allows you to get rid of a number of side effects.
Indications
"Berodual" with saline for inhalation for children is used for the prevention and treatment of bronchopulmonary diseases with reversible bronchospasm. These can be chronic and obstructive pulmonary diseases, such as chronic bronchitis, bronchial asthma and emphysema. They recommend using Berodual for coughing.
Often the medicine is used to prepare the respiratory system for the introduction of mucolytic agents, various kinds of corticosteroids and antibiotics administered by the aerosol method.
Contraindication
Reception of the Berodual medicinal solution (the dosage should be in accordance with the instructions) should be prescribed by a doctor, since the drug has contraindications.
These are diseases of the cardiovascular system, such as cardiomyopathy, tachyarrhythmia. It is not recommended to use the medicine with special sensitivity to the active ingredients of the drug and its secondary components.
With caution, prescribe a solution for angle-closure glaucoma, persons with coronary insufficiency and arterial hypertension. People with diabetes mellitus and myocardial infarction should consult a doctor before using the drug. Carefully do inhalation procedures with "Berodual" should be for severe diseases of the cardiovascular system, thyroid gland, in violation of the prostate gland, inflammation of the bladder, as well as during pregnancy and lactation. The question is children's age up to six years.
Application rates
The drug “Berodual” is available only as a solution for inhalation.
The dosage for adults and children over twelve years of age with mild to moderate bronchial asthma attacks is 20 drops, or one milliliter. In a severe form of the disease, higher doses are prescribed - up to 50 drops, or 2.5 ml each. In a particularly severe form, when the patient is in a hospital, the maximum permissible dose of 80 drops, or 4 ml, is recommended.
Children from six to twelve years old with bronchial asthma are prescribed 10 to 20 drops (0.5-1 ml) for quick relief of seizures in mild to moderate form. In a severe form of the disease, up to 40 drops (2 ml) are prescribed. A particularly severe form of the disease, when the patient is under round-the-clock medical supervision, requires a dose of up to 60 drops of a solution or 3 ml each.
With a course of treatment, the drug is prescribed to adults and adolescents from twelve years old, 20-40 drops or 1-2 ml four times a day. The maximum recommended amount is 8 ml. At the age of six to twelve years, children are prescribed up to 0.5-1 ml, this is 10-20 drops four times a day. The maximum allowable dose should be no higher than four milliliters.
With a moderate form of bronchospasm or for additional ventilation of the lungs, the drug is indicated for ten drops, or 0.5 ml, for adults and children from the age group of twelve years, as well as children from six to twelve years old.
Information on the use of the drug for children up to six years of age and weighing less than 22 kg is very limited, therefore it should be used with caution. So, with medical supervision it is advised to take 25 μg ipratropium bromide and 50 μg phenoterol hydrobromide per kilogram of body weight of the child. Norm - 0.5 ml (10 drops). Take the solution in the form of inhalation at least three times a day. The maximum dose should not exceed - 1.5 ml.
How to do inhalation with Berodual
In the case of Berodual, it is important not only to comply with the above standards, but also to use the solution correctly. So, the necessary dose should be diluted with saline to 3-4 ml. The solution is administered orally using a nebulizer. It should be remembered that the reviews of pharmacists emphasize that the solution for inhalation is not under any circumstances diluted with distilled water. Also, the solution must be prepared immediately before the procedure. Residues of the drug are not subject to storage.
The dose of the drug should be determined in accordance with:
- with age;
- type of disease;
- inhalation method;
- view of the nebulizer.
The duration of the event is determined by the amount of fluid remaining in the receiver.
Berodual fits various nebulizer models. In cases where the preparation contains wall oxygen, the solution is used in a speed mode of 6-8 l / min. The procedure, if necessary, is repeated, but not earlier than four hours later.
Side effects
"Berodual" (solution for inhalation) practically does not cause side effects, especially if it is used according to the instructions.
Patients noted that in some cases, after administration of the drug, muscle tremors, slight nervousness, dizziness, dry mouth and a change in taste preferences may be observed. In rare cases, headache, impaired heart function in the form of tachycardia and heart palpitations are noted.
A violation of the respiratory system (cough, irritation of the bronchial ducts) was also noted. Sometimes there is a paradoxical bronchospasm, nausea, vomiting, failure of the gastrointestinal tract. There was a decrease in blood pressure and an increase in the systolic appearance of arrhythmia.
If the solution gets into the eyes, accommodation disturbance, mydriasis, increased intraocular pressure, skin rash, urticaria and edema may occur.
Side effects were manifested in the form of excessive sweating, weakness, hypokalemia, disruption of the genitourinary system, myralgia, muscle cramps.
special instructions
The use of Berodual for inhalation obliges patients to monitor their health. If shortness of breath occurs, you should immediately consult a doctor. In some cases, with a chronic obstructive form of the disease, the periodic use of inhalations may be more fruitful than the course application.
Persons with severe bronchial asthma should remember to conduct and increase the intensity of therapeutic procedures to monitor the inflammatory processes of the bronchopulmonary system and to control the course of the disease.
The constant use of drugs containing beta2-adrenergic agonists, for example, the drug “Berodual”, to suppress bronchial obstruction in some cases provokes a worsening of the disease, therefore it is dangerous to increase the recommended dose. To prevent this situation, the patient's treatment regimen for positive inhalation exposure is being revised.
Joint use of "Berodual" with sympathomimetic bronchodilators is carried out only under strict medical supervision.
Each person before using the solution for inhalation should carefully read the instructions and consult a doctor. When using the drug, avoid contact with eyes. This can trigger the development of glaucoma.
The solution should be inhaled through a special mouthpiece of a nebulizer or a special mask for inhalation.
Interaction with other medicines
"Berodual" (drops) in combination with various beta-adrenergic agonists increase the bronchodilating properties of the drug. A similar effect is observed with complex treatment with anticholinergics and xanthine derivatives.
A decrease in the bronchodilating characteristics of Berodual is possible when combined with beta-blockers. The combination of the drug with xanthine derivatives enhances hypokalemia. This feature should be taken into account by persons with a severe stage of disease of the bronchopulmonary system.
The appearance of hypokalemia, in turn, provokes the appearance of arrhythmia in patients using digoxin in the treatment process, and hypoxia increases the negative effect on the heart rhythm. In this situation, it is advised to constantly monitor the potassium in the blood.
The drug is carefully prescribed to persons taking MAO inhibitors and antidepressants of the tricyclic group. Similar drugs increase the effect of beta-adrenergic drugs. The inhalation process of halogenated hydrocarbon anesthetics enhances the effect of drugs containing beta-adrenergens on the work of the heart. The result of therapeutic treatment can be enhanced by using cromoglycemic acid and glucocorticosteroids.
Drops for inhalation "Berodual": price
You can buy a bronchodilator drug at any pharmacy. Here, the cost of Berodual funds fluctuates insignificantly. Its price is 250-300 rubles.
Analogs of solution for inhalation
More than once proved its effectiveness in the fight against coughing attacks "Berodual." Analogs are practically absent. The exception is the drug "Berodual N".
Some drugs are similar in pharmacological group with drops of "Berodual." Analogs in this area are beta-adrenergic agonists and are used in combination in therapeutic treatment. Such funds include: Biasten, Intal Plus, Ditek, Kashnol, Foradil Combi, Seredit. They will not replace the Berodual solution, but if necessary they can become a good alternative to the drug.